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The map label for this gene is mtnP [H]

Identifier: 84623421

GI number: 84623421

Start: 1949396

End: 1950148

Strand: Direct

Name: mtnP [H]

Synonym: XOO_1764

Alternate gene names: 84623421

Gene position: 1949396-1950148 (Clockwise)

Preceding gene: 84623420

Following gene: 84623422

Centisome position: 39.46

GC content: 64.28

Gene sequence:

>753_bases
GTGTCCGCAAATTCCATCGCATTGGCCGTCATCGGCGGCACTGGTGTCTACACGCTCGCGCAGCTGGACGATGTGCAGTC
GCACCACGTCCCAACGCCCTATGGCGCGCCGTCCGGGCCGATCCGCGTCGGCATGCTGCTTGGCCATCGCGTCGCCTTCC
TGGCCCGGCATGGCGAAGGGCATTCGCTGCCGCCGCACAAGGTCAATTACCGCGCAAACATCGCTGCACTGCAGCAAATC
GGTGCCTCGCGCGTGCTGGCGCTCAACACCGTGGGCGGCATCACCGAACAGTTCGGACCACGCGTGTTAGCCTGCCCGGA
CCAGCTGATCGACTACACCTGGGGTCGTGTGTCCACCTTCTGCGAAGAGCCAGGCAGCGAGGTGCAGCACGTGGATTTCG
GCCATCCGTATTCGCCGATGTTTCGCAGCAAGGTGATTGCGGCAGCCAACGTGACCGGCGTCACGATGGTGGCGGGCGGT
TGCTACGGTGCGACACAAGGACCACGGCTGGAAACGATTGCAGAGATCGCACGCATGCGCCGCGATGGCTGCGATCTGGT
CGGCATGACCGGCATGCCCGAAGCCGGCCTGTCGCGCGAAAAAGGCCTGGAATATGCGTGTCTGGCGATTGTGGCCAATT
GGGCGGCCGGTTGCGGCGACGCCCAGGAAATCACCATGGCCGAGGTGTTGGCCAATGTCGATGCCGCATCGTCCGGCTTG
CCCGAGCTGATTGGCGAACTTGCACGCGGGTGA

Upstream 100 bases:

>100_bases
GCGATGAAGCAGTAACCCGCCGTTTTCCGCTCGCAGACGTGCGAGCTGCCGAGCGCGCCTTGCTGCGCGCACCGTCGTTG
ATTTGTTGCAGAGGTCGGTT

Downstream 100 bases:

>100_bases
TTGTCATCGGGGCATAAGCTTTGCATACTCGGCGCGTACGCACGCCGTACACCACCCATTCATTATTGCAAAGGTCTCGC
ATCACCATGCCGAACGGTAC

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSANSIALAVIGGTGVYTLAQLDDVQSHHVPTPYGAPSGPIRVGMLLGHRVAFLARHGEGHSLPPHKVNYRANIAALQQI
GASRVLALNTVGGITEQFGPRVLACPDQLIDYTWGRVSTFCEEPGSEVQHVDFGHPYSPMFRSKVIAAANVTGVTMVAGG
CYGATQGPRLETIAEIARMRRDGCDLVGMTGMPEAGLSREKGLEYACLAIVANWAAGCGDAQEITMAEVLANVDAASSGL
PELIGELARG

Sequences:

>Translated_250_residues
MSANSIALAVIGGTGVYTLAQLDDVQSHHVPTPYGAPSGPIRVGMLLGHRVAFLARHGEGHSLPPHKVNYRANIAALQQI
GASRVLALNTVGGITEQFGPRVLACPDQLIDYTWGRVSTFCEEPGSEVQHVDFGHPYSPMFRSKVIAAANVTGVTMVAGG
CYGATQGPRLETIAEIARMRRDGCDLVGMTGMPEAGLSREKGLEYACLAIVANWAAGCGDAQEITMAEVLANVDAASSGL
PELIGELARG
>Mature_249_residues
SANSIALAVIGGTGVYTLAQLDDVQSHHVPTPYGAPSGPIRVGMLLGHRVAFLARHGEGHSLPPHKVNYRANIAALQQIG
ASRVLALNTVGGITEQFGPRVLACPDQLIDYTWGRVSTFCEEPGSEVQHVDFGHPYSPMFRSKVIAAANVTGVTMVAGGC
YGATQGPRLETIAEIARMRRDGCDLVGMTGMPEAGLSREKGLEYACLAIVANWAAGCGDAQEITMAEVLANVDAASSGLP
ELIGELARG

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=246, Percent_Identity=29.2682926829268, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71980569, Length=255, Percent_Identity=33.7254901960784, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323045, Length=246, Percent_Identity=32.520325203252, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221459247, Length=242, Percent_Identity=32.2314049586777, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20130079, Length=254, Percent_Identity=31.496062992126, Blast_Score=117, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 26179; Mature: 26048

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANSIALAVIGGTGVYTLAQLDDVQSHHVPTPYGAPSGPIRVGMLLGHRVAFLARHGEG
CCCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHEECCCC
HSLPPHKVNYRANIAALQQIGASRVLALNTVGGITEQFGPRVLACPDQLIDYTWGRVSTF
CCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHCCHHHHHCCEEEECCHHHHHHHHHHHHHH
CEEPGSEVQHVDFGHPYSPMFRSKVIAAANVTGVTMVAGGCYGATQGPRLETIAEIARMR
HHCCCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
RDGCDLVGMTGMPEAGLSREKGLEYACLAIVANWAAGCGDAQEITMAEVLANVDAASSGL
HCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
PELIGELARG
HHHHHHHHCC
>Mature Secondary Structure 
SANSIALAVIGGTGVYTLAQLDDVQSHHVPTPYGAPSGPIRVGMLLGHRVAFLARHGEG
CCCCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHEECCCC
HSLPPHKVNYRANIAALQQIGASRVLALNTVGGITEQFGPRVLACPDQLIDYTWGRVSTF
CCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHCCHHHHHCCEEEECCHHHHHHHHHHHHHH
CEEPGSEVQHVDFGHPYSPMFRSKVIAAANVTGVTMVAGGCYGATQGPRLETIAEIARMR
HHCCCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
RDGCDLVGMTGMPEAGLSREKGLEYACLAIVANWAAGCGDAQEITMAEVLANVDAASSGL
HCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
PELIGELARG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12533478 [H]