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The map label for this gene is moeB [H]

Identifier: 83720647

GI number: 83720647

Start: 460925

End: 461749

Strand: Reverse

Name: moeB [H]

Synonym: BTH_I0414

Alternate gene names: 83720647

Gene position: 461749-460925 (Counterclockwise)

Preceding gene: 83720556

Following gene: 83720710

Centisome position: 12.12

GC content: 66.67

Gene sequence:

>825_bases
ATGGCCCGTTTTCTTTGCGCGCCTAGAATAATATTCGAGACTGTTTTACCGCCTTGCGGCCCCACGATGAACGACGAACA
ACTCCTCCGCTATTCCCGCCACATCCTCGTCGACGAAATCGGCATCGAGGCGCAGCAGCGCTTTCTCGACGCGCATGCGA
TCATCGTCGGCGCGGGCGGGCTCGGGTCGCCGGCGGCGATGTATCTCGCGGCGGCGGGCGTCGGCACGATCACGCTCGCC
GACGCCGACACCGTCGATCTCACGAACCTGCAGCGGCAAATCCTGCACGTGAGCGCATCGGTCGGCCGCAAGAAGGTCGA
GTCGGGGCGCGACGCGCTCGCGCAGCTCAATCCCGACGTGAAGGTGAATGCGCTCGCCGAGCGCGTCGACGATGCGTGGC
TGAATGCGCACGTGCCGCACGCAAGCGTCGTGCTCGACTGCACCGACAACTTCGCGACGCGCCACGCGATCAACCGCGCG
TGTGTCGCGCATCGGGTGCCGCTCGTGTCAGGCGCGGCGCTGCGCTTCGACGGGCAGATCAGCACGTTCGACTTCCGCGA
CCCCGGCTCGCCATGCTACGCGTGCGTGTTCCCGGAAGATCAGCCGTTCGAGGAAGTCGCGTGCTCGACGATGGGCGTGT
TCGCGCCGACCGTCGGCATCATCGGCGCAATGCAGGCGGCCGAGGCGCTGCGGGTGATCGGCGGCATTGGCACGACGCTC
GTCGGCCGGCTGATGATGCTGGATTCGCTGCGGATGGAGTGGAGCACGATGAAAATCGCGCGGCAGCCGGATTGCCCGGT
GTGCGGCTCGGGCGGCACGCATTGA

Upstream 100 bases:

>100_bases
CGCGGCTGCGAAGCCTGCGTCGGCTGCGAAGCCCGCGTCGGCGCCGCAACCGCAGTAAGCGCACGGCGCCACGCACGGGC
CATCGCGGCACGCCGCCGCG

Downstream 100 bases:

>100_bases
GCGGCGCGGCTCGCGGCCGCGTGTAATCGTCTGCGTTGACGGCGCCGTTAGCGCAAAAATCTGGCGCGCGATCGCGCGTG
CCCCATACCCGGCTCCTGCC

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MARFLCAPRIIFETVLPPCGPTMNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIIVGAGGLGSPAAMYLAAAGVGTITLA
DADTVDLTNLQRQILHVSASVGRKKVESGRDALAQLNPDVKVNALAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRA
CVAHRVPLVSGAALRFDGQISTFDFRDPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGTTL
VGRLMMLDSLRMEWSTMKIARQPDCPVCGSGGTH

Sequences:

>Translated_274_residues
MARFLCAPRIIFETVLPPCGPTMNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIIVGAGGLGSPAAMYLAAAGVGTITLA
DADTVDLTNLQRQILHVSASVGRKKVESGRDALAQLNPDVKVNALAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRA
CVAHRVPLVSGAALRFDGQISTFDFRDPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGTTL
VGRLMMLDSLRMEWSTMKIARQPDCPVCGSGGTH
>Mature_273_residues
ARFLCAPRIIFETVLPPCGPTMNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIIVGAGGLGSPAAMYLAAAGVGTITLAD
ADTVDLTNLQRQILHVSASVGRKKVESGRDALAQLNPDVKVNALAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRAC
VAHRVPLVSGAALRFDGQISTFDFRDPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGTTLV
GRLMMLDSLRMEWSTMKIARQPDCPVCGSGGTH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=267, Percent_Identity=40.8239700374532, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI4885649, Length=143, Percent_Identity=31.4685314685315, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1787048, Length=251, Percent_Identity=45.0199203187251, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87082356, Length=252, Percent_Identity=45.2380952380952, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1789177, Length=150, Percent_Identity=37.3333333333333, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=262, Percent_Identity=39.6946564885496, Blast_Score=199, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193203301, Length=165, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86565433, Length=144, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86565431, Length=144, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=254, Percent_Identity=36.2204724409449, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322639, Length=160, Percent_Identity=28.125, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320598, Length=166, Percent_Identity=26.5060240963855, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582879, Length=250, Percent_Identity=40, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24660640, Length=159, Percent_Identity=32.0754716981132, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573937, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29265; Mature: 29134

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFLCAPRIIFETVLPPCGPTMNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIIVGAGG
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCC
LGSPAAMYLAAAGVGTITLADADTVDLTNLQRQILHVSASVGRKKVESGRDALAQLNPDV
CCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KVNALAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQI
CHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCE
STFDFRDPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGTTL
EEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
VGRLMMLDSLRMEWSTMKIARQPDCPVCGSGGTH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARFLCAPRIIFETVLPPCGPTMNDEQLLRYSRHILVDEIGIEAQQRFLDAHAIIVGAGG
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCC
LGSPAAMYLAAAGVGTITLADADTVDLTNLQRQILHVSASVGRKKVESGRDALAQLNPDV
CCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KVNALAERVDDAWLNAHVPHASVVLDCTDNFATRHAINRACVAHRVPLVSGAALRFDGQI
CHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCE
STFDFRDPGSPCYACVFPEDQPFEEVACSTMGVFAPTVGIIGAMQAAEALRVIGGIGTTL
EEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
VGRLMMLDSLRMEWSTMKIARQPDCPVCGSGGTH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]