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The map label for this gene is nuoA

Identifier: 85059579

GI number: 85059579

Start: 2748180

End: 2748617

Strand: Reverse

Name: nuoA

Synonym: SG1601

Alternate gene names: 85059579

Gene position: 2748617-2748180 (Counterclockwise)

Preceding gene: 85059582

Following gene: 85059578

Centisome position: 65.9

GC content: 56.16

Gene sequence:

>438_bases
ATGTCGATAACTACTGAAATTACCGCTCATTATTGGGCTTTCGCCGTATTCCTCCTGAGTGCGCTGGGTCTGTGCGTCTT
CATGCTTACCGGCGGTTTCCTGCTGGGCGCCCGCGCCCGGGCGCGCTCGAAAAACGTGCCGTTTGAATCTGGGATCGACC
CGGTGGGCACCGCAAGATTGCGCCTTTCAGCTAAATTTTACCTTGTGGCGATGTTTTTCGTCATTTTCGACGTTGAAACC
CTCTATCTTTATGCCTGGGCTACCGCTATTCGCGAAGCGGGCTGGGTGGGCTTCATCGAGGCAACCATTTTCATTCTTAT
CCTGTTGGCGGGTTTGGTTTACCTGGTGCGTATCGGTGCCCTTGACTGGACGCCGGAGCGCTCCCGACGTTTGCGCCGGG
CAGGCCCCATTGGCGAAACCCCCCGTCATCAAGAGTAA

Upstream 100 bases:

>100_bases
ATGGTTTCTTACTTCCTTCCCGTAAATCGATGTGATGCGTAAAACTGCCGAATTCATAGAGCAGCCTGCAAATCGCCACT
TTTGATGAGTAGCAAAGAGA

Downstream 100 bases:

>100_bases
CAGCGAGGCAGCAAAATGGATTACACCCTCACCCGCGCGGAGCCGGACGGAGATAACGAGCGGTATCCCCTGCAAAAACA
GGAAATCGTGGCGGATCCGC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARLRLSAKFYLVAMFFVIFDVET
LYLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGALDWTPERSRRLRRAGPIGETPRHQE

Sequences:

>Translated_145_residues
MSITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARLRLSAKFYLVAMFFVIFDVET
LYLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGALDWTPERSRRLRRAGPIGETPRHQE
>Mature_144_residues
SITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARLRLSAKFYLVAMFFVIFDVETL
YLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGALDWTPERSRRLRRAGPIGETPRHQE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=144, Percent_Identity=72.9166666666667, Blast_Score=218, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_SODGM (Q2NSJ9)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455281.1
- STRING:   Q2NSJ9
- GeneID:   3867896
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1601
- NMPDR:   fig|343509.6.peg.3409
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- PhylomeDB:   Q2NSJ9
- ProtClustDB:   PRK06602
- BioCyc:   SGLO343509:SG1601-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 16245; Mature: 16114

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfa20ac8)-; HASH(0xdd083c4)-; HASH(0xfb55674)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RLSAKFYLVAMFFVIFDVETLYLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPERSRRLRRAGPIGETPRHQE
CCCCHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
SITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RLSAKFYLVAMFFVIFDVETLYLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPERSRRLRRAGPIGETPRHQE
CCCCHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA