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The map label for this gene is cdd

Identifier: 85058946

GI number: 85058946

Start: 1593361

End: 1594290

Strand: Reverse

Name: cdd

Synonym: SG0968

Alternate gene names: 85058946

Gene position: 1594290-1593361 (Counterclockwise)

Preceding gene: 85058947

Following gene: 85058945

Centisome position: 38.22

GC content: 61.08

Gene sequence:

>930_bases
ATGATTGCTCGTTTTGCACCGGCACTGGCCGCGGTTAGCCCTGCGTTACACACTGCCCTGGCGCCGCTGCTCGATCATCA
CGCCTTCGCCGGCTGGCTGAGCGCTCCTCAGGTTAAGGAACTCATGCAGGCCGGCGGCCTGGACGAAGACGCGTTATGCT
TCACGCTGCTGCCGCTCGCCGCCGCCTATGCCGTCACACCGCTCTCCCATTTTAACGTCGGCGCTATCGCGTGCGGCATC
AGCGGCAATCTCTATTTCGGCGCCAATATGGAATTCCTCGCCGCGCCGCTGCAGCAAACGGTGCATGCGGAACAAAGCGC
GATTGCCCACGCCTGGCTGCGTGGTGAAAAACGACTGCGGGCGCTAACGGTTAACTATACCCCCTGCGGCCATTGCCGGC
AGTTTATGAATGAATTGAACAGCGGCACCGATTTGATTATCTGCCTGCCCGAGCGTTCCGCCGCAACGCTCGCCAGCTAT
CTTCCCGATGCGTTCGGACCGCGCGATCTCGCTATTCAAAGCCTGTTGCTGGATGAAATTGACCACGCTTTCGCCGCCGC
GGCATGGCTGGACCATGATCTATCCGCGCCCTCCCCCGACGACAATGATCCTTTGGTTAGCACAGCGCTGGATGCGGCCA
GCCGGAGCCATGCGCCCTACAGTCAAAGCCACAGCGGCGTCGCGCTGCAGACGCAGGATGGCTGCGTCTACGCGGGACGC
TATGCGGAAAACGCCGCGTTCAATCCCAGCCTGCCGCCGCTGCAAACAGCGCTCATTCTGATGAACGCCGCTGGCGCCGA
TGACCGACAGATTAGACGAGCAGTATTGGCGGAGCGGCAAAATGCACCGATAACGCAGTGGCCTGCAACGAACGCAACCC
TTGCCGCGCTGGGCTGCCATGAGGTACACCATCTCAGTCTTTCTCTGTGA

Upstream 100 bases:

>100_bases
TCAAATTACTCAGTTAATTGTTAACGATAAGATATAGATCGTAGTTAATTACGTTATCCCTGTTTACAATGATTGCCTGC
CCAATGTACAGAGACCCCTT

Downstream 100 bases:

>100_bases
CCCCCGACGCGTCGACAGTCCGGTAACGGGCGTATTTAGCGGAGCGCAGTAAAAAAATATATTACAACTCCGGCCGGACA
ATCACTGCCGTGATCTTTTA

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIARFAPALAAVSPALHTALAPLLDHHAFAGWLSAPQVKELMQAGGLDEDALCFTLLPLAAAYAVTPLSHFNVGAIACGI
SGNLYFGANMEFLAAPLQQTVHAEQSAIAHAWLRGEKRLRALTVNYTPCGHCRQFMNELNSGTDLIICLPERSAATLASY
LPDAFGPRDLAIQSLLLDEIDHAFAAAAWLDHDLSAPSPDDNDPLVSTALDAASRSHAPYSQSHSGVALQTQDGCVYAGR
YAENAAFNPSLPPLQTALILMNAAGADDRQIRRAVLAERQNAPITQWPATNATLAALGCHEVHHLSLSL

Sequences:

>Translated_309_residues
MIARFAPALAAVSPALHTALAPLLDHHAFAGWLSAPQVKELMQAGGLDEDALCFTLLPLAAAYAVTPLSHFNVGAIACGI
SGNLYFGANMEFLAAPLQQTVHAEQSAIAHAWLRGEKRLRALTVNYTPCGHCRQFMNELNSGTDLIICLPERSAATLASY
LPDAFGPRDLAIQSLLLDEIDHAFAAAAWLDHDLSAPSPDDNDPLVSTALDAASRSHAPYSQSHSGVALQTQDGCVYAGR
YAENAAFNPSLPPLQTALILMNAAGADDRQIRRAVLAERQNAPITQWPATNATLAALGCHEVHHLSLSL
>Mature_309_residues
MIARFAPALAAVSPALHTALAPLLDHHAFAGWLSAPQVKELMQAGGLDEDALCFTLLPLAAAYAVTPLSHFNVGAIACGI
SGNLYFGANMEFLAAPLQQTVHAEQSAIAHAWLRGEKRLRALTVNYTPCGHCRQFMNELNSGTDLIICLPERSAATLASY
LPDAFGPRDLAIQSLLLDEIDHAFAAAAWLDHDLSAPSPDDNDPLVSTALDAASRSHAPYSQSHSGVALQTQDGCVYAGR
YAENAAFNPSLPPLQTALILMNAAGADDRQIRRAVLAERQNAPITQWPATNATLAALGCHEVHHLSLSL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=308, Percent_Identity=59.7402597402597, Blast_Score=326, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_SODGM (Q2NUD2)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454648.1
- HSSP:   P56389
- ProteinModelPortal:   Q2NUD2
- SMR:   Q2NUD2
- STRING:   Q2NUD2
- GeneID:   3867095
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0968
- NMPDR:   fig|343509.6.peg.2011
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- PhylomeDB:   Q2NUD2
- ProtClustDB:   PRK09027
- BioCyc:   SGLO343509:SG0968-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 32837; Mature: 32837

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARFAPALAAVSPALHTALAPLLDHHAFAGWLSAPQVKELMQAGGLDEDALCFTLLPLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
AAYAVTPLSHFNVGAIACGISGNLYFGANMEFLAAPLQQTVHAEQSAIAHAWLRGEKRLR
HHHHHCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ALTVNYTPCGHCRQFMNELNSGTDLIICLPERSAATLASYLPDAFGPRDLAIQSLLLDEI
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DHAFAAAAWLDHDLSAPSPDDNDPLVSTALDAASRSHAPYSQSHSGVALQTQDGCVYAGR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEECC
YAENAAFNPSLPPLQTALILMNAAGADDRQIRRAVLAERQNAPITQWPATNATLAALGCH
CCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHH
EVHHLSLSL
HHHEEEECC
>Mature Secondary Structure
MIARFAPALAAVSPALHTALAPLLDHHAFAGWLSAPQVKELMQAGGLDEDALCFTLLPLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
AAYAVTPLSHFNVGAIACGISGNLYFGANMEFLAAPLQQTVHAEQSAIAHAWLRGEKRLR
HHHHHCCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ALTVNYTPCGHCRQFMNELNSGTDLIICLPERSAATLASYLPDAFGPRDLAIQSLLLDEI
EEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DHAFAAAAWLDHDLSAPSPDDNDPLVSTALDAASRSHAPYSQSHSGVALQTQDGCVYAGR
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEECC
YAENAAFNPSLPPLQTALILMNAAGADDRQIRRAVLAERQNAPITQWPATNATLAALGCH
CCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHH
EVHHLSLSL
HHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA