Click here to switch to the map view.

The map label for this gene is prgH [H]

Identifier: 85060057

GI number: 85060057

Start: 3585283

End: 3586470

Strand: Reverse

Name: prgH [H]

Synonym: SG2079

Alternate gene names: 85060057

Gene position: 3586470-3585283 (Counterclockwise)

Preceding gene: 85060058

Following gene: 85060056

Centisome position: 85.98

GC content: 59.09

Gene sequence:

>1188_bases
ATGATGAATAAAGAAAATGACCATGTAACGCTGTACCAGGATGGTCTCGTACTCCGATTGCTCAACGGTTTGCTGAAAGG
CTGCGAATATCGCCTCAATGCCCCCGTAACCTTATTTGTCGCAAGCGATGCGGCGCAGGCCGAACGGCGGCATGAGCCGC
CGTTCCTACCGCCGGAGACGATTTTCATTCCCCATCTGCAGGGCGGCGTGAATTTTGAAATAGTTATTGATTTTGTGGCG
CCGCACAAAAGCGCGCTGCGCGTTTTAGTCGATGGCGGCATCAGTGAAACCCCCCTGGTCACCAATCGGGTGTTGACCGC
CGGTCCGCAGGCGTTGGTGGTGAGACCGGCAGCGGCGGCGTGGGATGATACGATTTTGAACTTTCAGGAGATGCCGGCGC
CCGCCATGACGACGCAGCGACGACGCAGGGGCTCCATGGTCCTGCTGTCGCTGATGGTACTGGTTGGCGCGGGTTACCTG
CTGCAAAACTACGCGATCCCCGGGCATGAGGATGCCGCCGCCTTGGGCAAACAGCTCACCGGTGCACAAGGTAAGTTTCA
TCTTTTGCCCGGCAAAGACGGGAGCCTGTACATGCTGGCCAGCAGCGAGCGTGATGCTGCCTTGGGCCGTCAGTCGCTGG
TGCGTCATCCCACCGCCGCGGTGAAGGTGGTGAGCTGTGATGACGAGCGCAGGCGGGTGCACGAATGGCTCGGACGGTAC
TATCCCTGGCTAGGGCTTCATCGCATCCACATCGACGATCCGTCCGCGCCCCAGCTGATTCTCAGCCGACAGCGAGCCGT
CCTCTCTCCAGCGGAGCGGGAGCGGTTGAGCGCGGCGCTGCTGGACATACTGCCCTATGCGCGGCAAATCTCGTTCGGCC
ACTTGGATGACGACGCCGTGGCAAGCGATGCCGAAAATGGTTTACGGCAATTGGCGATCGGCTATGCGCGCGTCGATCAC
CCCGACAGCGTCACTTTTGTGATAAACGGTGCCTTGGAGGATGGTGAGCGCCAGCGGATCCGCCGCTACCTGGAGGCTTT
CAAGCAGCGGTGGAGCAGCAACTATGTGCAGTTTACCGTCGAACTCAGGGATGACCCTATAGCGGGAAAATCTTTTTCCT
ATGGTCAGCAGAACTTTGTCAAACCCAACGCCGGGCACTGGTATTTCACCCCGTCGTCATCTCACTGA

Upstream 100 bases:

>100_bases
CAATAATAATTTATCATATTTTCATCATGAAGTTGAGTCGATGAACAAGGTATGCTTATATTAATTCCCCCGCGGGCTAC
GGTGTTGATAGATATTATGG

Downstream 100 bases:

>100_bases
TAAGGAGATAAAACGTGAGCGGTATCGGTAACCTAAGCCCGATTGGCCTAAGCAGATACGCCGGCAACGCCAGTCAATCC
GTCATTCCTATTGAGTCGAT

Product: type III secretion apparatus

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MMNKENDHVTLYQDGLVLRLLNGLLKGCEYRLNAPVTLFVASDAAQAERRHEPPFLPPETIFIPHLQGGVNFEIVIDFVA
PHKSALRVLVDGGISETPLVTNRVLTAGPQALVVRPAAAAWDDTILNFQEMPAPAMTTQRRRRGSMVLLSLMVLVGAGYL
LQNYAIPGHEDAAALGKQLTGAQGKFHLLPGKDGSLYMLASSERDAALGRQSLVRHPTAAVKVVSCDDERRRVHEWLGRY
YPWLGLHRIHIDDPSAPQLILSRQRAVLSPAERERLSAALLDILPYARQISFGHLDDDAVASDAENGLRQLAIGYARVDH
PDSVTFVINGALEDGERQRIRRYLEAFKQRWSSNYVQFTVELRDDPIAGKSFSYGQQNFVKPNAGHWYFTPSSSH

