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The map label for this gene is cbiL

Identifier: 84488868

GI number: 84488868

Start: 41543

End: 42238

Strand: Direct

Name: cbiL

Synonym: Msp_0038

Alternate gene names: 84488868

Gene position: 41543-42238 (Clockwise)

Preceding gene: 84488866

Following gene: 84488871

Centisome position: 2.35

GC content: 29.31

Gene sequence:

>696_bases
ATGGAAATTGGAAAATTATATGGTTTAGGGGTAGGACCAGGAGACCCTGAACTTGTAACATTAAAAGCAGCAAGAATTAT
TAAAGAAACAGATATTATATTTGCTCCACAATCACGTAATGGTAAACCAAGTGTAGCATTAAATATAGTTCAAAATATAA
TTGATGAAAGAGAAGAAGAATGTGAAATATTACAACCATTATTCCCTATGACTGAAGATAAAGATGAATTAGCAAAATCA
TGGGATGATGCTGCAGAAATGTTATTTGAAAAACTGTCTAATGGTTTAAATGCAGTATTTGTGACTTTAGGTGATCCTAC
AGTATTTAGTACATTTTCTTATGTTTCTAAAAGATTACAAAAAAAGGGTGTTGAAGTAGAATTAGTTCCAGGTATAACAT
CATTCACTGCATGTTCCACAACAGCAGGAATTCAATTAACAGAACAAGATGATATTATGGTAGTAGTACCACAAGTAGAT
GAAAGATTACCTAAATTATTACCATATGTTGATACGTTAGTTGCAATGAAAACTTCAAGACATTTAGATGTATTAGAAGA
TTGTATAAATAAAGATCCAAGAGAAAAAGAAATAGTATCTGTTCAAAACTGTACAATGGAAGATGAAAATGTTGTACACG
GATTTGTAGATAATAAAAAGTATTTTTCAACTAGTATAATTAAGTTTAAAAAATAA

Upstream 100 bases:

>100_bases
TATAAAATGAATATAATCTTTAAATAAAGTTTACTTTAGTTTTTTTAAGTAAATTAAGGTTTTATTATTTTTTATTAAAC
AGATAAGGATAGAAAATATT

Downstream 100 bases:

>100_bases
TCTTCTTTTTTTTAAAACTTTTTAACTAGTTTATCACATAAATCATTCCAATTGAAGTTATCATATACTATTTTTTGAAT
CTCAGAGGGATTTCTTTTAA

Product: CbiL

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEIGKLYGLGVGPGDPELVTLKAARIIKETDIIFAPQSRNGKPSVALNIVQNIIDEREEECEILQPLFPMTEDKDELAKS
WDDAAEMLFEKLSNGLNAVFVTLGDPTVFSTFSYVSKRLQKKGVEVELVPGITSFTACSTTAGIQLTEQDDIMVVVPQVD
ERLPKLLPYVDTLVAMKTSRHLDVLEDCINKDPREKEIVSVQNCTMEDENVVHGFVDNKKYFSTSIIKFKK

Sequences:

>Translated_231_residues
MEIGKLYGLGVGPGDPELVTLKAARIIKETDIIFAPQSRNGKPSVALNIVQNIIDEREEECEILQPLFPMTEDKDELAKS
WDDAAEMLFEKLSNGLNAVFVTLGDPTVFSTFSYVSKRLQKKGVEVELVPGITSFTACSTTAGIQLTEQDDIMVVVPQVD
ERLPKLLPYVDTLVAMKTSRHLDVLEDCINKDPREKEIVSVQNCTMEDENVVHGFVDNKKYFSTSIIKFKK
>Mature_231_residues
MEIGKLYGLGVGPGDPELVTLKAARIIKETDIIFAPQSRNGKPSVALNIVQNIIDEREEECEILQPLFPMTEDKDELAKS
WDDAAEMLFEKLSNGLNAVFVTLGDPTVFSTFSYVSKRLQKKGVEVELVPGITSFTACSTTAGIQLTEQDDIMVVVPQVD
ERLPKLLPYVDTLVAMKTSRHLDVLEDCINKDPREKEIVSVQNCTMEDENVVHGFVDNKKYFSTSIIKFKK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25799; Mature: 25799

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGKLYGLGVGPGDPELVTLKAARIIKETDIIFAPQSRNGKPSVALNIVQNIIDEREEE
CCCCCEEECCCCCCCCCEEEEHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCHHH
CEILQPLFPMTEDKDELAKSWDDAAEMLFEKLSNGLNAVFVTLGDPTVFSTFSYVSKRLQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHH
KKGVEVELVPGITSFTACSTTAGIQLTEQDDIMVVVPQVDERLPKLLPYVDTLVAMKTSR
HCCCEEEEECCCCHHHHHCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
HLDVLEDCINKDPREKEIVSVQNCTMEDENVVHGFVDNKKYFSTSIIKFKK
CHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHEEEECC
>Mature Secondary Structure
MEIGKLYGLGVGPGDPELVTLKAARIIKETDIIFAPQSRNGKPSVALNIVQNIIDEREEE
CCCCCEEECCCCCCCCCEEEEHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCHHH
CEILQPLFPMTEDKDELAKSWDDAAEMLFEKLSNGLNAVFVTLGDPTVFSTFSYVSKRLQ
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHH
KKGVEVELVPGITSFTACSTTAGIQLTEQDDIMVVVPQVDERLPKLLPYVDTLVAMKTSR
HCCCEEEEECCCCHHHHHCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
HLDVLEDCINKDPREKEIVSVQNCTMEDENVVHGFVDNKKYFSTSIIKFKK
CHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]