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The map label for this gene is pabB [H]

Identifier: 85059307

GI number: 85059307

Start: 2210722

End: 2212092

Strand: Reverse

Name: pabB [H]

Synonym: SG1329

Alternate gene names: 85059307

Gene position: 2212092-2210722 (Counterclockwise)

Preceding gene: 85059309

Following gene: 85059306

Centisome position: 53.03

GC content: 62.36

Gene sequence:

>1371_bases
TTGACCATGCAGCCACAACTGACAGCATTACCCTATCGGCCCGATGCCGTTCTGGATTTTTTTACCCCTTTCGCCGGCCA
GCCCTGGTCGATACTGTTGCATTCCGGTCATAGTGACCATCCCGATAGCCGTTACGATATCCTGGTGGCCGCGCCAGCGG
TGACGCTTGTCACGCGTGACGGTGTCACTGAAGTCCGCTGGGGGGAAACGTGCGAGCTCCGGGATGACGATCCCTTTGCG
CTGGTGCAACAGCAGTTGGCGGCGGTAGGCATGATGGCGTCGCCGAATGCGGAATTACCGTTTCAGGGAGGGGCGCTCGG
GTATTTTGGCTATGATCTTGCCCGCGGCATCGAAACTTTGCCGGTATTGGCGCAACAGGATCTCCCGCTGCCGGACATGG
CAATTGGGATTTACCGCTGGGCGGTGGTGGCCGACCATCACCGCCGTACGGTGACGCTGGTCAGCCACGACGATCCCACC
CCCATACTTGCCCGGTTAACCGCAGCGCCGCCCGCGCCGCCCGCGCCGTTTCATCTGCTCGGGCCCTGGCACGCCAATAT
GACCAGCGCCGACTATGGCGATAAATTCCGCCAGGTGCAGCAGCACCTGCTGGTGGGTGACTGCTATCAAGTCTGTCTGT
CACAGCGTTTCAGCGCCCCCTGCGATGGCGATGAATGGCCGGCGTTCCGCCTCTTGCTGGCCCACAACCGGGCGCCCTTC
TCGGCGTTTATCCGCCTGGCGGACCAGACGACGGTGCTCAGCTTGTCGCCGGAACGTTTCCTGCGCCTGCGCGGCGGCGA
GATCCAGACCCGCCCCATCAAAGGCACATTACCCCGGCTGACGGATGCCGAGGCGGATCGCCAGCAGGCAGCACGGCTGG
CCGACTCCGCCAAAGATCAGGCGGAAAATCTGATGATAGTGGATCTGTTGCGCAACGACATCGGCCGTGTAGCCCAGCCC
GGTAGCGTGCGCGTGCCATCGCTGTTTGCCATAGAGACGTTTACAGCAGTGCACCACATGGTCAGCACGATCAGCGCCGT
TTTGCCGGCAGATCGCAGCCCCTGCGATCTGCTGCGCGCCTGCTTCCCAGGCGGCTCCATTACCGGCGCGCCTAAGGTGC
GGGCAATGGAAATCATCGAAAGGCTGGAACCGCAGCGTCGCAGTGCCTGGTGCGGCAGTATCGGTTATATCAGCTGCTGC
GGCACGATGGACACCAATATCGCCATTCGCACGCTGCTGGTCGCAGACCGGCACATTCACTGCTCTGTCGGTGGCGGCCT
TGTCGCCGACAGCGATGAAGAAGCGGAATACCAGGAGACGCTGGCTAAAGCGGCCTCGCTGCTGCCTCTGCTGGAACGGC
TGCATGCCTGA

Upstream 100 bases:

>100_bases
TTACGCCATGACGGGGAGTTATGCTAGGATCGCGCCATAAACTCATAACTCACCACGACGCGGGCAGGATGCCGAAGCCG
CGTCGATCGGGAACAGGCGC

Downstream 100 bases:

>100_bases
ATCCCTGACAGAACGTCCGCTCACGTTGCCGGAGTTTATCACCCGTTTCCAACTCTGTTGCCGGAAACCCGCCACGCCAC
CTATCACCGCCGGCAGGCGG

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTMQPQLTALPYRPDAVLDFFTPFAGQPWSILLHSGHSDHPDSRYDILVAAPAVTLVTRDGVTEVRWGETCELRDDDPFA
LVQQQLAAVGMMASPNAELPFQGGALGYFGYDLARGIETLPVLAQQDLPLPDMAIGIYRWAVVADHHRRTVTLVSHDDPT
PILARLTAAPPAPPAPFHLLGPWHANMTSADYGDKFRQVQQHLLVGDCYQVCLSQRFSAPCDGDEWPAFRLLLAHNRAPF
SAFIRLADQTTVLSLSPERFLRLRGGEIQTRPIKGTLPRLTDAEADRQQAARLADSAKDQAENLMIVDLLRNDIGRVAQP
GSVRVPSLFAIETFTAVHHMVSTISAVLPADRSPCDLLRACFPGGSITGAPKVRAMEIIERLEPQRRSAWCGSIGYISCC
GTMDTNIAIRTLLVADRHIHCSVGGGLVADSDEEAEYQETLAKAASLLPLLERLHA

Sequences:

>Translated_456_residues
MTMQPQLTALPYRPDAVLDFFTPFAGQPWSILLHSGHSDHPDSRYDILVAAPAVTLVTRDGVTEVRWGETCELRDDDPFA
LVQQQLAAVGMMASPNAELPFQGGALGYFGYDLARGIETLPVLAQQDLPLPDMAIGIYRWAVVADHHRRTVTLVSHDDPT
PILARLTAAPPAPPAPFHLLGPWHANMTSADYGDKFRQVQQHLLVGDCYQVCLSQRFSAPCDGDEWPAFRLLLAHNRAPF
SAFIRLADQTTVLSLSPERFLRLRGGEIQTRPIKGTLPRLTDAEADRQQAARLADSAKDQAENLMIVDLLRNDIGRVAQP
GSVRVPSLFAIETFTAVHHMVSTISAVLPADRSPCDLLRACFPGGSITGAPKVRAMEIIERLEPQRRSAWCGSIGYISCC
GTMDTNIAIRTLLVADRHIHCSVGGGLVADSDEEAEYQETLAKAASLLPLLERLHA
>Mature_455_residues
TMQPQLTALPYRPDAVLDFFTPFAGQPWSILLHSGHSDHPDSRYDILVAAPAVTLVTRDGVTEVRWGETCELRDDDPFAL
VQQQLAAVGMMASPNAELPFQGGALGYFGYDLARGIETLPVLAQQDLPLPDMAIGIYRWAVVADHHRRTVTLVSHDDPTP
ILARLTAAPPAPPAPFHLLGPWHANMTSADYGDKFRQVQQHLLVGDCYQVCLSQRFSAPCDGDEWPAFRLLLAHNRAPFS
AFIRLADQTTVLSLSPERFLRLRGGEIQTRPIKGTLPRLTDAEADRQQAARLADSAKDQAENLMIVDLLRNDIGRVAQPG
SVRVPSLFAIETFTAVHHMVSTISAVLPADRSPCDLLRACFPGGSITGAPKVRAMEIIERLEPQRRSAWCGSIGYISCCG
TMDTNIAIRTLLVADRHIHCSVGGGLVADSDEEAEYQETLAKAASLLPLLERLHA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=452, Percent_Identity=58.1858407079646, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1787518, Length=408, Percent_Identity=31.8627450980392, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1786809, Length=220, Percent_Identity=24.5454545454545, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082077, Length=218, Percent_Identity=27.0642201834862, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=437, Percent_Identity=31.1212814645309, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=395, Percent_Identity=26.5822784810127, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49913; Mature: 49781

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQPQLTALPYRPDAVLDFFTPFAGQPWSILLHSGHSDHPDSRYDILVAAPAVTLVTRD
CCCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEEECC
GVTEVRWGETCELRDDDPFALVQQQLAAVGMMASPNAELPFQGGALGYFGYDLARGIETL
CCCEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHH
PVLAQQDLPLPDMAIGIYRWAVVADHHRRTVTLVSHDDPTPILARLTAAPPAPPAPFHLL
HHHHCCCCCCCHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHEEECCCCCCCCCEEEE
GPWHANMTSADYGDKFRQVQQHLLVGDCYQVCLSQRFSAPCDGDEWPAFRLLLAHNRAPF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCH
SAFIRLADQTTVLSLSPERFLRLRGGEIQTRPIKGTLPRLTDAEADRQQAARLADSAKDQ
HHHHHHCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AENLMIVDLLRNDIGRVAQPGSVRVPSLFAIETFTAVHHMVSTISAVLPADRSPCDLLRA
HCCEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
CFPGGSITGAPKVRAMEIIERLEPQRRSAWCGSIGYISCCGTMDTNIAIRTLLVADRHIH
HCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCHHEEEEEEECCEEE
CSVGGGLVADSDEEAEYQETLAKAASLLPLLERLHA
EECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMQPQLTALPYRPDAVLDFFTPFAGQPWSILLHSGHSDHPDSRYDILVAAPAVTLVTRD
CCCCCCEECCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEEECC
GVTEVRWGETCELRDDDPFALVQQQLAAVGMMASPNAELPFQGGALGYFGYDLARGIETL
CCCEECCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHH
PVLAQQDLPLPDMAIGIYRWAVVADHHRRTVTLVSHDDPTPILARLTAAPPAPPAPFHLL
HHHHCCCCCCCHHHHHHHHHHHEECCCCEEEEEEECCCCCHHHHEEECCCCCCCCCEEEE
GPWHANMTSADYGDKFRQVQQHLLVGDCYQVCLSQRFSAPCDGDEWPAFRLLLAHNRAPF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCH
SAFIRLADQTTVLSLSPERFLRLRGGEIQTRPIKGTLPRLTDAEADRQQAARLADSAKDQ
HHHHHHCCCCEEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AENLMIVDLLRNDIGRVAQPGSVRVPSLFAIETFTAVHHMVSTISAVLPADRSPCDLLRA
HCCEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
CFPGGSITGAPKVRAMEIIERLEPQRRSAWCGSIGYISCCGTMDTNIAIRTLLVADRHIH
HCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCHHEEEEEEECCEEE
CSVGGGLVADSDEEAEYQETLAKAASLLPLLERLHA
EECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]