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The map label for this gene is maeB [H]

Identifier: 84622672

GI number: 84622672

Start: 1112022

End: 1114331

Strand: Direct

Name: maeB [H]

Synonym: XOO_1015

Alternate gene names: 84622672

Gene position: 1112022-1114331 (Clockwise)

Preceding gene: 84622671

Following gene: 84622673

Centisome position: 22.51

GC content: 65.24

Gene sequence:

>2310_bases
ATGTCCACCGACGACTTCAAACAGGCCGCCCTCGACTATCACCGCCAGCAGCCGGCGGGCAAGATCAAGGTCACCGCGAC
CAAGCCGATGCTGACCCAGCGCGATCTGTCGCTGGCGTATTCGCCGGGCGTGGCCTTCGCCTGCGAGGCCATCGTCGACG
ATGCCACCCAGGCCAGCGAGCTCACCGCGCGCGGCAATCTGGTGGCGGTCATCACCAACGGCACCGCGGTGCTGGGCCTG
GGCAACATCGGTCCGCTGGCCTCCAAGCCGGTGATGGAAGGCAAGGGCGTGCTGTTCCAGAAGTTCGCCGGCATCGACGT
GTTCGATATCGAAATCAGCGAGAACGACCCGGACAAGCTGGTCGATATCATCGCCAGCCTGGAGCCCACCTTCGGCGGCA
TCAATCTGGAAGACATCAAGGCGCCTGAGTGCTTCATCGTCGAGCGCAAGCTGCGCGAGCGCATGAACATCCCGGTGTTC
CATGACGACCAGCACGGCACCGCGATCATCGTCGGCGCTGCCGTGCTCAACGCGCTGGTGGTCACTGGCAAGAAGATCGA
GGAGGTCAAGCTGGCCACCACCGGCATGGGCGCGGCGGGCATTTCCTGCGTCAACATGCTGGTCTCGCTGGGCCTGAAGC
CGGAGAACATCCTGGCGCTGGACCGTGACGGCGTGATCCACACCGGCCGCACCGACCTGGACCCGGACAAGCAGCGCTAT
GCGCGCGACACCGACAAGCGCACCCTGGCCGAGATCGTCGAAGGCGCGGATATCTTCCTGGGCCTGTCGGCGGCCGGCAT
CCTCAAGCCGGAGATGGTCGCCAGCATGGCGCGCCAGCCGGTGATCTTCGCGCTGGCCAATCCCAACCCGGAAATCACCC
CGGAAGCGGCCAAGGCGGTGCGCCCGGATTGCATCATCGGCACCGGCCGTTCGGACTATCCGAACCAGATCAACAACGTG
CTGTGCTTCCCGTATCTGTTCCGTGGCGCGCTGGACGTGGGCGCCACCGGCATCAATGAGGAAATGAAGATCGCCTGCGT
CAAGGCGATCGCCGCGATGGCGCGGCGCGAGGCCTCCGACCTGGGCGCAGCCTACGGCGGCGAGACCCCGAGCTTCGGCC
CGGAATACCTGATTCCGCGTCCGCTCGACCCGCGTCTGCTGGTGGAGTTGTCGTCTGCGGTTGCGCAGGCGGCGATGGAT
TCGGGCGTGGCCACGCGCCCGATCACCGACATGGAGGCCTACCGCGACAAGCTCGGCCAGTTCGTCTACCGCACCAGCCT
GATGATGAAGCCGGTCTACGACCGTGCGCGCGCCGACAAGCAGCGCGTGGTGTATGCCGAAGGCGAAGAAGAAGTGGTGC
TGCGCGCGGTGCAGAACGTGGTCGACGAAGGCCTGGCCTTCCCGATCCTGATCGGCCGCCCTGACGTCATCGAAGCGCGT
ATCGAGCGCATGGGCCTGCGCCTGACCGCCGGCGTGGACTTCGAGATCACCAACATCCTCGACGACCCCCGCTTCAACGA
TTACTGGCAGTACTACCACGCGCTCACCGAGCGCCGCGGCGTGACCGTCACCGCGGCCAAGGAACTGATGCGCTCGCGTC
CAACCCTGATCGCGGCGGTCATGGTGGCGCGCGGCGAAGCCGACGCGATGCTGTCCGGCGTGGTCGGCCGCTTCCACAAG
AAGCTGGGCTATGCGCGCAGCGTGATTCCGCTGGAACCGCGGGTGAGTTCCACCTCGGCGATGACCGGCGTGATCAACCA
GCTCGGCGTGTTCTTCTTCCTGGACACGCACGTGCAGGAAGACCCCACCGTGGAGCAGGTGGTGGAAGCCACGTTGCAGG
CCGCGTATCGCCTCAAGCTGTTCGGCATCGAGCCCAATATCGCGTTGCTGTCGCATTCCAACTTCGGCAGCCACGACTCG
CGCGATGCGCTGAAGATGCGCCAGGTGCGCGAAGCACTGCTCAAGCGCAAGCCCGAGCTCAACATCGACGGCGAAATGCA
GGGCGATACCGCCTGGGACGAAGCGCTGCGCAAGCAGATCATGCCCAACAGCACCTTGAAGGGTCGCGCCAACCTGTTCG
TGCTGCCGAACCTGGAAGCGGCCAACATCGCCTACAACCTGGTGCGCGTGTTCACCGATGGCGTGGCGATCGGCCCGATC
CTGATGGGCATCTCCAAGCCGGTGCATATCCTCACCACCAGCGCCACCTCGCGCCGGGTGATGAACATGACCGCGATTGC
CGCAGTGGATGCACAGATCCGCAAGCTGCTGGAAGCCGAGAAGGGCGGGGCAGACAAGAGCAACGACTGA

Upstream 100 bases:

>100_bases
CATGCGATCTCCCTGCCGCGCTGACAGCTGCGCGACAGGCCCTTGTTCAGGCAGGAGGGTAGAATTCAGTTCTCCTGCGC
CTTCGAGACACACACAGCCG

Downstream 100 bases:

>100_bases
GGGGCTTGGCGGCACGGTAGCGCCGTCGGATGCTGTGCCCTCTCGCTCAGCGGGAGGGCGGCGGATTCATCGGCGCCAGG
TGTTCGGCCGTTTGAGCCTG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MSTDDFKQAALDYHRQQPAGKIKVTATKPMLTQRDLSLAYSPGVAFACEAIVDDATQASELTARGNLVAVITNGTAVLGL
GNIGPLASKPVMEGKGVLFQKFAGIDVFDIEISENDPDKLVDIIASLEPTFGGINLEDIKAPECFIVERKLRERMNIPVF
HDDQHGTAIIVGAAVLNALVVTGKKIEEVKLATTGMGAAGISCVNMLVSLGLKPENILALDRDGVIHTGRTDLDPDKQRY
ARDTDKRTLAEIVEGADIFLGLSAAGILKPEMVASMARQPVIFALANPNPEITPEAAKAVRPDCIIGTGRSDYPNQINNV
LCFPYLFRGALDVGATGINEEMKIACVKAIAAMARREASDLGAAYGGETPSFGPEYLIPRPLDPRLLVELSSAVAQAAMD
SGVATRPITDMEAYRDKLGQFVYRTSLMMKPVYDRARADKQRVVYAEGEEEVVLRAVQNVVDEGLAFPILIGRPDVIEAR
IERMGLRLTAGVDFEITNILDDPRFNDYWQYYHALTERRGVTVTAAKELMRSRPTLIAAVMVARGEADAMLSGVVGRFHK
KLGYARSVIPLEPRVSSTSAMTGVINQLGVFFFLDTHVQEDPTVEQVVEATLQAAYRLKLFGIEPNIALLSHSNFGSHDS
RDALKMRQVREALLKRKPELNIDGEMQGDTAWDEALRKQIMPNSTLKGRANLFVLPNLEAANIAYNLVRVFTDGVAIGPI
LMGISKPVHILTTSATSRRVMNMTAIAAVDAQIRKLLEAEKGGADKSND

Sequences:

