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The map label for this gene is minC

Identifier: 85059314

GI number: 85059314

Start: 2218489

End: 2219166

Strand: Reverse

Name: minC

Synonym: SG1336

Alternate gene names: 85059314

Gene position: 2219166-2218489 (Counterclockwise)

Preceding gene: 85059318

Following gene: 85059313

Centisome position: 53.2

GC content: 55.75

Gene sequence:

>678_bases
ATGTCGCAAACGCCAATTGAGTTGAAAGGCAGTAATTTTACTTTATCGGTAATTCATGTGCATGATGCTCAGCCAGAGGA
AATCCGTCGGGCGATAGAGGAAAAAGTCGAAAAAGCACCTGGATTTTTAAAAAATGCGCCGGTGGTCATCAACGTCGCCG
GTCTTGGTCGTGACACCTCCTGGGAGGCGCTGTCGCAGGCGGTGCTGGCCACCGGTCTGCACATCGTCGGCGTCAGCGGT
TGCAGCGACAGTAAGCTTAAACAGGCGATCGTGCGCAGCGGGTTGCCTCTGCTGACCGAAGGTAAAGCGCCGAAGCGCAG
CGTCGACGCAACACCCGCCCTGGCGGCGGTCAAAACACGGCTTATCAACACGCCGGTGCGCTCCGGGCAACAAATTTACG
CCCGCAGTAGCAATCTGATCGTCACCAGCAGCGTCAGCGCCGGCGCCGAGCTTATTGCCGATGGCAATATACATATTTAT
GGCATGATGCGGGGTCGCGCGCTGGCCGGTGCGTCGGGGGACGGAGAGTGCCAAATTTTCTGCACCCATCTCTCTCCCGA
ACTCATATCTATTGCTGGCCAGTATTGGCTGAGCGATCAAATTCCGGCCGCGCTTTTAGGCAAAGCCGCGCGTTTATGTC
TGCAAGACGGCACGCTTACCATTCATCCTTTAATTTAG

Upstream 100 bases:

>100_bases
GCCTGTATATAGCGGTAACTATAACATGCATGCAGTACTACGGAATATCGCCTCCCGTGACGAAACGGGAAATACACGTG
CTAAGACTGAGTCAGGATAG

Downstream 100 bases:

>100_bases
CCCTTGACAAGGAATTTATTTATGGCATGCATTATAGTTGTTACTTCGGGTAAAGGGGGGGTTGGCAAGACCACATCGAG
CGCGGCCATCGCTACCGGTT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTSWEALSQAVLATGLHIVGVSG
CSDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTRLINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIY
GMMRGRALAGASGDGECQIFCTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI

Sequences:

>Translated_225_residues
MSQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTSWEALSQAVLATGLHIVGVSG
CSDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTRLINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIY
GMMRGRALAGASGDGECQIFCTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI
>Mature_224_residues
SQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTSWEALSQAVLATGLHIVGVSGC
SDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTRLINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIYG
MMRGRALAGASGDGECQIFCTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=230, Percent_Identity=63.0434782608696, Blast_Score=293, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SODGM (Q2NTB4)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455016.1
- ProteinModelPortal:   Q2NTB4
- STRING:   Q2NTB4
- GeneID:   3866407
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1336
- NMPDR:   fig|343509.6.peg.2734
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   IFCTHLA
- PhylomeDB:   Q2NTB4
- ProtClustDB:   PRK03511
- BioCyc:   SGLO343509:SG1336-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23736; Mature: 23604

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTS
CCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
WEALSQAVLATGLHIVGVSGCSDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTR
HHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
LINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIYGMMRGRALAGASGDGECQIF
HHCCCCCCCCEEEECCCCEEEEECCCCCEEEEECCCEEEEEEEECCEEECCCCCCCEEEE
CTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI
EECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEEECC
>Mature Secondary Structure 
SQTPIELKGSNFTLSVIHVHDAQPEEIRRAIEEKVEKAPGFLKNAPVVINVAGLGRDTS
CCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
WEALSQAVLATGLHIVGVSGCSDSKLKQAIVRSGLPLLTEGKAPKRSVDATPALAAVKTR
HHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
LINTPVRSGQQIYARSSNLIVTSSVSAGAELIADGNIHIYGMMRGRALAGASGDGECQIF
HHCCCCCCCCEEEECCCCEEEEECCCCCEEEEECCCEEEEEEEECCEEECCCCCCCEEEE
CTHLSPELISIAGQYWLSDQIPAALLGKAARLCLQDGTLTIHPLI
EECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA