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The map label for this gene is spaK [H]

Identifier: 85060067

GI number: 85060067

Start: 3593869

End: 3594270

Strand: Reverse

Name: spaK [H]

Synonym: SG2089

Alternate gene names: 85060067

Gene position: 3594270-3593869 (Counterclockwise)

Preceding gene: 85060068

Following gene: 85060066

Centisome position: 86.17

GC content: 50.25

Gene sequence:

>402_bases
ATGTACGTTGATATTGCGGCATTGGTGCGTGAGGCGCTGCTGGACAGCGGCTGTGATCCCAGTTTACTGGGGAGTTTCGA
CAGCCATTCCACGATTGCGCTAGACTTTAATGACATGCCAAGTATTTATATCAGCAGCAGCGATGACGATATCTGGCTTT
GGTCGCGCATCGCGGATTACCAGGAAACCCTCATTGAACAATGCTCGTACAAATTGTTAAAAGATCTGCTCGAAGGTGCG
GAGTATATTCGCGGCGGGCATTTTTCGCTGGCTGAAAATGAGGGTTATCTGGAGCTTAAAGCGCTACTGCAACCCTGGTG
CCTGGAGAACAAGCAAAATTTCGCCAGCGCGCTTAGCGGTTTTTTCGAGCGTTTGGAACGCTTCACCAAGGTGTTGCGCT
GA

Upstream 100 bases:

>100_bases
AACATCGTTTTCGCGATCTTGAAGTGCTGTCATTCGGTGAATTAACGGAAAGCGTTACCGTAAATGTCATCAAAACAATT
TAAACCAAGAGGAAAACGAC

Downstream 100 bases:

>100_bases
ATGGAACGGCCGCTGCGAATGCTGCGACGGCAGGCGCTTCCCCTGCGTTTGTCAGGGCCTATTATTGAGGCGGCACTGCC
GGAGGTGGCGGTGGGCGAGA

Product: type III secretion apparatus InvB

Products: NA

Alternate protein names: Invasion protein invB [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MYVDIAALVREALLDSGCDPSLLGSFDSHSTIALDFNDMPSIYISSSDDDIWLWSRIADYQETLIEQCSYKLLKDLLEGA
EYIRGGHFSLAENEGYLELKALLQPWCLENKQNFASALSGFFERLERFTKVLR

Sequences:

>Translated_133_residues
MYVDIAALVREALLDSGCDPSLLGSFDSHSTIALDFNDMPSIYISSSDDDIWLWSRIADYQETLIEQCSYKLLKDLLEGA
EYIRGGHFSLAENEGYLELKALLQPWCLENKQNFASALSGFFERLERFTKVLR
>Mature_133_residues
MYVDIAALVREALLDSGCDPSLLGSFDSHSTIALDFNDMPSIYISSSDDDIWLWSRIADYQETLIEQCSYKLLKDLLEGA
EYIRGGHFSLAENEGYLELKALLQPWCLENKQNFASALSGFFERLERFTKVLR

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spaK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003065 [H]

Pfam domain/function: PF03519 Invas_SpaK [H]

EC number: NA

Molecular weight: Translated: 15168; Mature: 15168

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVDIAALVREALLDSGCDPSLLGSFDSHSTIALDFNDMPSIYISSSDDDIWLWSRIADY
CEEHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHH
QETLIEQCSYKLLKDLLEGAEYIRGGHFSLAENEGYLELKALLQPWCLENKQNFASALSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
FFERLERFTKVLR
HHHHHHHHHHHHC
>Mature Secondary Structure
MYVDIAALVREALLDSGCDPSLLGSFDSHSTIALDFNDMPSIYISSSDDDIWLWSRIADY
CEEHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHH
QETLIEQCSYKLLKDLLEGAEYIRGGHFSLAENEGYLELKALLQPWCLENKQNFASALSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
FFERLERFTKVLR
HHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]