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The map label for this gene is minD [H]

Identifier: 85059313

GI number: 85059313

Start: 2217655

End: 2218467

Strand: Reverse

Name: minD [H]

Synonym: SG1335

Alternate gene names: 85059313

Gene position: 2218467-2217655 (Counterclockwise)

Preceding gene: 85059314

Following gene: 85059312

Centisome position: 53.19

GC content: 51.17

Gene sequence:

>813_bases
ATGGCATGCATTATAGTTGTTACTTCGGGTAAAGGGGGGGTTGGCAAGACCACATCGAGCGCGGCCATCGCTACCGGTTT
AGCCCGCAAAGGAAAGAAAACCGTAGTGATCGATTTCGATATCGGGCTGCGAAATCTTGATTTGATCATGGGCTGTGAAC
GCCGAGTGGTCTATGACTTCGTCAATGTCATCCAGGGTGATGCCACACTGAATCAGGCGCTGATAAAAGACAAACGGACC
GAAAATTTATATATCCTGCCGGCGTCCCAAACGCGGGATAAAGATGCCCTGACCCGAGAGGGCGTGGAAAAAGTGTTGAA
TGATTTAGGCACGATGGAATTCGATTTTGTCGTCTGCGATTCACCGGCCGGTATTGAAACCGGTGCCCTGATGGCACTGT
ATTTTGCCGATGAAGCCATTATCACTACTAACCCGGAAGTCTCGTCGGTGCGTGACTCAGACCGTATATTGGGTATCCTG
TCGTCGAAATCGCGCCGTGCCGAAAATGGTCTGGAGCCAATCAAAGAGCACCTGATGTTGACCCGCTACAATCCTGGACG
CGTCAGCCGCGGCGACATGCTTAGCATGGAAGATGTCATTGAAATTCTACGCATTCCCTTGGTGGGTGTGATCCCCGAGG
ATCAATCGGTATTGCGGGCCTCCAACCAGGGTGAGCCGGTGATTCTTGATGAGGAATCTGATGCTGGCCAGGCCTATTCA
GATATGGTTGATCGCTTGTTAGGGGAAGAACGTCCCTTCCGCTTCATCGAAGAAGAAAAGAAGGGATTCCTGAAACGCCT
GTTTGGGGGATAA

Upstream 100 bases:

>100_bases
AATTCCGGCCGCGCTTTTAGGCAAAGCCGCGCGTTTATGTCTGCAAGACGGCACGCTTACCATTCATCCTTTAATTTAGC
CCTTGACAAGGAATTTATTT

Downstream 100 bases:

>100_bases
ACCATGGCATTGCTAGACTTTTTTCTCTCCCGTAAAAAATCGACAGCCAATATAGCCAAGGAACGGCTGCAGATCATCGT
GGCCGAACGGCGCAGAGGCG

Product: cell division inhibitor MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MACIIVVTSGKGGVGKTTSSAAIATGLARKGKKTVVIDFDIGLRNLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRT
ENLYILPASQTRDKDALTREGVEKVLNDLGTMEFDFVVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
SSKSRRAENGLEPIKEHLMLTRYNPGRVSRGDMLSMEDVIEILRIPLVGVIPEDQSVLRASNQGEPVILDEESDAGQAYS
DMVDRLLGEERPFRFIEEEKKGFLKRLFGG

Sequences:

>Translated_270_residues
MACIIVVTSGKGGVGKTTSSAAIATGLARKGKKTVVIDFDIGLRNLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRT
ENLYILPASQTRDKDALTREGVEKVLNDLGTMEFDFVVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
SSKSRRAENGLEPIKEHLMLTRYNPGRVSRGDMLSMEDVIEILRIPLVGVIPEDQSVLRASNQGEPVILDEESDAGQAYS
DMVDRLLGEERPFRFIEEEKKGFLKRLFGG
>Mature_269_residues
ACIIVVTSGKGGVGKTTSSAAIATGLARKGKKTVVIDFDIGLRNLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTE
NLYILPASQTRDKDALTREGVEKVLNDLGTMEFDFVVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGILS
SKSRRAENGLEPIKEHLMLTRYNPGRVSRGDMLSMEDVIEILRIPLVGVIPEDQSVLRASNQGEPVILDEESDAGQAYSD
MVDRLLGEERPFRFIEEEKKGFLKRLFGG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=92.2222222222222, Blast_Score=502, Evalue=1e-143,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29657; Mature: 29526

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACIIVVTSGKGGVGKTTSSAAIATGLARKGKKTVVIDFDIGLRNLDLIMGCERRVVYDF
CEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGVEKVLNDLGTMEFDFVVCD
HHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEC
SPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGILSSKSRRAENGLEPIKEHLML
CCCCCCCCCEEEEEECCCEEEECCCCHHHCCCCCCEEEECCCCCHHHHCCHHHHHHHHEE
TRYNPGRVSRGDMLSMEDVIEILRIPLVGVIPEDQSVLRASNQGEPVILDEESDAGQAYS
EECCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEEECCCCCCHHHH
DMVDRLLGEERPFRFIEEEKKGFLKRLFGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ACIIVVTSGKGGVGKTTSSAAIATGLARKGKKTVVIDFDIGLRNLDLIMGCERRVVYDF
EEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGVEKVLNDLGTMEFDFVVCD
HHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEC
SPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGILSSKSRRAENGLEPIKEHLML
CCCCCCCCCEEEEEECCCEEEECCCCHHHCCCCCCEEEECCCCCHHHHCCHHHHHHHHEE
TRYNPGRVSRGDMLSMEDVIEILRIPLVGVIPEDQSVLRASNQGEPVILDEESDAGQAYS
EECCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHCCCCCEEEEECCCCCCHHHH
DMVDRLLGEERPFRFIEEEKKGFLKRLFGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]