Click here to switch to the map view.

The map label for this gene is minE

Identifier: 85059312

GI number: 85059312

Start: 2217382

End: 2217651

Strand: Reverse

Name: minE

Synonym: SG1334

Alternate gene names: 85059312

Gene position: 2217651-2217382 (Counterclockwise)

Preceding gene: 85059313

Following gene: 85059309

Centisome position: 53.17

GC content: 50.37

Gene sequence:

>270_bases
ATGGCATTGCTAGACTTTTTTCTCTCCCGTAAAAAATCGACAGCCAATATAGCCAAGGAACGGCTGCAGATCATCGTGGC
CGAACGGCGCAGAGGCGATAACGAACCGCATTATCTGCCGCAGCTGAAACGTGACCTGCTTGAGGTCATCAGCAAATATG
TGCAAATCGACCCCGAAATGCTCTCGGTGCAGCTGGAAAAAAAGGATGGGGATATCTCGATCCTGGAGCTGAACGTGACC
CTGCCGGAAACGGAAGAGACTACGAAATAA

Upstream 100 bases:

>100_bases
TTCAGATATGGTTGATCGCTTGTTAGGGGAAGAACGTCCCTTCCGCTTCATCGAAGAAGAAAAGAAGGGATTCCTGAAAC
GCCTGTTTGGGGGATAAACC

Downstream 100 bases:

>100_bases
GCGTCTGCGCCTGACACGCCTGCAATCGACCGGCAGGCGGCCAGCGCCGTTATGGACCCGCCGTAGGCTCTGCACGCCTG
GCCAGTGACGTTCCTGAATC

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 88

Protein sequence:

>89_residues
MALLDFFLSRKKSTANIAKERLQIIVAERRRGDNEPHYLPQLKRDLLEVISKYVQIDPEMLSVQLEKKDGDISILELNVT
LPETEETTK

Sequences:

>Translated_89_residues
MALLDFFLSRKKSTANIAKERLQIIVAERRRGDNEPHYLPQLKRDLLEVISKYVQIDPEMLSVQLEKKDGDISILELNVT
LPETEETTK
>Mature_88_residues
ALLDFFLSRKKSTANIAKERLQIIVAERRRGDNEPHYLPQLKRDLLEVISKYVQIDPEMLSVQLEKKDGDISILELNVTL
PETEETTK

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

Organism=Escherichia coli, GI1787422, Length=86, Percent_Identity=87.2093023255814, Blast_Score=156, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_SODGM (Q2NTB6)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455014.1
- ProteinModelPortal:   Q2NTB6
- SMR:   Q2NTB6
- STRING:   Q2NTB6
- GeneID:   3866405
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1334
- NMPDR:   fig|343509.6.peg.2732
- eggNOG:   COG0851
- HOGENOM:   HBG449956
- OMA:   PAYLPDM
- PhylomeDB:   Q2NTB6
- ProtClustDB:   PRK00296
- BioCyc:   SGLO343509:SG1334-MONOMER
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 10324; Mature: 10193

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDFFLSRKKSTANIAKERLQIIVAERRRGDNEPHYLPQLKRDLLEVISKYVQIDPEM
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LSVQLEKKDGDISILELNVTLPETEETTK
EEEEEECCCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
ALLDFFLSRKKSTANIAKERLQIIVAERRRGDNEPHYLPQLKRDLLEVISKYVQIDPEM
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LSVQLEKKDGDISILELNVTLPETEETTK
EEEEEECCCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA