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The map label for this gene is putA

Identifier: 85059221

GI number: 85059221

Start: 2094406

End: 2098350

Strand: Reverse

Name: putA

Synonym: SG1243

Alternate gene names: 85059221

Gene position: 2098350-2094406 (Counterclockwise)

Preceding gene: 85059222

Following gene: 85059217

Centisome position: 50.31

GC content: 60.1

Gene sequence:

>3945_bases
ATGGGTACAACCACAATGGGCGTAAAATTAGACGATGAGGCGCGCGAACGCATTAAGCAGGCGGCGCGTCAGCTTGACCG
CACGCCCCACTGGCTCATTAAGCAAGCAATATTCCATTATCTGGACGCGCTGGAACAAGGTGCAACTCCCGGACTACCAC
TGCCGGCAGCAGAAGCCGATGACACGCTGAAAGTGGTGAGCGACGAGCCGCGTCAACCCTTTATCGATCTGGCGGAACAA
ATCTTGCCGCAATCGATCACCCGTGCCGCCGTCACCGCCGCCTGGCGCCGTCCGGAAACCGAGGCGGTACCTTGGTTACT
GGAGCAGGCCCGTCATCCGGCACCGATGGCAGAAACCATTCAGACACTGGCCGGGAAATTAGCCAATCAATTGCGCCATC
AAAAGCGCAGCGGCGGCCGCGCGGGTATAGTGCAAGATCTGCTGCAGGAGTTCTCACTTTCTTCCCAGGAAGGCATAGCG
CTGATGTGCCTGGCCGAAGCGCTGCTGCGGATCCCGGATAAAGCGACGCGGGATGCTTTGATTCGGGACAAGATTAGCAA
CGGCAACTGGCAAACGCACCTGGGCCGTAGTCAATCGCTGTTCGTCAACGCCGCCACCTGGGGTCTTTTGTTCACCGGCA
AACTGGTTGCAACCCATAATGAAGCCAGCCTGTCGCGCTCGCTTAACCGCATTATCGGCAAAAGCGGCGAACCCCTGATC
CGTAAGGGAGTGGATATGGCCATGCGGTTGATGGGCGAGCAATTCGTCACCGGCGAGCACATCGGCGAAGCGCTGGCCAA
CGCGCACCGTCTGGAACAGCAGGGGTTCCGTTATTCCTATGACATGCTGGGTGAAGCCGCACTGACGGAAGAGGATGCCC
AGGCCTACCTGCTTTCCTACCAGCAGGCAATACATGCCATCGGCAAAGCTTCAAGCGGCCGCGGTATCTATGAGGGGCCT
GGGATTTCCATCAAGCTTTCCGCGCTGCACCCTCGCTACTGCCGGGCGCAATATGAACGCGTCATGGCGGAGCTGTATCC
GCGGCTGCTGCGGTTGACTCTGCTGGCGCGACAATATGATATCGGCCTTAATATCGACGCCGAAGAAGCCGACCGGCTGG
AAATTTCCCTCGATTTGCTGGCCCGACTTTGCTTCGAGCCGGCGCTGGCGGGCTGGAACGGCATCGGCTTTGTCATTCAG
GCTTACCAAAAACGCTGCCCGCAGGTCATTGACGAGCTGATAGACCTCGCCAAGCGCAGCCAGCGCCGCCTGATGATTCG
GCTTGTGAAAGGCGCCTATTGGGATAGCGAAATCAAACGCGCGCAAATCGAAGGGCTGGAGGATTACCCGGTCTTTACGC
GCAAAGTCTATACCGATCTCTCTTACCTTGCCTGTGCACGCAAGCTGCTCAGCGTCCCGCATTATATTTATCCGCAATTC
GCCACCCATAACGCCCATACGTTGGCGGCGATTTATCATTTCGCCGGCCAAAACTATTATCCGGGCCAGTATGAGTTCCA
GTGCCTGCACGGCATGGGCGAACCGCTTTATGAGCAAGTCGTAGGCAAAGTCGCCGAGGGCAAGTTAAACCGTCCCTGCC
GCATCTACGCCCCCGTCGGAAGCCACGAAACACTCCTAGCCTACCTGGTACGGCGGCTGTTGGAAAATGGCGCCAATACC
TCATTCGTTAACCGTATCGCCGACAGCGCCGTGCCGCTGGAGCAATTGATAGCCGATCCGGTACAGGAAGTGACCCAGCT
CGCGGTGCGCGAAGGCCGTGCGGGGCTGCCCCATCCGAAGATCCCCCTGCCGCGCGATTTATATGGCGCGCAGCGGCGTA
ATTCTGCCGGGCTGGATCTGGCTAATGAGCATCGTTTGGCCTCCCTGTCGGCCGCATTGCTTAACGTTGAACACCAAACC
TGGCAGGCAGCACCGGTCGTCGTCACCGAGATAGGCGACGGGGCAGTGCAGAAAGTGCTTAATCCGGCGGATCATCGCGA
TGTGGTCGGCGAGTGCCGGCAGGCCTCCTCAGAGGAAGTGGCGCACGCGCTGGCCGCTGCCGTACATCATGGATCACTCT
GGTCTGCCACACCGCCCGCCGATCGCGCTGCGGTGCTAAAAGAAGCCGCCAACCGGCTGGAGACGGACATGCAGCCGCTT
ATCGGCCTTCTGGTACGCGAGGCGGGCAAGAGTTTCAGCAATGCCGTTGCCGAAGTGCGCGAGGCGGTGGATTTTCTGCG
CTACTACGCTTGCCAGATAGCGCAGGATTTCGATAACGACAATTATCGCCCGCTTGGGCCTGTGGTTTGCATCAGTCCAT
GGAACTTCCCGCTGGCGATTTTCCTCGGCCAGATTGCCGCCGCGCTGGCGGCGGGCAACACGGTTCTGGCCAAGCCTGCC
GAGCAAACGCCGCTTATCGCCGCCAGGGCGGTAGCGCTAATGCTGGAGGCCGGCGTGCCTTTGGGAGTATTGCAACTTTT
GCCGGGGGCCGGGGAGACAGTGGGCGCGGCGCTAGTCGCAGACCCGCGCGTACGGGGCGTCATGTTCACCGGCTCGACAC
AGGTAGCCAGACTGCTGCAAACGACTCTCGCTGCACGGTTGGATCCTCAGGGCCGCCCGATACCGCTTATCGCCGAAACC
GGAGGACTGAATGCGATGTTGGTGGACTCTTCGGCGCTAACCGAGCAGGTTATCATCGATGTGGTAACCTCGGCCTTCGA
CAGCGCTGGCCAACGCTGTTCAGCACTACGCCTGCTGTGTATCCAGGAGGACGTCGCCGAGCGGACGCTGCGTATGCTGC
GCGGCGCCATGGCCGAATATACGTTGGGCAACCCCGAACGGCTGGCTACCGATATTGGCCCGGTTATCGATTCTAGCGCA
AAAGCGGCCATCGACAGCCACATAACCGCAATGCGCGAGCGGGGTTATACCGTCTGGCAAACCCCTGCGGCCGAAGCCGC
CGGCGATATCCAGGGCACCTTTGTTCCCTTGACCCTGATCGAGCTCGACAGTATAGAGGCCCTGACACAGGAGGTATTCG
GGCCGGTGTTGCATGTGGTGCGCTATCAGCGCCGCGAGCTGGACAGCATTATCGACCAGATCAACGGCAGCGGTTATGGC
CTCACGCTCGGACTGCATACCCGCATCGATGAAACTATTCAACGTGTCACCGAGCGGGCGCATGTCGGCAATTGCTACAT
TAACCGCAATATCGTCGGCGCCGTTGTGGGCGTCCAGCCTTTCGGCGGCGAAGGGTTATCGGGAACGGGTCCCAAAGCCG
GCGGCCCTCTCTATTTGTACTGTTTACTCTCCCAACGCCGCGATGATGCGCTATTGCCTTCGCTACAGGCACTGGATGCG
GTGCATGCGCCGGATTTCACTCGGCGCGAAATCTTGCAGCAGGCTCACCCTGCTCTGGTCGCCTGGATGGAAACCCACCA
GCCAACGCTTGTCGCCCAATGCCGCCACTTGGGCGAGATTTCCCAGGCGGGCAGCGTTCGCCTGCTTACCGGCCCCACCG
GCGAACAAAATAGTTACCGGCTGCTGCCGCGCGAACACATTTTGTGTCTGGCGGACCAGGATCCCGACCTGCTGCTCCAA
CTGGCGGCAATAACCAGCATTGGCGCACGGGCGCTGTGGGCAGAATCGCCGCAGAGCCGGCGACTCTTCACTACGCTGCC
CGATTCGGTCAGGCAACGTATCACCCTGCTGGCGGACTGGACGCAGGAGGACGTCAGGCTGGATGCGGTGCTATTCCATG
GTGATTCCGATCAATTGCGCAATCTGGCACAAACGCTCTCCAAGCGCCCGGGCCCATTGATAACGGTGCAGGGTAATGCG
CGGGGCGACGGCCAAATCGCGCTGGAACGGCTGTTAATCGAGCGTGCTATCAGCGTCAATACCGCCGCCGCTGGAGGGAA
TGCCAGCCTGATGACCATTGGCTGA

Upstream 100 bases:

>100_bases
ACGGCCGTTAACCATTGATTAAACCTCTCTTTACAGGGTTGCACTAAGTTGCAACATTGGCGATAGTAAGGGCTCATTTG
ACAGGTGGAACGGGAATAGC

Downstream 100 bases:

>100_bases
GAACGCCTCTTGCGCCTGCGCGCCGGTTAGCGCTGTGTTTTCCGCCGGCATTACCGCAGCGCCTTGCGACGCCTGCCATA
CGCCCTGAATACTTTGCAGG

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1314; Mature: 1313

Protein sequence:

>1314_residues
MGTTTMGVKLDDEARERIKQAARQLDRTPHWLIKQAIFHYLDALEQGATPGLPLPAAEADDTLKVVSDEPRQPFIDLAEQ
ILPQSITRAAVTAAWRRPETEAVPWLLEQARHPAPMAETIQTLAGKLANQLRHQKRSGGRAGIVQDLLQEFSLSSQEGIA
LMCLAEALLRIPDKATRDALIRDKISNGNWQTHLGRSQSLFVNAATWGLLFTGKLVATHNEASLSRSLNRIIGKSGEPLI
RKGVDMAMRLMGEQFVTGEHIGEALANAHRLEQQGFRYSYDMLGEAALTEEDAQAYLLSYQQAIHAIGKASSGRGIYEGP
GISIKLSALHPRYCRAQYERVMAELYPRLLRLTLLARQYDIGLNIDAEEADRLEISLDLLARLCFEPALAGWNGIGFVIQ
AYQKRCPQVIDELIDLAKRSQRRLMIRLVKGAYWDSEIKRAQIEGLEDYPVFTRKVYTDLSYLACARKLLSVPHYIYPQF
ATHNAHTLAAIYHFAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGSHETLLAYLVRRLLENGANT
SFVNRIADSAVPLEQLIADPVQEVTQLAVREGRAGLPHPKIPLPRDLYGAQRRNSAGLDLANEHRLASLSAALLNVEHQT
WQAAPVVVTEIGDGAVQKVLNPADHRDVVGECRQASSEEVAHALAAAVHHGSLWSATPPADRAAVLKEAANRLETDMQPL
IGLLVREAGKSFSNAVAEVREAVDFLRYYACQIAQDFDNDNYRPLGPVVCISPWNFPLAIFLGQIAAALAAGNTVLAKPA
EQTPLIAARAVALMLEAGVPLGVLQLLPGAGETVGAALVADPRVRGVMFTGSTQVARLLQTTLAARLDPQGRPIPLIAET
GGLNAMLVDSSALTEQVIIDVVTSAFDSAGQRCSALRLLCIQEDVAERTLRMLRGAMAEYTLGNPERLATDIGPVIDSSA
KAAIDSHITAMRERGYTVWQTPAAEAAGDIQGTFVPLTLIELDSIEALTQEVFGPVLHVVRYQRRELDSIIDQINGSGYG
LTLGLHTRIDETIQRVTERAHVGNCYINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYCLLSQRRDDALLPSLQALDA
VHAPDFTRREILQQAHPALVAWMETHQPTLVAQCRHLGEISQAGSVRLLTGPTGEQNSYRLLPREHILCLADQDPDLLLQ
LAAITSIGARALWAESPQSRRLFTTLPDSVRQRITLLADWTQEDVRLDAVLFHGDSDQLRNLAQTLSKRPGPLITVQGNA
RGDGQIALERLLIERAISVNTAAAGGNASLMTIG

Sequences:

>Translated_1314_residues
MGTTTMGVKLDDEARERIKQAARQLDRTPHWLIKQAIFHYLDALEQGATPGLPLPAAEADDTLKVVSDEPRQPFIDLAEQ
ILPQSITRAAVTAAWRRPETEAVPWLLEQARHPAPMAETIQTLAGKLANQLRHQKRSGGRAGIVQDLLQEFSLSSQEGIA
LMCLAEALLRIPDKATRDALIRDKISNGNWQTHLGRSQSLFVNAATWGLLFTGKLVATHNEASLSRSLNRIIGKSGEPLI
RKGVDMAMRLMGEQFVTGEHIGEALANAHRLEQQGFRYSYDMLGEAALTEEDAQAYLLSYQQAIHAIGKASSGRGIYEGP
GISIKLSALHPRYCRAQYERVMAELYPRLLRLTLLARQYDIGLNIDAEEADRLEISLDLLARLCFEPALAGWNGIGFVIQ
AYQKRCPQVIDELIDLAKRSQRRLMIRLVKGAYWDSEIKRAQIEGLEDYPVFTRKVYTDLSYLACARKLLSVPHYIYPQF
ATHNAHTLAAIYHFAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGSHETLLAYLVRRLLENGANT
SFVNRIADSAVPLEQLIADPVQEVTQLAVREGRAGLPHPKIPLPRDLYGAQRRNSAGLDLANEHRLASLSAALLNVEHQT
WQAAPVVVTEIGDGAVQKVLNPADHRDVVGECRQASSEEVAHALAAAVHHGSLWSATPPADRAAVLKEAANRLETDMQPL
IGLLVREAGKSFSNAVAEVREAVDFLRYYACQIAQDFDNDNYRPLGPVVCISPWNFPLAIFLGQIAAALAAGNTVLAKPA
EQTPLIAARAVALMLEAGVPLGVLQLLPGAGETVGAALVADPRVRGVMFTGSTQVARLLQTTLAARLDPQGRPIPLIAET
GGLNAMLVDSSALTEQVIIDVVTSAFDSAGQRCSALRLLCIQEDVAERTLRMLRGAMAEYTLGNPERLATDIGPVIDSSA
KAAIDSHITAMRERGYTVWQTPAAEAAGDIQGTFVPLTLIELDSIEALTQEVFGPVLHVVRYQRRELDSIIDQINGSGYG
LTLGLHTRIDETIQRVTERAHVGNCYINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYCLLSQRRDDALLPSLQALDA
VHAPDFTRREILQQAHPALVAWMETHQPTLVAQCRHLGEISQAGSVRLLTGPTGEQNSYRLLPREHILCLADQDPDLLLQ
LAAITSIGARALWAESPQSRRLFTTLPDSVRQRITLLADWTQEDVRLDAVLFHGDSDQLRNLAQTLSKRPGPLITVQGNA
RGDGQIALERLLIERAISVNTAAAGGNASLMTIG
>Mature_1313_residues
GTTTMGVKLDDEARERIKQAARQLDRTPHWLIKQAIFHYLDALEQGATPGLPLPAAEADDTLKVVSDEPRQPFIDLAEQI
LPQSITRAAVTAAWRRPETEAVPWLLEQARHPAPMAETIQTLAGKLANQLRHQKRSGGRAGIVQDLLQEFSLSSQEGIAL
MCLAEALLRIPDKATRDALIRDKISNGNWQTHLGRSQSLFVNAATWGLLFTGKLVATHNEASLSRSLNRIIGKSGEPLIR
KGVDMAMRLMGEQFVTGEHIGEALANAHRLEQQGFRYSYDMLGEAALTEEDAQAYLLSYQQAIHAIGKASSGRGIYEGPG
ISIKLSALHPRYCRAQYERVMAELYPRLLRLTLLARQYDIGLNIDAEEADRLEISLDLLARLCFEPALAGWNGIGFVIQA
YQKRCPQVIDELIDLAKRSQRRLMIRLVKGAYWDSEIKRAQIEGLEDYPVFTRKVYTDLSYLACARKLLSVPHYIYPQFA
THNAHTLAAIYHFAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGSHETLLAYLVRRLLENGANTS
FVNRIADSAVPLEQLIADPVQEVTQLAVREGRAGLPHPKIPLPRDLYGAQRRNSAGLDLANEHRLASLSAALLNVEHQTW
QAAPVVVTEIGDGAVQKVLNPADHRDVVGECRQASSEEVAHALAAAVHHGSLWSATPPADRAAVLKEAANRLETDMQPLI
GLLVREAGKSFSNAVAEVREAVDFLRYYACQIAQDFDNDNYRPLGPVVCISPWNFPLAIFLGQIAAALAAGNTVLAKPAE
QTPLIAARAVALMLEAGVPLGVLQLLPGAGETVGAALVADPRVRGVMFTGSTQVARLLQTTLAARLDPQGRPIPLIAETG
GLNAMLVDSSALTEQVIIDVVTSAFDSAGQRCSALRLLCIQEDVAERTLRMLRGAMAEYTLGNPERLATDIGPVIDSSAK
AAIDSHITAMRERGYTVWQTPAAEAAGDIQGTFVPLTLIELDSIEALTQEVFGPVLHVVRYQRRELDSIIDQINGSGYGL
TLGLHTRIDETIQRVTERAHVGNCYINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYCLLSQRRDDALLPSLQALDAV
HAPDFTRREILQQAHPALVAWMETHQPTLVAQCRHLGEISQAGSVRLLTGPTGEQNSYRLLPREHILCLADQDPDLLLQL
AAITSIGARALWAESPQSRRLFTTLPDSVRQRITLLADWTQEDVRLDAVLFHGDSDQLRNLAQTLSKRPGPLITVQGNAR
GDGQIALERLLIERAISVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=30.4157549234136, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI153266822, Length=451, Percent_Identity=29.0465631929047, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI25777724, Length=460, Percent_Identity=30.2173913043478, Blast_Score=170, Evalue=8e-42,
Organism=Homo sapiens, GI25777736, Length=527, Percent_Identity=29.9810246679317, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777734, Length=527, Percent_Identity=29.9810246679317, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238859541, Length=485, Percent_Identity=30.5154639175258, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI25777732, Length=453, Percent_Identity=29.1390728476821, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI12007648, Length=447, Percent_Identity=28.8590604026846, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI25777730, Length=454, Percent_Identity=29.295154185022, Blast_Score=157, Evalue=9e-38,
Organism=Homo sapiens, GI25777728, Length=412, Percent_Identity=30.0970873786408, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=28.1323877068558, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI238814322, Length=470, Percent_Identity=26.1702127659574, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI4507229, Length=414, Percent_Identity=26.8115942028986, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI188035924, Length=464, Percent_Identity=27.3706896551724, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI310128103, Length=464, Percent_Identity=27.3706896551724, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI115387104, Length=462, Percent_Identity=25.3246753246753, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI310128093, Length=464, Percent_Identity=26.9396551724138, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI25777721, Length=427, Percent_Identity=25.9953161592506, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI25952152, Length=447, Percent_Identity=27.2930648769575, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=26.5882352941176, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI25777726, Length=460, Percent_Identity=26.5217391304348, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128091, Length=389, Percent_Identity=28.2776349614396, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI4502043, Length=468, Percent_Identity=26.7094017094017, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI238814371, Length=468, Percent_Identity=26.7094017094017, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI71773324, Length=371, Percent_Identity=26.4150943396226, Blast_Score=107, Evalue=8e-23,
Organism=Homo sapiens, GI73695881, Length=367, Percent_Identity=25.3405994550409, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI73695879, Length=367, Percent_Identity=25.3405994550409, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI310128087, Length=286, Percent_Identity=28.6713286713287, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI206597441, Length=345, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI206597439, Length=345, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI22907049, Length=345, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI301500698, Length=289, Percent_Identity=25.9515570934256, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI310128101, Length=233, Percent_Identity=27.8969957081545, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI310128099, Length=232, Percent_Identity=28.0172413793103, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=334, Percent_Identity=23.3532934131737, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI4557303, Length=333, Percent_Identity=23.4234234234234, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=26.605504587156, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=28.1150159744409, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128097, Length=262, Percent_Identity=27.8625954198473, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=1321, Percent_Identity=71.6881150643452, Blast_Score=1895, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=464, Percent_Identity=30.3879310344828, Blast_Score=174, Evalue=4e-44,
Organism=Escherichia coli, GI1787715, Length=454, Percent_Identity=30.3964757709251, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1787684, Length=470, Percent_Identity=30, Blast_Score=156, Evalue=7e-39,
Organism=Escherichia coli, GI1787558, Length=432, Percent_Identity=29.6296296296296, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1788042, Length=481, Percent_Identity=29.1060291060291, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI1786504, Length=475, Percent_Identity=26.7368421052632, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI87081896, Length=430, Percent_Identity=28.8372093023256, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87082295, Length=465, Percent_Identity=27.9569892473118, Blast_Score=133, Evalue=1e-31,
Organism=Escherichia coli, GI87081926, Length=429, Percent_Identity=23.5431235431235, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1787653, Length=392, Percent_Identity=22.9591836734694, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534447, Length=480, Percent_Identity=29.7916666666667, Blast_Score=179, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI133930964, Length=470, Percent_Identity=27.8723404255319, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25144435, Length=459, Percent_Identity=28.7581699346405, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI115532534, Length=378, Percent_Identity=31.2169312169312, Blast_Score=153, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=493, Percent_Identity=28.6004056795132, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=29.4117647058824, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17562198, Length=458, Percent_Identity=27.7292576419214, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=445, Percent_Identity=26.9662921348315, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25143874, Length=417, Percent_Identity=27.3381294964029, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25143876, Length=417, Percent_Identity=27.3381294964029, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71986308, Length=449, Percent_Identity=27.3942093541203, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17551164, Length=434, Percent_Identity=25.8064516129032, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71995606, Length=442, Percent_Identity=25.3393665158371, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17534119, Length=483, Percent_Identity=24.0165631469979, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71995613, Length=399, Percent_Identity=24.5614035087719, Blast_Score=108, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=321, Percent_Identity=28.0373831775701, Blast_Score=106, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=331, Percent_Identity=24.4712990936556, Blast_Score=90, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=331, Percent_Identity=24.4712990936556, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=331, Percent_Identity=24.4712990936556, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=332, Percent_Identity=25.6024096385542, Blast_Score=86, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325196, Length=464, Percent_Identity=30.3879310344828, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=486, Percent_Identity=30.6584362139918, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=28, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320917, Length=452, Percent_Identity=30.0884955752212, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=464, Percent_Identity=29.7413793103448, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=463, Percent_Identity=28.9416846652268, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=467, Percent_Identity=25.6959314775161, Blast_Score=131, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=358, Percent_Identity=26.2569832402235, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323757, Length=328, Percent_Identity=25.3048780487805, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650465, Length=456, Percent_Identity=27.8508771929825, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24668425, Length=485, Percent_Identity=26.3917525773196, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668417, Length=485, Percent_Identity=26.3917525773196, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668413, Length=485, Percent_Identity=26.3917525773196, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129399, Length=459, Percent_Identity=29.6296296296296, Blast_Score=156, Evalue=9e-38,
Organism=Drosophila melanogaster, GI281362580, Length=453, Percent_Identity=26.4900662251656, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI62472918, Length=453, Percent_Identity=26.4900662251656, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI62472926, Length=453, Percent_Identity=26.4900662251656, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI62472936, Length=453, Percent_Identity=26.4900662251656, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21356737, Length=453, Percent_Identity=26.4900662251656, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24585660, Length=563, Percent_Identity=25.7548845470693, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666674, Length=457, Percent_Identity=28.4463894967177, Blast_Score=144, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571802, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28571800, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28571806, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28571798, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28571796, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28571794, Length=485, Percent_Identity=25.7731958762887, Blast_Score=127, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28574525, Length=500, Percent_Identity=27, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24638878, Length=427, Percent_Identity=25.2927400468384, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24638876, Length=427, Percent_Identity=25.2927400468384, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360299, Length=377, Percent_Identity=23.8726790450928, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360297, Length=377, Percent_Identity=23.8726790450928, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360295, Length=377, Percent_Identity=23.8726790450928, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24586250, Length=377, Percent_Identity=23.8726790450928, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360301, Length=376, Percent_Identity=23.936170212766, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45552499, Length=377, Percent_Identity=23.0769230769231, Blast_Score=85, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281360303, Length=376, Percent_Identity=23.1382978723404, Blast_Score=84, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 143599; Mature: 143468

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTTMGVKLDDEARERIKQAARQLDRTPHWLIKQAIFHYLDALEQGATPGLPLPAAEAD
CCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DTLKVVSDEPRQPFIDLAEQILPQSITRAAVTAAWRRPETEAVPWLLEQARHPAPMAETI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
QTLAGKLANQLRHQKRSGGRAGIVQDLLQEFSLSSQEGIALMCLAEALLRIPDKATRDAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
IRDKISNGNWQTHLGRSQSLFVNAATWGLLFTGKLVATHNEASLSRSLNRIIGKSGEPLI
HHHHCCCCCCEECCCCCCEEEEEHHHHHHHEECEEEEECCHHHHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGEHIGEALANAHRLEQQGFRYSYDMLGEAALTEEDAQAYLLSY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCHHHHHHHHHHH
QQAIHAIGKASSGRGIYEGPGISIKLSALHPRYCRAQYERVMAELYPRLLRLTLLARQYD
HHHHHHHCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLEISLDLLARLCFEPALAGWNGIGFVIQAYQKRCPQVIDELIDLAKRS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLMIRLVKGAYWDSEIKRAQIEGLEDYPVFTRKVYTDLSYLACARKLLSVPHYIYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
ATHNAHTLAAIYHFAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCC
SHETLLAYLVRRLLENGANTSFVNRIADSAVPLEQLIADPVQEVTQLAVREGRAGLPHPK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPLPRDLYGAQRRNSAGLDLANEHRLASLSAALLNVEHQTWQAAPVVVTEIGDGAVQKVL
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHC
NPADHRDVVGECRQASSEEVAHALAAAVHHGSLWSATPPADRAAVLKEAANRLETDMQPL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGLLVREAGKSFSNAVAEVREAVDFLRYYACQIAQDFDNDNYRPLGPVVCISPWNFPLAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHH
FLGQIAAALAAGNTVLAKPAEQTPLIAARAVALMLEAGVPLGVLQLLPGAGETVGAALVA
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCHHHEE
DPRVRGVMFTGSTQVARLLQTTLAARLDPQGRPIPLIAETGGLNAMLVDSSALTEQVIID
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHH
VVTSAFDSAGQRCSALRLLCIQEDVAERTLRMLRGAMAEYTLGNPERLATDIGPVIDSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCH
KAAIDSHITAMRERGYTVWQTPAAEAAGDIQGTFVPLTLIELDSIEALTQEVFGPVLHVV
HHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHH
RYQRRELDSIIDQINGSGYGLTLGLHTRIDETIQRVTERAHVGNCYINRNIVGAVVGVQP
HHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCC
FGGEGLSGTGPKAGGPLYLYCLLSQRRDDALLPSLQALDAVHAPDFTRREILQQAHPALV
CCCCCCCCCCCCCCCCEEEEEEHHCCCCCHHCCHHHHHHHHCCCCHHHHHHHHHHCHHHH
AWMETHQPTLVAQCRHLGEISQAGSVRLLTGPTGEQNSYRLLPREHILCLADQDPDLLLQ
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHHHHH
LAAITSIGARALWAESPQSRRLFTTLPDSVRQRITLLADWTQEDVRLDAVLFHGDSDQLR
HHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHH
NLAQTLSKRPGPLITVQGNARGDGQIALERLLIERAISVNTAAAGGNASLMTIG
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
GTTTMGVKLDDEARERIKQAARQLDRTPHWLIKQAIFHYLDALEQGATPGLPLPAAEAD
CCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DTLKVVSDEPRQPFIDLAEQILPQSITRAAVTAAWRRPETEAVPWLLEQARHPAPMAETI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
QTLAGKLANQLRHQKRSGGRAGIVQDLLQEFSLSSQEGIALMCLAEALLRIPDKATRDAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
IRDKISNGNWQTHLGRSQSLFVNAATWGLLFTGKLVATHNEASLSRSLNRIIGKSGEPLI
HHHHCCCCCCEECCCCCCEEEEEHHHHHHHEECEEEEECCHHHHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGEHIGEALANAHRLEQQGFRYSYDMLGEAALTEEDAQAYLLSY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCHHHHHHHHHHH
QQAIHAIGKASSGRGIYEGPGISIKLSALHPRYCRAQYERVMAELYPRLLRLTLLARQYD
HHHHHHHCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLEISLDLLARLCFEPALAGWNGIGFVIQAYQKRCPQVIDELIDLAKRS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLMIRLVKGAYWDSEIKRAQIEGLEDYPVFTRKVYTDLSYLACARKLLSVPHYIYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
ATHNAHTLAAIYHFAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEECCC
SHETLLAYLVRRLLENGANTSFVNRIADSAVPLEQLIADPVQEVTQLAVREGRAGLPHPK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IPLPRDLYGAQRRNSAGLDLANEHRLASLSAALLNVEHQTWQAAPVVVTEIGDGAVQKVL
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHC
NPADHRDVVGECRQASSEEVAHALAAAVHHGSLWSATPPADRAAVLKEAANRLETDMQPL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGLLVREAGKSFSNAVAEVREAVDFLRYYACQIAQDFDNDNYRPLGPVVCISPWNFPLAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHH
FLGQIAAALAAGNTVLAKPAEQTPLIAARAVALMLEAGVPLGVLQLLPGAGETVGAALVA
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCHHHEE
DPRVRGVMFTGSTQVARLLQTTLAARLDPQGRPIPLIAETGGLNAMLVDSSALTEQVIID
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHH
VVTSAFDSAGQRCSALRLLCIQEDVAERTLRMLRGAMAEYTLGNPERLATDIGPVIDSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCH
KAAIDSHITAMRERGYTVWQTPAAEAAGDIQGTFVPLTLIELDSIEALTQEVFGPVLHVV
HHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHH
RYQRRELDSIIDQINGSGYGLTLGLHTRIDETIQRVTERAHVGNCYINRNIVGAVVGVQP
HHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCC
FGGEGLSGTGPKAGGPLYLYCLLSQRRDDALLPSLQALDAVHAPDFTRREILQQAHPALV
CCCCCCCCCCCCCCCCEEEEEEHHCCCCCHHCCHHHHHHHHCCCCHHHHHHHHHHCHHHH
AWMETHQPTLVAQCRHLGEISQAGSVRLLTGPTGEQNSYRLLPREHILCLADQDPDLLLQ
HHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHHHHH
LAAITSIGARALWAESPQSRRLFTTLPDSVRQRITLLADWTQEDVRLDAVLFHGDSDQLR
HHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHH
NLAQTLSKRPGPLITVQGNARGDGQIALERLLIERAISVNTAAAGGNASLMTIG
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]