Sequences:

>Translated_395_residues
MMNKENDHVTLYQDGLVLRLLNGLLKGCEYRLNAPVTLFVASDAAQAERRHEPPFLPPETIFIPHLQGGVNFEIVIDFVA
PHKSALRVLVDGGISETPLVTNRVLTAGPQALVVRPAAAAWDDTILNFQEMPAPAMTTQRRRRGSMVLLSLMVLVGAGYL
LQNYAIPGHEDAAALGKQLTGAQGKFHLLPGKDGSLYMLASSERDAALGRQSLVRHPTAAVKVVSCDDERRRVHEWLGRY
YPWLGLHRIHIDDPSAPQLILSRQRAVLSPAERERLSAALLDILPYARQISFGHLDDDAVASDAENGLRQLAIGYARVDH
PDSVTFVINGALEDGERQRIRRYLEAFKQRWSSNYVQFTVELRDDPIAGKSFSYGQQNFVKPNAGHWYFTPSSSH
>Mature_395_residues
MMNKENDHVTLYQDGLVLRLLNGLLKGCEYRLNAPVTLFVASDAAQAERRHEPPFLPPETIFIPHLQGGVNFEIVIDFVA
PHKSALRVLVDGGISETPLVTNRVLTAGPQALVVRPAAAAWDDTILNFQEMPAPAMTTQRRRRGSMVLLSLMVLVGAGYL
LQNYAIPGHEDAAALGKQLTGAQGKFHLLPGKDGSLYMLASSERDAALGRQSLVRHPTAAVKVVSCDDERRRVHEWLGRY
YPWLGLHRIHIDDPSAPQLILSRQRAVLSPAERERLSAALLDILPYARQISFGHLDDDAVASDAENGLRQLAIGYARVDH
PDSVTFVINGALEDGERQRIRRYLEAFKQRWSSNYVQFTVELRDDPIAGKSFSYGQQNFVKPNAGHWYFTPSSSH

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 43941; Mature: 43941

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNKENDHVTLYQDGLVLRLLNGLLKGCEYRLNAPVTLFVASDAAQAERRHEPPFLPPET
CCCCCCCEEEEEECCHHHHHHHHHHHCCCEECCCCEEEEEECCHHHHHHCCCCCCCCCCC
IFIPHLQGGVNFEIVIDFVAPHKSALRVLVDGGISETPLVTNRVLTAGPQALVVRPAAAA
EEEECCCCCCEEEEEEEEECCCHHHEEEEECCCCCCCCCHHCCEECCCCCEEEEECCHHC
WDDTILNFQEMPAPAMTTQRRRRGSMVLLSLMVLVGAGYLLQNYAIPGHEDAAALGKQLT
CCHHHHCHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHC
GAQGKFHLLPGKDGSLYMLASSERDAALGRQSLVRHPTAAVKVVSCDDERRRVHEWLGRY
CCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
YPWLGLHRIHIDDPSAPQLILSRQRAVLSPAERERLSAALLDILPYARQISFGHLDDDAV
CCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ASDAENGLRQLAIGYARVDHPDSVTFVINGALEDGERQRIRRYLEAFKQRWSSNYVQFTV
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
ELRDDPIAGKSFSYGQQNFVKPNAGHWYFTPSSSH
EECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MMNKENDHVTLYQDGLVLRLLNGLLKGCEYRLNAPVTLFVASDAAQAERRHEPPFLPPET
CCCCCCCEEEEEECCHHHHHHHHHHHCCCEECCCCEEEEEECCHHHHHHCCCCCCCCCCC
IFIPHLQGGVNFEIVIDFVAPHKSALRVLVDGGISETPLVTNRVLTAGPQALVVRPAAAA
EEEECCCCCCEEEEEEEEECCCHHHEEEEECCCCCCCCCHHCCEECCCCCEEEEECCHHC
WDDTILNFQEMPAPAMTTQRRRRGSMVLLSLMVLVGAGYLLQNYAIPGHEDAAALGKQLT
CCHHHHCHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHC
GAQGKFHLLPGKDGSLYMLASSERDAALGRQSLVRHPTAAVKVVSCDDERRRVHEWLGRY
CCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
YPWLGLHRIHIDDPSAPQLILSRQRAVLSPAERERLSAALLDILPYARQISFGHLDDDAV
CCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ASDAENGLRQLAIGYARVDHPDSVTFVINGALEDGERQRIRRYLEAFKQRWSSNYVQFTV
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
ELRDDPIAGKSFSYGQQNFVKPNAGHWYFTPSSSH
EECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]