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The map label for this gene is sicA [H]

Identifier: 85060058

GI number: 85060058

Start: 3586905

End: 3587414

Strand: Reverse

Name: sicA [H]

Synonym: SG2080

Alternate gene names: 85060058

Gene position: 3587414-3586905 (Counterclockwise)

Preceding gene: 85060059

Following gene: 85060057

Centisome position: 86.01

GC content: 47.84

Gene sequence:

>510_bases
ATGACTGCTGATAATAATATTCAGAAAAAAAATATCGCTGAAACATTATGGAAGGTGGTAAATAGCGGTGCTGGCGAAGC
GGCTATGCGCGAATTGCCTGAGGGGGGGCTGACGGAGCTGGCAGGCGCTGACGATAATGACGATTTTCAACAACAGCTGG
AAAATGCGGCGGCCTTTTTCAGGTTTCTGTGCATTTACGACTGTCATAACCCGGATTATTATATCGGCCTCGGCGCCGTC
TATCAGTTGCAAAAGCAGTATCAAAAGGCGGCGGATATGTATGCGGTGGCGTTTTCAATGGCCAAGCATGATTACCGGTC
CGTCTTTTATAGCGGCCAATGTCAGGTGCTTATGCATAAAAAGTGCAAAGCGAAGCGCTATTTTCAATTGGTGATTGATC
ATTGCCAGCAACATGAATTGGCACGCTGGGCGTGCCAGAGCCTCAATGAGTTGAATCACTCGCCTCAAGAGCAGGAAATG
CATAATACCAGCTTGGATGATTGCCCCTGA

Upstream 100 bases:

>100_bases
GAATAGATTTTCTTTTGCATAATAATTAAGTGCGTCATTTAGCCCCTATTTTACTCTGATAATTTATCTTACTCGATATG
GCTATTTTCAGGAGATAAAC

Downstream 100 bases:

>100_bases
TATTCGGTGTTATCTTCGACCCGGTGCGATGAGTGTCGCACCTTACGCCAAGGTGGAAGGAGAGCCTGTCTTAAGGTAGG
TTATCGTCGGTGCCGGACGC

Product: putative type III secretion chaperone

Products: NA

Alternate protein names: Salmonella invasin chaperone [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MTADNNIQKKNIAETLWKVVNSGAGEAAMRELPEGGLTELAGADDNDDFQQQLENAAAFFRFLCIYDCHNPDYYIGLGAV
YQLQKQYQKAADMYAVAFSMAKHDYRSVFYSGQCQVLMHKKCKAKRYFQLVIDHCQQHELARWACQSLNELNHSPQEQEM
HNTSLDDCP

Sequences:

>Translated_169_residues
MTADNNIQKKNIAETLWKVVNSGAGEAAMRELPEGGLTELAGADDNDDFQQQLENAAAFFRFLCIYDCHNPDYYIGLGAV
YQLQKQYQKAADMYAVAFSMAKHDYRSVFYSGQCQVLMHKKCKAKRYFQLVIDHCQQHELARWACQSLNELNHSPQEQEM
HNTSLDDCP
>Mature_168_residues
TADNNIQKKNIAETLWKVVNSGAGEAAMRELPEGGLTELAGADDNDDFQQQLENAAAFFRFLCIYDCHNPDYYIGLGAVY
QLQKQYQKAADMYAVAFSMAKHDYRSVFYSGQCQVLMHKKCKAKRYFQLVIDHCQQHELARWACQSLNELNHSPQEQEMH
NTSLDDCP

Specific function: Type III secretion-associated chaperone required for sipB and sipC stabilization. Prevents premature association of sipB with sipC, which may lead to their targeting for degradation. Along with invF, required for transcription activation of sigDE (sopB pi

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lcrH/sycD chaperone family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005415
- InterPro:   IPR016379
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 19338; Mature: 19207

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADNNIQKKNIAETLWKVVNSGAGEAAMRELPEGGLTELAGADDNDDFQQQLENAAAFF
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHH
RFLCIYDCHNPDYYIGLGAVYQLQKQYQKAADMYAVAFSMAKHDYRSVFYSGQCQVLMHK
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KCKAKRYFQLVIDHCQQHELARWACQSLNELNHSPQEQEMHNTSLDDCP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TADNNIQKKNIAETLWKVVNSGAGEAAMRELPEGGLTELAGADDNDDFQQQLENAAAFF
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHH
RFLCIYDCHNPDYYIGLGAVYQLQKQYQKAADMYAVAFSMAKHDYRSVFYSGQCQVLMHK
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KCKAKRYFQLVIDHCQQHELARWACQSLNELNHSPQEQEMHNTSLDDCP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA