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The map label for this gene is ruvA [H]

Identifier: 84623202

GI number: 84623202

Start: 1701215

End: 1701799

Strand: Direct

Name: ruvA [H]

Synonym: XOO_1545

Alternate gene names: 84623202

Gene position: 1701215-1701799 (Clockwise)

Preceding gene: 84623201

Following gene: 84623203

Centisome position: 34.44

GC content: 66.84

Gene sequence:

>585_bases
ATGATCGGCCGTCTGCGCGGGATCCTGGCCTACAAGCAGCCGCCGTGGCTGGTGATCGACGTGGGCGGGGTGGGGTACGA
GCTGGAGGCGCCGATGAGCACCTTCTACGACCTGCCCGATGTCGGTCGCGACGTGATCCTGTTTACCCATTACGCGCAAA
AGGAAGACAGCGTGTCGTTGTATGGCTTCCTGCGCGAGGGCGAGCGGCGGCTGTTCCGCGACGTGCAGAAGGTCACCGGT
ATCGGTGCCAAGATTGCGCTGGCGGTGTTGTCTGGCGTGACCGTGGACGAATTCGCCCGCTTGATCACCAGTGGCGACAT
CACCGCGCTGACCCGCATCCCCGGCATCGGCAAGAAGACGGCCGAGCGCATGGTGGTGGAGCTGCGCGACCGCGCGGCCG
ACTTCAGCAGCGGCGCGCCGATCACCGGCCAACTGGGGCCGGATGCCATCTCCGAAGCCACCGTGGCCTTGCAGCAGTTG
GGCTACAAGCCTGCCGAGGCTGCCCGCATGGCGCGCGATGCCGGTGCAGAAGGCGGTGAGGTGGCCACGGTCATTCGCAA
GGCCCTGCAAGCCGCGCTGCGCTGA

Upstream 100 bases:

>100_bases
TGCCGCTTCGGCGGTGCGCAGCCCTCGTCAACGGCAGTGAGGAAGTTTGCCAATCCCGAATGCCGAATCCCGAATCCCGG
CACCGCCACGCCGGTGCCCA

Downstream 100 bases:

>100_bases
GCGCAGCCGCCCCATCACTGCGCTGCTGCCAAGCGGGCGCGGCCGGCACTCGGAATCGGCAGGGGCGGCTCGTACACTGC
GCATCCTTGCCCGCGGCCAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQL
GYKPAEAARMARDAGAEGGEVATVIRKALQAALR

Sequences:

>Translated_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQL
GYKPAEAARMARDAGAEGGEVATVIRKALQAALR
>Mature_194_residues
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTG
IGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQL
GYKPAEAARMARDAGAEGGEVATVIRKALQAALR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=46.8599033816425, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20848; Mature: 20848

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHH
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQLGYKPAEAARMARDAGAEGGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
VATVIRKALQAALR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSL
CCCCHHHHHEECCCCEEEEECCCCCEECCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHH
YGFLREGERRLFRDVQKVTGIGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHH
AERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQLGYKPAEAARMARDAGAEGGE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
VATVIRKALQAALR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]