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The map label for this gene is cusC [H]

Identifier: 84623105

GI number: 84623105

Start: 1576800

End: 1578269

Strand: Direct

Name: cusC [H]

Synonym: XOO_1448

Alternate gene names: 84623105

Gene position: 1576800-1578269 (Clockwise)

Preceding gene: 84623102

Following gene: 84623106

Centisome position: 31.92

GC content: 66.26

Gene sequence:

>1470_bases
ATGATTCCACAAATTATTCCGCATCGTTGGTCTTGCGTGTGCCTGGTTGCCGCCAGTGCGGTGCTGGCGGCTGGGTGCTC
GCTCACGCCGGCCTACCAGCGCCCGGCGGTCAGCGTGCCGGCCACGTTCGGCAGTCCGCAGGCTGCATCCGCGCCGGCAT
CCGATCGGACCGACGCCAACGCGACGACCACCGTCGCTTTGAACGAACAAGCGCGCGCGTTCTTGCAGCGCTTCGCACCA
GACCGCGACCTGCGGCCTCTGGTTGAACGTGCGTTGGCGCACAACGGCGATTTCCGCCGCGCTGCGTTGCAGGTAGAGCA
GGCGCGTGCGCACTCCGGTATCGCGCAGGCGTCGCGACTGCCGGCGCTCGCCGTCGGCGCACAGCAGCTCCGGCAACATT
TCGACAACCCGGCGCTGGATGCGCGGTACCAGCAGGACCTGGTGATTGCCAATGCCGGGATCGGCAATTTCGAAGTGGAT
TTCTTTGGCAAGCTGCAGGCGATGTCCGAGGCCGCACGGCAGCGTTACCTGGCCAGCACCTACGGCCGCGATGCCGCGCG
TGGTGCCCTGATTGCTGAGGTGCTGCGTGCCTACACCGCCGAGCGAACCACTGCGCAGGCGCTGCAACAGCTGCAATCGC
TCGATGCCGACAGCGCTGCGTTGCTTGCCATTGCCGAGCGGCACTATCAGGTGGGGCTGATTGCGCGCGACGAGCGCGAT
GCGCAGCGCCGTCAGGCCGATCAGGCCCATGTGGCGGCCTTGCAGGGCAACGACAATCACGCTGCGGCGGTGCGTGCGCT
GCAGCTGCTGGTCGGCTACGACAGCACGCCGGTACCCGGCGATCTGCAGGGTCTGATCGCTGCTGATACGCCTGCCAGTG
CCTGGCGCGCCCTGGATTCGTCGCTGTTGCTGCAACGCCCGGACATCCAGCAGGCCGAGCTGGAGTTGCGCGCGGCCAAT
GCCGATATCGGCGCGGCGCGTGCGGCGTTTTTTCCGTCGATCACCTTGAGCAGCAGCGTGGGCACTGCCAGCGACGGATT
GAACGGTTTGTTTTCTGCAGGCCACGGCTTGTGGAGCTTCATGCCGCAACTGAATCTGCCGTTGTTCGATGGTGGCCGTA
ACCGCGCCAATCTGGAGCTGGCGCAGGTGCGCAAACGCGCCGATGTCGTCGCCTACGAGCAGGTAATCGAGTCTGCATTT
CGTGAGGTCGCCAACGCGCTCGACGCGCACGCCACCTTGTCGCAGGCCGAGCCGCGCGCGCGTGAGCAGGTCGAACGCGA
GCAACTGCGTCTTGCGCGAATGCACGCGCGCGTGGATGCCGGTCTGGAAGACCGCAGCGCGCTGCTGGCCGAGCGTACGC
GCATCGCCCAGACCGAACTCGATTACCTGGACACCGCACGTCAGCGCGTGCTGAGCCGTATTGCGCTGTTTCAGGCGTTC
TACGGCGTGCGCCTGCCCACCGCTTCCTGA

Upstream 100 bases:

>100_bases
GTTGCCCTGTCGTCTCGATCAAATCTGGATAATTCCCGAAAACAACCTGGACGCTGCGGGTCGAGGATGTCGGTCGAGAT
TGGCTCTGTGCTCCGACATC

Downstream 100 bases:

>100_bases
CTTCCGCCGGAGACTTCCGATGAATGCAACGTCCTTCAATCGCCTGCGTGGCACCCGTGCCGTTCGCACCAGCGTCCTCG
CCTGCATGACCGCCATTCCG

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIPQIIPHRWSCVCLVAASAVLAAGCSLTPAYQRPAVSVPATFGSPQAASAPASDRTDANATTTVALNEQARAFLQRFAP
DRDLRPLVERALAHNGDFRRAALQVEQARAHSGIAQASRLPALAVGAQQLRQHFDNPALDARYQQDLVIANAGIGNFEVD
FFGKLQAMSEAARQRYLASTYGRDAARGALIAEVLRAYTAERTTAQALQQLQSLDADSAALLAIAERHYQVGLIARDERD
AQRRQADQAHVAALQGNDNHAAAVRALQLLVGYDSTPVPGDLQGLIAADTPASAWRALDSSLLLQRPDIQQAELELRAAN
ADIGAARAAFFPSITLSSSVGTASDGLNGLFSAGHGLWSFMPQLNLPLFDGGRNRANLELAQVRKRADVVAYEQVIESAF
REVANALDAHATLSQAEPRAREQVEREQLRLARMHARVDAGLEDRSALLAERTRIAQTELDYLDTARQRVLSRIALFQAF
YGVRLPTAS

Sequences:

>Translated_489_residues
MIPQIIPHRWSCVCLVAASAVLAAGCSLTPAYQRPAVSVPATFGSPQAASAPASDRTDANATTTVALNEQARAFLQRFAP
DRDLRPLVERALAHNGDFRRAALQVEQARAHSGIAQASRLPALAVGAQQLRQHFDNPALDARYQQDLVIANAGIGNFEVD
FFGKLQAMSEAARQRYLASTYGRDAARGALIAEVLRAYTAERTTAQALQQLQSLDADSAALLAIAERHYQVGLIARDERD
AQRRQADQAHVAALQGNDNHAAAVRALQLLVGYDSTPVPGDLQGLIAADTPASAWRALDSSLLLQRPDIQQAELELRAAN
ADIGAARAAFFPSITLSSSVGTASDGLNGLFSAGHGLWSFMPQLNLPLFDGGRNRANLELAQVRKRADVVAYEQVIESAF
REVANALDAHATLSQAEPRAREQVEREQLRLARMHARVDAGLEDRSALLAERTRIAQTELDYLDTARQRVLSRIALFQAF
YGVRLPTAS
>Mature_489_residues
MIPQIIPHRWSCVCLVAASAVLAAGCSLTPAYQRPAVSVPATFGSPQAASAPASDRTDANATTTVALNEQARAFLQRFAP
DRDLRPLVERALAHNGDFRRAALQVEQARAHSGIAQASRLPALAVGAQQLRQHFDNPALDARYQQDLVIANAGIGNFEVD
FFGKLQAMSEAARQRYLASTYGRDAARGALIAEVLRAYTAERTTAQALQQLQSLDADSAALLAIAERHYQVGLIARDERD
AQRRQADQAHVAALQGNDNHAAAVRALQLLVGYDSTPVPGDLQGLIAADTPASAWRALDSSLLLQRPDIQQAELELRAAN
ADIGAARAAFFPSITLSSSVGTASDGLNGLFSAGHGLWSFMPQLNLPLFDGGRNRANLELAQVRKRADVVAYEQVIESAF
REVANALDAHATLSQAEPRAREQVEREQLRLARMHARVDAGLEDRSALLAERTRIAQTELDYLDTARQRVLSRIALFQAF
YGVRLPTAS

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=496, Percent_Identity=36.0887096774194, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI2367348, Length=185, Percent_Identity=30.8108108108108, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52858; Mature: 52858

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPQIIPHRWSCVCLVAASAVLAAGCSLTPAYQRPAVSVPATFGSPQAASAPASDRTDAN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATTTVALNEQARAFLQRFAPDRDLRPLVERALAHNGDFRRAALQVEQARAHSGIAQASRL
CEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PALAVGAQQLRQHFDNPALDARYQQDLVIANAGIGNFEVDFFGKLQAMSEAARQRYLAST
CHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHH
YGRDAARGALIAEVLRAYTAERTTAQALQQLQSLDADSAALLAIAERHYQVGLIARDERD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCHHH
AQRRQADQAHVAALQGNDNHAAAVRALQLLVGYDSTPVPGDLQGLIAADTPASAWRALDS
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHH
SLLLQRPDIQQAELELRAANADIGAARAAFFPSITLSSSVGTASDGLNGLFSAGHGLWSF
HHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCCHHHHH
MPQLNLPLFDGGRNRANLELAQVRKRADVVAYEQVIESAFREVANALDAHATLSQAEPRA
HHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
REQVEREQLRLARMHARVDAGLEDRSALLAERTRIAQTELDYLDTARQRVLSRIALFQAF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGVRLPTAS
HHCCCCCCC
>Mature Secondary Structure
MIPQIIPHRWSCVCLVAASAVLAAGCSLTPAYQRPAVSVPATFGSPQAASAPASDRTDAN
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ATTTVALNEQARAFLQRFAPDRDLRPLVERALAHNGDFRRAALQVEQARAHSGIAQASRL
CEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
PALAVGAQQLRQHFDNPALDARYQQDLVIANAGIGNFEVDFFGKLQAMSEAARQRYLAST
CHHHHHHHHHHHHCCCCCCCCHHHCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHH
YGRDAARGALIAEVLRAYTAERTTAQALQQLQSLDADSAALLAIAERHYQVGLIARDERD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCHHH
AQRRQADQAHVAALQGNDNHAAAVRALQLLVGYDSTPVPGDLQGLIAADTPASAWRALDS
HHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHH
SLLLQRPDIQQAELELRAANADIGAARAAFFPSITLSSSVGTASDGLNGLFSAGHGLWSF
HHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCCHHHHH
MPQLNLPLFDGGRNRANLELAQVRKRADVVAYEQVIESAFREVANALDAHATLSQAEPRA
HHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
REQVEREQLRLARMHARVDAGLEDRSALLAERTRIAQTELDYLDTARQRVLSRIALFQAF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGVRLPTAS
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]