BacMap

Definition	Sodalis glossinidius str. 'morsitans', complete genome.
Accession	NC_007712
Length	4,171,146

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The map label for this gene is ydfG [H]

Identifier: 85059448

GI number: 85059448

Start: 2457067

End: 2457816

Strand: Reverse

Name: ydfG [H]

Synonym: SG1470

Alternate gene names: 85059448

Gene position: 2457816-2457067 (Counterclockwise)

Preceding gene: 85059450

Following gene: 85059446

Centisome position: 58.92

GC content: 58.27

Gene sequence:

>750_bases
ATGATTATTTTCGTTACCGGCGCTACTGCCGGCTTTGGCGAAGCCATTACCCGTTTGTTTATAAAGAAGGGACATAAGGT
TATCGGGACCGGTCGCCGTGAGGCCCGTCTCAAAGAGCTCCGGCAGGAGTTGGGCGACGCCTTCCTACCGCTGCAACTTG
ACGTGCGGGACAGAGCGGCTATTGCCGAACAGGGGAGCCTGTTGCCGGCCGAATGGCGTGAGGTCGATGTGCTGGTGAAT
AACGCTGGTCTAGCGCTGGGCATGGAGCCGGCGCAAAACGCCAATCTGGATGACTGGGAAACCATGATCGACACCAACAA
TAAGGGCCTGGTCTATATGACCCGCGCGCTGTTGCCGGGTATGGTCGAGCGCAGACGCGGGCATATTATCAACCTTGGCT
CTACGGCCGGTCGCTGGCCCTATGCCGGGGGCAATGTGTATGGCGCCACCAAGGCCTTTACCCGTCATTTCAGCCTGAAT
TTGCGCACCGATCTGGTTGGCACGCGCGTCAGGGTGACGGATATCGAACCCGGCCTGGTAGGCGGTACGGAGTTCTCGTC
GGTGCGGTTCAAAGGCGATGAAGGCAAGGTGGAAAACACCTATAAAAATGCCGATCCGCTCATGCCGGATGATATCGCCG
GGGCCGTATTTTGGGTGGCAACCCTGCCCGACCATGTCAATATCAATGTCCTGGAAATGATGCCGGTCTGCCAGTCCTTC
GCGGGGCTCAGCGTGTATCGCGAGGGCTGA

Upstream 100 bases:

>100_bases
GGATTTGTCCCTGATAGCCCCCTATCTGCGTCACCCCTAATCGCACAGGATCTATAATGGGGTATTTATGGGTCTGTCAT
CACCAAAAAGGAACCTAACA

Downstream 100 bases:

>100_bases
TATAGCCAATGCGCTTCGCCCCGGGGCCGCGGCCGCCTAGTGAGACCTCCGTGTCGGGCACCCACAGGCAAAGCCCGCCA
GATCCACGCCGCTTTCTGCG

Product: 3-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIIFVTGATAGFGEAITRLFIKKGHKVIGTGRREARLKELRQELGDAFLPLQLDVRDRAAIAEQGSLLPAEWREVDVLVN
NAGLALGMEPAQNANLDDWETMIDTNNKGLVYMTRALLPGMVERRRGHIINLGSTAGRWPYAGGNVYGATKAFTRHFSLN
LRTDLVGTRVRVTDIEPGLVGGTEFSSVRFKGDEGKVENTYKNADPLMPDDIAGAVFWVATLPDHVNINVLEMMPVCQSF
AGLSVYREG

Sequences:

>Translated_249_residues
MIIFVTGATAGFGEAITRLFIKKGHKVIGTGRREARLKELRQELGDAFLPLQLDVRDRAAIAEQGSLLPAEWREVDVLVN
NAGLALGMEPAQNANLDDWETMIDTNNKGLVYMTRALLPGMVERRRGHIINLGSTAGRWPYAGGNVYGATKAFTRHFSLN
LRTDLVGTRVRVTDIEPGLVGGTEFSSVRFKGDEGKVENTYKNADPLMPDDIAGAVFWVATLPDHVNINVLEMMPVCQSF
AGLSVYREG
>Mature_249_residues
MIIFVTGATAGFGEAITRLFIKKGHKVIGTGRREARLKELRQELGDAFLPLQLDVRDRAAIAEQGSLLPAEWREVDVLVN
NAGLALGMEPAQNANLDDWETMIDTNNKGLVYMTRALLPGMVERRRGHIINLGSTAGRWPYAGGNVYGATKAFTRHFSLN
LRTDLVGTRVRVTDIEPGLVGGTEFSSVRFKGDEGKVENTYKNADPLMPDDIAGAVFWVATLPDHVNINVLEMMPVCQSF
AGLSVYREG

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=31.8548387096774, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=30.8510638297872, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=32.1052631578947, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40548397, Length=184, Percent_Identity=33.1521739130435, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI214010158, Length=184, Percent_Identity=33.1521739130435, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI214010156, Length=184, Percent_Identity=33.1521739130435, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI22758144, Length=184, Percent_Identity=33.1521739130435, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=32.1052631578947, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI22507405, Length=183, Percent_Identity=31.1475409836066, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=29.2553191489362, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=28.7878787878788, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI19743808, Length=183, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=25.668449197861, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI10190704, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI19923817, Length=188, Percent_Identity=23.936170212766, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI50726952, Length=185, Percent_Identity=28.6486486486486, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=74.5967741935484, Blast_Score=389, Evalue=1e-110,
Organism=Escherichia coli, GI1787335, Length=184, Percent_Identity=33.1521739130435, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=242, Percent_Identity=26.8595041322314, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=191, Percent_Identity=28.7958115183246, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=241, Percent_Identity=28.6307053941909, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=186, Percent_Identity=25.8064516129032, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=189, Percent_Identity=28.042328042328, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=187, Percent_Identity=31.5508021390374, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=195, Percent_Identity=31.7948717948718, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=243, Percent_Identity=25.1028806584362, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=234, Percent_Identity=26.0683760683761, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=235, Percent_Identity=25.9574468085106, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=184, Percent_Identity=25.5434782608696, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=238, Percent_Identity=25.6302521008403, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=190, Percent_Identity=27.3684210526316, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=36.3265306122449, Blast_Score=152, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6322227, Length=248, Percent_Identity=27.0161290322581, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=184, Percent_Identity=27.7173913043478, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.9772727272727, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=255, Percent_Identity=32.156862745098, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281364494, Length=249, Percent_Identity=31.3253012048193, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21358495, Length=222, Percent_Identity=30.6306306306306, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI23397609, Length=181, Percent_Identity=32.0441988950276, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28571387, Length=258, Percent_Identity=29.8449612403101, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=31.7948717948718, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648693, Length=252, Percent_Identity=28.1746031746032, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355889, Length=252, Percent_Identity=28.1746031746032, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24643142, Length=179, Percent_Identity=31.8435754189944, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24584748, Length=180, Percent_Identity=30, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI161076933, Length=180, Percent_Identity=30, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24641232, Length=259, Percent_Identity=27.4131274131274, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24663911, Length=253, Percent_Identity=28.0632411067194, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007238, Length=188, Percent_Identity=32.9787234042553, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641388, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=28.0632411067194, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=183, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584744, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=180, Percent_Identity=30, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27317; Mature: 27317

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFVTGATAGFGEAITRLFIKKGHKVIGTGRREARLKELRQELGDAFLPLQLDVRDRAA
CEEEEECCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCEEEECCCHHHH
IAEQGSLLPAEWREVDVLVNNAGLALGMEPAQNANLDDWETMIDTNNKGLVYMTRALLPG
HHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCHHHHHHCCCCCCEEEEHHHHHHH
MVERRRGHIINLGSTAGRWPYAGGNVYGATKAFTRHFSLNLRTDLVGTRVRVTDIEPGLV
HHHHHCCCEEEECCCCCCCCCCCCCEEEHHHHHHEEEEEEEEECCCCCEEEEEECCCCCC
GGTEFSSVRFKGDEGKVENTYKNADPLMPDDIAGAVFWVATLPDHVNINVLEMMPVCQSF
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCEEHHHHHHHHHHH
AGLSVYREG
HCCEEEECC
>Mature Secondary Structure
MIIFVTGATAGFGEAITRLFIKKGHKVIGTGRREARLKELRQELGDAFLPLQLDVRDRAA
CEEEEECCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCEEEECCCHHHH
IAEQGSLLPAEWREVDVLVNNAGLALGMEPAQNANLDDWETMIDTNNKGLVYMTRALLPG
HHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCHHHHHHCCCCCCEEEEHHHHHHH
MVERRRGHIINLGSTAGRWPYAGGNVYGATKAFTRHFSLNLRTDLVGTRVRVTDIEPGLV
HHHHHCCCEEEECCCCCCCCCCCCCEEEHHHHHHEEEEEEEEECCCCCEEEEEECCCCCC
GGTEFSSVRFKGDEGKVENTYKNADPLMPDDIAGAVFWVATLPDHVNINVLEMMPVCQSF
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCEEHHHHHHHHHHH
AGLSVYREG
HCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]