>Translated_769_residues
MSTDDFKQAALDYHRQQPAGKIKVTATKPMLTQRDLSLAYSPGVAFACEAIVDDATQASELTARGNLVAVITNGTAVLGL
GNIGPLASKPVMEGKGVLFQKFAGIDVFDIEISENDPDKLVDIIASLEPTFGGINLEDIKAPECFIVERKLRERMNIPVF
HDDQHGTAIIVGAAVLNALVVTGKKIEEVKLATTGMGAAGISCVNMLVSLGLKPENILALDRDGVIHTGRTDLDPDKQRY
ARDTDKRTLAEIVEGADIFLGLSAAGILKPEMVASMARQPVIFALANPNPEITPEAAKAVRPDCIIGTGRSDYPNQINNV
LCFPYLFRGALDVGATGINEEMKIACVKAIAAMARREASDLGAAYGGETPSFGPEYLIPRPLDPRLLVELSSAVAQAAMD
SGVATRPITDMEAYRDKLGQFVYRTSLMMKPVYDRARADKQRVVYAEGEEEVVLRAVQNVVDEGLAFPILIGRPDVIEAR
IERMGLRLTAGVDFEITNILDDPRFNDYWQYYHALTERRGVTVTAAKELMRSRPTLIAAVMVARGEADAMLSGVVGRFHK
KLGYARSVIPLEPRVSSTSAMTGVINQLGVFFFLDTHVQEDPTVEQVVEATLQAAYRLKLFGIEPNIALLSHSNFGSHDS
RDALKMRQVREALLKRKPELNIDGEMQGDTAWDEALRKQIMPNSTLKGRANLFVLPNLEAANIAYNLVRVFTDGVAIGPI
LMGISKPVHILTTSATSRRVMNMTAIAAVDAQIRKLLEAEKGGADKSND
>Mature_768_residues
STDDFKQAALDYHRQQPAGKIKVTATKPMLTQRDLSLAYSPGVAFACEAIVDDATQASELTARGNLVAVITNGTAVLGLG
NIGPLASKPVMEGKGVLFQKFAGIDVFDIEISENDPDKLVDIIASLEPTFGGINLEDIKAPECFIVERKLRERMNIPVFH
DDQHGTAIIVGAAVLNALVVTGKKIEEVKLATTGMGAAGISCVNMLVSLGLKPENILALDRDGVIHTGRTDLDPDKQRYA
RDTDKRTLAEIVEGADIFLGLSAAGILKPEMVASMARQPVIFALANPNPEITPEAAKAVRPDCIIGTGRSDYPNQINNVL
CFPYLFRGALDVGATGINEEMKIACVKAIAAMARREASDLGAAYGGETPSFGPEYLIPRPLDPRLLVELSSAVAQAAMDS
GVATRPITDMEAYRDKLGQFVYRTSLMMKPVYDRARADKQRVVYAEGEEEVVLRAVQNVVDEGLAFPILIGRPDVIEARI
ERMGLRLTAGVDFEITNILDDPRFNDYWQYYHALTERRGVTVTAAKELMRSRPTLIAAVMVARGEADAMLSGVVGRFHKK
LGYARSVIPLEPRVSSTSAMTGVINQLGVFFFLDTHVQEDPTVEQVVEATLQAAYRLKLFGIEPNIALLSHSNFGSHDSR
DALKMRQVREALLKRKPELNIDGEMQGDTAWDEALRKQIMPNSTLKGRANLFVLPNLEAANIAYNLVRVFTDGVAIGPIL
MGISKPVHILTTSATSRRVMNMTAIAAVDAQIRKLLEAEKGGADKSND

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI62420882, Length=411, Percent_Identity=24.5742092457421, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI62420880, Length=411, Percent_Identity=24.5742092457421, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI239049447, Length=411, Percent_Identity=24.5742092457421, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4505143, Length=409, Percent_Identity=23.4718826405868, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788806, Length=757, Percent_Identity=58.9167767503302, Blast_Score=902, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=318, Percent_Identity=29.559748427673, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788800, Length=316, Percent_Identity=29.4303797468354, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI87081919, Length=240, Percent_Identity=25.4166666666667, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537199, Length=345, Percent_Identity=28.4057971014493, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281362674, Length=490, Percent_Identity=26.1224489795918, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281362672, Length=490, Percent_Identity=26.530612244898, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21356279, Length=490, Percent_Identity=26.1224489795918, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78707242, Length=354, Percent_Identity=25.7062146892655, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI78707238, Length=354, Percent_Identity=25.7062146892655, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI78707240, Length=354, Percent_Identity=25.7062146892655, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 83580; Mature: 83449

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDDFKQAALDYHRQQPAGKIKVTATKPMLTQRDLSLAYSPGVAFACEAIVDDATQASE
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHH
LTARGNLVAVITNGTAVLGLGNIGPLASKPVMEGKGVLFQKFAGIDVFDIEISENDPDKL
HEECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCHHHH
VDIIASLEPTFGGINLEDIKAPECFIVERKLRERMNIPVFHDDQHGTAIIVGAAVLNALV
HHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHH
VTGKKIEEVKLATTGMGAAGISCVNMLVSLGLKPENILALDRDGVIHTGRTDLDPDKQRY
HCCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHH
ARDTDKRTLAEIVEGADIFLGLSAAGILKPEMVASMARQPVIFALANPNPEITPEAAKAV
HCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHC
RPDCIIGTGRSDYPNQINNVLCFPYLFRGALDVGATGINEEMKIACVKAIAAMARREASD
CCCEEEECCCCCCCHHHHCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGAAYGGETPSFGPEYLIPRPLDPRLLVELSSAVAQAAMDSGVATRPITDMEAYRDKLGQ
HCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FVYRTSLMMKPVYDRARADKQRVVYAEGEEEVVLRAVQNVVDEGLAFPILIGRPDVIEAR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
IERMGLRLTAGVDFEITNILDDPRFNDYWQYYHALTERRGVTVTAAKELMRSRPTLIAAV
HHHCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
MVARGEADAMLSGVVGRFHKKLGYARSVIPLEPRVSSTSAMTGVINQLGVFFFLDTHVQE
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCC
DPTVEQVVEATLQAAYRLKLFGIEPNIALLSHSNFGSHDSRDALKMRQVREALLKRKPEL
CCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
NIDGEMQGDTAWDEALRKQIMPNSTLKGRANLFVLPNLEAANIAYNLVRVFTDGVAIGPI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHH
LMGISKPVHILTTSATSRRVMNMTAIAAVDAQIRKLLEAEKGGADKSND
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STDDFKQAALDYHRQQPAGKIKVTATKPMLTQRDLSLAYSPGVAFACEAIVDDATQASE
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHH
LTARGNLVAVITNGTAVLGLGNIGPLASKPVMEGKGVLFQKFAGIDVFDIEISENDPDKL
HEECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCHHHH
VDIIASLEPTFGGINLEDIKAPECFIVERKLRERMNIPVFHDDQHGTAIIVGAAVLNALV
HHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHH
VTGKKIEEVKLATTGMGAAGISCVNMLVSLGLKPENILALDRDGVIHTGRTDLDPDKQRY
HCCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCHHHH
ARDTDKRTLAEIVEGADIFLGLSAAGILKPEMVASMARQPVIFALANPNPEITPEAAKAV
HCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHC
RPDCIIGTGRSDYPNQINNVLCFPYLFRGALDVGATGINEEMKIACVKAIAAMARREASD
CCCEEEECCCCCCCHHHHCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGAAYGGETPSFGPEYLIPRPLDPRLLVELSSAVAQAAMDSGVATRPITDMEAYRDKLGQ
HCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FVYRTSLMMKPVYDRARADKQRVVYAEGEEEVVLRAVQNVVDEGLAFPILIGRPDVIEAR
HHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
IERMGLRLTAGVDFEITNILDDPRFNDYWQYYHALTERRGVTVTAAKELMRSRPTLIAAV
HHHCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHH
MVARGEADAMLSGVVGRFHKKLGYARSVIPLEPRVSSTSAMTGVINQLGVFFFLDTHVQE
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCC
DPTVEQVVEATLQAAYRLKLFGIEPNIALLSHSNFGSHDSRDALKMRQVREALLKRKPEL
CCCHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
NIDGEMQGDTAWDEALRKQIMPNSTLKGRANLFVLPNLEAANIAYNLVRVFTDGVAIGPI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHH
LMGISKPVHILTTSATSRRVMNMTAIAAVDAQIRKLLEAEKGGADKSND
HHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]