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The map label for this gene is dsbB

Identifier: 85059318

GI number: 85059318

Start: 2223353

End: 2223883

Strand: Reverse

Name: dsbB

Synonym: SG1340

Alternate gene names: 85059318

Gene position: 2223883-2223353 (Counterclockwise)

Preceding gene: 85059319

Following gene: 85059314

Centisome position: 53.32

GC content: 56.5

Gene sequence:

>531_bases
ATGATGCGATCGTTAAACCGCTGCTCCAAACATCGCGCAGCCTGGTTACTATTGGCACTCACCACCTTCTCGCTGGAACT
GGTCGCGCTTTATTTTCAGCATGTTATGCTGCTCAAACCCTGCGTTTTGTGTGTATATCAACGTTGTGCTCTGTATGGCG
TCGTTGCCGCCGGGCTGGTGGGCGCCATCGCCCCCGCGACGCCGCTGCGTTTCTCCGGCCTGGCAATATGGTTGTATAGC
GCTTGGGAGGGCCTGCAGCTGGCGATGAAACACACCGATATTCAACTGCATCCCTCCCCGTTCGTCACCTGCGACTTTTT
TGTCAGTTTTCCTGCCTGGCTACCGTTGGATAAGTGGCTTCCGTCGGTCTTCAGCGCCAGCGGTGACTGCGCCGTCCGCC
AATGGCATTTCCTGTCGCTGGAAATGCCGCAATGGATGATCGTCATCTTCGGCGCCTATCTGGCGGTCGCGGTACTCATT
TTGCTTGCGCAATTCTTCCCCCCGCGCAAACGCGACCTTTTTTCACGCTGA

Upstream 100 bases:

>100_bases
GCGGCCTCAGGCATGCGGCTGGCGGAAAAGACGCTGGTTTCTGTTGTTTTTTGATTTAGAATGCTCGTTTCACGCCACTT
AACTGTTCTGGACACTCTTT

Downstream 100 bases:

>100_bases
TGACGGCACGACGGCGTTACTACGCCGTCACACGCAGGCCATCGCTCCCCGGCGAGCGGATTATCTCGCCGCTTTCGATA
ATCGTTTCTGCACGTTGCGC

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLVGAIAPATPLRFSGLAIWLYS
AWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWLPSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLI
LLAQFFPPRKRDLFSR

Sequences:

>Translated_176_residues
MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLVGAIAPATPLRFSGLAIWLYS
AWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWLPSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLI
LLAQFFPPRKRDLFSR
>Mature_176_residues
MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLVGAIAPATPLRFSGLAIWLYS
AWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWLPSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLI
LLAQFFPPRKRDLFSR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=66.4772727272727, Blast_Score=252, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_SODGM (Q2NTB0)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455020.1
- ProteinModelPortal:   Q2NTB0
- SMR:   Q2NTB0
- STRING:   Q2NTB0
- GeneID:   3866411
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1340
- NMPDR:   fig|343509.6.peg.2739
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- PhylomeDB:   Q2NTB0
- ProtClustDB:   PRK01749
- BioCyc:   SGLO343509:SG1340-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19951; Mature: 19951

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf41d744)-; HASH(0xf4169e0)-; HASH(0xefe0098)-; HASH(0xe33f594)-;

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPATPLRFSGLAIWLYSAWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEHHHHHHCCCCCCHHHHH
PSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLILLAQFFPPRKRDLFSR
HHHHCCCCCHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCH
>Mature Secondary Structure
MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPATPLRFSGLAIWLYSAWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEHHHHHHCCCCCCHHHHH
PSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLILLAQFFPPRKRDLFSR
HHHHCCCCCHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA