Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 84488939

GI number: 84488939

Start: 120313

End: 121134

Strand: Direct

Name: dapB

Synonym: Msp_0109

Alternate gene names: 84488939

Gene position: 120313-121134 (Clockwise)

Preceding gene: 84488938

Following gene: 84488940

Centisome position: 6.81

GC content: 33.82

Gene sequence:

>822_bases
ATGATAAGAGTAGCAGTTACAGGTTGTGCAGGAAATATGGGTTCTAAAATCATTAAAACTGTACAAGCACAAGATAATAT
GGAAGTAGTAATGGGAATAGAAATGCCAAATAGTCCTCTAGCAGGTAATGATTTAGGTCAACAAATAGGTTTAGGTCCAA
TGGGTGTGGAAATAATTGGTTCACAAGACTTAAAAACTGAATTAGAAAAAGTTAAACCAGATGTACTTGTTGACTTTACA
ATAGCTAAAGCAGCAGTAGAAACAGTTAAAATTTGTGCTGAATGTGGTGTAAATGTTGTTGTTGGAACAACAGGATTAAA
TGATGAACAATTAGATGTCATGCATAAAGCTATTAAAGATAATGATATTAAAGCAGTTATTTCTCCAAACATGGCCACAG
GAGTGAATGTATTCTTTGAAATTGTAGGACAAGTTGCAAAAATTTTAGGTAATGAATACGATGTTGAAATTGTAGAAGCA
CATCATCATAACAAACAAGATGCACCTTCTGGAACAGCAAAAAGAGCTGCAGAAATAGTAGCAGAAAATCTTAATCTAGA
TCTTAAGGAAAAAGCATGTTATGGCCGTGAAGGTATGGTTGGTAAAAGACCAGAAAATGAAATTGGAATACATGCTGTAC
GTGGTGGAGATATTGTAGGAGATCATACTGTAATGTTCTGTGGTGATGGTGAAAGAATAGAAGTAATTCACAGAGCATCT
ACAAGACAAGCATTTGTAAATGGTGTAATTCGTGCAATTAACTACCAAAGTTCTAAACAAGATAAAAATATTGCAGACAT
GTTTGATGTACTGGGATTATAA

Upstream 100 bases:

>100_bases
TGGACTTAGAATGCCAATAAATGAAATCTGTGATGAAAATGAAGTAATATTAAAAGAGATTCTTAAAGAAAATAACTTAA
TATAAAAAGGAGTGTAATAC

Downstream 100 bases:

>100_bases
TAAGTAGGTGTTTTCATGGTAAGAAATGTATGTGTACTTGGTGCAACTGGAATGGTAGGTCAACGTTTTATCCAGTTATT
ATCTCAAGTACCAGATTTTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIRVAVTGCAGNMGSKIIKTVQAQDNMEVVMGIEMPNSPLAGNDLGQQIGLGPMGVEIIGSQDLKTELEKVKPDVLVDFT
IAKAAVETVKICAECGVNVVVGTTGLNDEQLDVMHKAIKDNDIKAVISPNMATGVNVFFEIVGQVAKILGNEYDVEIVEA
HHHNKQDAPSGTAKRAAEIVAENLNLDLKEKACYGREGMVGKRPENEIGIHAVRGGDIVGDHTVMFCGDGERIEVIHRAS
TRQAFVNGVIRAINYQSSKQDKNIADMFDVLGL

Sequences:

>Translated_273_residues
MIRVAVTGCAGNMGSKIIKTVQAQDNMEVVMGIEMPNSPLAGNDLGQQIGLGPMGVEIIGSQDLKTELEKVKPDVLVDFT
IAKAAVETVKICAECGVNVVVGTTGLNDEQLDVMHKAIKDNDIKAVISPNMATGVNVFFEIVGQVAKILGNEYDVEIVEA
HHHNKQDAPSGTAKRAAEIVAENLNLDLKEKACYGREGMVGKRPENEIGIHAVRGGDIVGDHTVMFCGDGERIEVIHRAS
TRQAFVNGVIRAINYQSSKQDKNIADMFDVLGL
>Mature_273_residues
MIRVAVTGCAGNMGSKIIKTVQAQDNMEVVMGIEMPNSPLAGNDLGQQIGLGPMGVEIIGSQDLKTELEKVKPDVLVDFT
IAKAAVETVKICAECGVNVVVGTTGLNDEQLDVMHKAIKDNDIKAVISPNMATGVNVFFEIVGQVAKILGNEYDVEIVEA
HHHNKQDAPSGTAKRAAEIVAENLNLDLKEKACYGREGMVGKRPENEIGIHAVRGGDIVGDHTVMFCGDGERIEVIHRAS
TRQAFVNGVIRAINYQSSKQDKNIADMFDVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=39.051094890511, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_METST (Q2NHW0)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447171.1
- HSSP:   Q9X1K8
- ProteinModelPortal:   Q2NHW0
- STRING:   Q2NHW0
- GeneID:   3855389
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0109
- NMPDR:   fig|339860.6.peg.107
- eggNOG:   arNOG05038
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- PhylomeDB:   Q2NHW0
- ProtClustDB:   PRK00048
- BioCyc:   MSTA339860:MSP_0109-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29290; Mature: 29290

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAVTGCAGNMGSKIIKTVQAQDNMEVVMGIEMPNSPLAGNDLGQQIGLGPMGVEIIG
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEC
SQDLKTELEKVKPDVLVDFTIAKAAVETVKICAECGVNVVVGTTGLNDEQLDVMHKAIKD
CCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCC
NDIKAVISPNMATGVNVFFEIVGQVAKILGNEYDVEIVEAHHHNKQDAPSGTAKRAAEIV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
AENLNLDLKEKACYGREGMVGKRPENEIGIHAVRGGDIVGDHTVMFCGDGERIEVIHRAS
HHHCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCEECCCEEEEECCCCEEEEEEHHH
TRQAFVNGVIRAINYQSSKQDKNIADMFDVLGL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIRVAVTGCAGNMGSKIIKTVQAQDNMEVVMGIEMPNSPLAGNDLGQQIGLGPMGVEIIG
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEC
SQDLKTELEKVKPDVLVDFTIAKAAVETVKICAECGVNVVVGTTGLNDEQLDVMHKAIKD
CCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCC
NDIKAVISPNMATGVNVFFEIVGQVAKILGNEYDVEIVEAHHHNKQDAPSGTAKRAAEIV
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
AENLNLDLKEKACYGREGMVGKRPENEIGIHAVRGGDIVGDHTVMFCGDGERIEVIHRAS
HHHCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCEECCCEEEEECCCCEEEEEEHHH
TRQAFVNGVIRAINYQSSKQDKNIADMFDVLGL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA