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The map label for this gene is asd

Identifier: 84488940

GI number: 84488940

Start: 121150

End: 122199

Strand: Direct

Name: asd

Synonym: Msp_0110

Alternate gene names: 84488940

Gene position: 121150-122199 (Clockwise)

Preceding gene: 84488939

Following gene: 84488941

Centisome position: 6.85

GC content: 34.57

Gene sequence:

>1050_bases
ATGGTAAGAAATGTATGTGTACTTGGTGCAACTGGAATGGTAGGTCAACGTTTTATCCAGTTATTATCTCAAGTACCAGA
TTTTAATATAGTGAATGTAGCAGCTTCTGAGAAATCTGCTGGTAAAAGATATGAAGATGCTGTTACTTGGCATCAAACAA
CTCCTATTCCTGAAGAAGTAAGGGATATGAGAATTGTTAATACGAATCCTGATGAGATTAGTGATGATGTAGACTTTGTA
TTTGCTTCTCTTCCTGCTCAGCTTGCAGAACCTGTAGAAGCAGCATTTGCAGAGAAATATATTGTTGCATCCAATGCTAG
TGTAAATCGTATGAAAGAAAATATTCCACTAGTAATTCCGGAAGTTAATCCTGAACATCTTGAAATGATGGAGCTACAAA
AGGATATTAATGGATGGGATGGATGTATTGTAACAAATCCAAATTGTTCAACCATAGCATTAACTTTAACTTTAAAACCA
TTATTTGATAAATATACATTTAAAAGAGTTTCTGTAACTACTATGCAAGCTGTTAGTGGTGCTGGATACAATGGTGTTCC
ATCAATGGGTATTGTGGATAATTTAATACCTTATATTGGCGGAGAAGAAGAAAAAATGCAATCTGAAACATTACATTTAC
TTGGAAAAGTCAATGGTGGGCTTGTAGATAGGGCAAATTTCCCATTAAGTGCTTCATGTAATAGGGTGGCTGTTGTTGAT
GGTCATACTGAATCAGTTTCAATAGAATTTGAGGAAGATATTACAGTAGATGATATTGAAAAAACATTATCTGAATTTAG
AGGATTACCTCAAGAAAGAAATCTATCTTTTGCACCTAAACAACCTGTTATTGTGAGAAAAGAGGAAGATAGACCTCAAC
CTCGTATGGATAGAGATGCAGGTCATGGTATGAGTGTATCTGTTGGTAGAGTAAGAGAAGATGTATTTGATAATAGTTTC
AAATATACTCTTGTTGGTCATAACACTATTCGTGGTGCTGCTGGAGCATCAATACTTAATGCTCAATTGATTTCTGAGTT
ATATTTATAG

Upstream 100 bases:

>100_bases
AAATGGTGTAATTCGTGCAATTAACTACCAAAGTTCTAAACAAGATAAAAATATTGCAGACATGTTTGATGTACTGGGAT
TATAATAAGTAGGTGTTTTC

Downstream 100 bases:

>100_bases
ATGAGTTTTCACTTTTTTTTCTTTTTTTGTGGTGTTGTCATGTCTTTATATTCTTTGGATTTGATGATTTTATATTTTTT
TAATCATTTAATACACACAC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVRNVCVLGATGMVGQRFIQLLSQVPDFNIVNVAASEKSAGKRYEDAVTWHQTTPIPEEVRDMRIVNTNPDEISDDVDFV
FASLPAQLAEPVEAAFAEKYIVASNASVNRMKENIPLVIPEVNPEHLEMMELQKDINGWDGCIVTNPNCSTIALTLTLKP
LFDKYTFKRVSVTTMQAVSGAGYNGVPSMGIVDNLIPYIGGEEEKMQSETLHLLGKVNGGLVDRANFPLSASCNRVAVVD
GHTESVSIEFEEDITVDDIEKTLSEFRGLPQERNLSFAPKQPVIVRKEEDRPQPRMDRDAGHGMSVSVGRVREDVFDNSF
KYTLVGHNTIRGAAGASILNAQLISELYL

Sequences:

>Translated_349_residues
MVRNVCVLGATGMVGQRFIQLLSQVPDFNIVNVAASEKSAGKRYEDAVTWHQTTPIPEEVRDMRIVNTNPDEISDDVDFV
FASLPAQLAEPVEAAFAEKYIVASNASVNRMKENIPLVIPEVNPEHLEMMELQKDINGWDGCIVTNPNCSTIALTLTLKP
LFDKYTFKRVSVTTMQAVSGAGYNGVPSMGIVDNLIPYIGGEEEKMQSETLHLLGKVNGGLVDRANFPLSASCNRVAVVD
GHTESVSIEFEEDITVDDIEKTLSEFRGLPQERNLSFAPKQPVIVRKEEDRPQPRMDRDAGHGMSVSVGRVREDVFDNSF
KYTLVGHNTIRGAAGASILNAQLISELYL
>Mature_349_residues
MVRNVCVLGATGMVGQRFIQLLSQVPDFNIVNVAASEKSAGKRYEDAVTWHQTTPIPEEVRDMRIVNTNPDEISDDVDFV
FASLPAQLAEPVEAAFAEKYIVASNASVNRMKENIPLVIPEVNPEHLEMMELQKDINGWDGCIVTNPNCSTIALTLTLKP
LFDKYTFKRVSVTTMQAVSGAGYNGVPSMGIVDNLIPYIGGEEEKMQSETLHLLGKVNGGLVDRANFPLSASCNRVAVVD
GHTESVSIEFEEDITVDDIEKTLSEFRGLPQERNLSFAPKQPVIVRKEEDRPQPRMDRDAGHGMSVSVGRVREDVFDNSF
KYTLVGHNTIRGAAGASILNAQLISELYL

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=353, Percent_Identity=43.0594900849858, Blast_Score=262, Evalue=7e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38440; Mature: 38440

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNVCVLGATGMVGQRFIQLLSQVPDFNIVNVAASEKSAGKRYEDAVTWHQTTPIPEEV
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHEEECCCCCCCHHH
RDMRIVNTNPDEISDDVDFVFASLPAQLAEPVEAAFAEKYIVASNASVNRMKENIPLVIP
HCEEEECCCHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCCHHHHHHCCCCEEEE
EVNPEHLEMMELQKDINGWDGCIVTNPNCSTIALTLTLKPLFDKYTFKRVSVTTMQAVSG
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECHHHHHHHHHEEEHHHHHHHCC
AGYNGVPSMGIVDNLIPYIGGEEEKMQSETLHLLGKVNGGLVDRANFPLSASCNRVAVVD
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEE
GHTESVSIEFEEDITVDDIEKTLSEFRGLPQERNLSFAPKQPVIVRKEEDRPQPRMDRDA
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
GHGMSVSVGRVREDVFDNSFKYTLVGHNTIRGAAGASILNAQLISELYL
CCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRNVCVLGATGMVGQRFIQLLSQVPDFNIVNVAASEKSAGKRYEDAVTWHQTTPIPEEV
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHEEECCCCCCCHHH
RDMRIVNTNPDEISDDVDFVFASLPAQLAEPVEAAFAEKYIVASNASVNRMKENIPLVIP
HCEEEECCCHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCCHHHHHHCCCCEEEE
EVNPEHLEMMELQKDINGWDGCIVTNPNCSTIALTLTLKPLFDKYTFKRVSVTTMQAVSG
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEECHHHHHHHHHEEEHHHHHHHCC
AGYNGVPSMGIVDNLIPYIGGEEEKMQSETLHLLGKVNGGLVDRANFPLSASCNRVAVVD
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEE
GHTESVSIEFEEDITVDDIEKTLSEFRGLPQERNLSFAPKQPVIVRKEEDRPQPRMDRDA
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
GHGMSVSVGRVREDVFDNSFKYTLVGHNTIRGAAGASILNAQLISELYL
CCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]