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The map label for this gene is xerD [H]

Identifier: 83720485

GI number: 83720485

Start: 835182

End: 836183

Strand: Direct

Name: xerD [H]

Synonym: BTH_I0726

Alternate gene names: 83720485

Gene position: 835182-836183 (Clockwise)

Preceding gene: 83721435

Following gene: 83720025

Centisome position: 21.93

GC content: 70.76

Gene sequence:

>1002_bases
ATGGCGCGCGCAGCACGCATTCCCGCGCCCGGCCCGGCGAGCGGCGGCGCCGGCCGGGGGGCCGCGCCGTCGGCCGATCG
CCCGGCCGACGAGTTGGCCGCGTCGCCGGCGTGGCGCGACAGCCGCACGTCGATCGATCTGTTCTGCGACGCGATGTGGC
TCGAGCACGGGCTGTCACGCAACACGCTCGACGCGTACCGGCGCGACCTGCAATTGTTCGCGCAGTGGCTCGCCGCGCGG
CACGCGGTAAGTCTCGATCGCACCGAAAGGCCGATGCTCGAGGGCTACATCGCCGCGCGCAGCGATGGCAAGGCGACGTC
GTCGAATCGCCGGCTGTCGGTGTTTCGCCGCTATTACGGCTGGGCGGTGCGCGAGCACCGCGCGGCCGTCGATCCGACGC
TCAGGATCGCGTCCGCGAAGCAGGCGCCGCGGTTTCCGTCGACGTTGTCCGAGGCCCAGGTCGAGGCGCTTCTCGCCGCG
CCCGACGTCGACACGCCGCTCGGCTTGCGCGACCGCACGATGCTCGAGCTGATGTATGCGAGCGGGCTGCGCGTGAGCGA
ACTCGTCACGCTGAAGACGGTCGAGGTCGGATTGAACGAAGGCGTGGTGCGCGTGACGGGCAAAGGCTCGAAGGAGCGGC
TCGTGCCGTTCGGCGAAGTCGCGCACGGCTGGATCGAACGCTATCTGCGCGACGCGCGGCCCGCGCTGCTCGGCGCGCGC
GCGGCGGACGCGCTGTTCGTCACCGCGCGCGGCGACGGCATGACGCGCCAGCAGTTCTGGAACATCATCAAGCGCCATGC
GCAGCAGGCGGACGTTCGCGCGCATCTGTCGCCGCACACGCTGCGGCACGCGTTCGCGACGCACTTGCTGAATCACGGCG
CGGACCTGCGGGTCGTGCAACTGCTGCTCGGCCATAGCGACATCTCGACGACGCAGATCTACACGCACGTCGCGCGCGAG
CGGTTGAAGGCGCTGCATGCGACGCATCATCCGCGCGGGTGA

Upstream 100 bases:

>100_bases
TCGCGTCCGGCGGGATCGGCGGCTTCGCGAACCACGACGACGAAGGCTATTTCCTGAAGGTCAAGCGCTGGTTGCTCGCG
CATGAGGGCGTGCGGTTCTG

Downstream 100 bases:

>100_bases
CGCTTGCCCGTTGCGATCGGGGCGCCGTCGCGCGTGCGCGATCGTCGGGATCGCGCGCCGGCACACGATGTGTGCCCGCG
CCCCAGGTCTTGTTCGGGCC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MARAARIPAPGPASGGAGRGAAPSADRPADELAASPAWRDSRTSIDLFCDAMWLEHGLSRNTLDAYRRDLQLFAQWLAAR
HAVSLDRTERPMLEGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRAAVDPTLRIASAKQAPRFPSTLSEAQVEALLAA
PDVDTPLGLRDRTMLELMYASGLRVSELVTLKTVEVGLNEGVVRVTGKGSKERLVPFGEVAHGWIERYLRDARPALLGAR
AADALFVTARGDGMTRQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARE
RLKALHATHHPRG

Sequences:

>Translated_333_residues
MARAARIPAPGPASGGAGRGAAPSADRPADELAASPAWRDSRTSIDLFCDAMWLEHGLSRNTLDAYRRDLQLFAQWLAAR
HAVSLDRTERPMLEGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRAAVDPTLRIASAKQAPRFPSTLSEAQVEALLAA
PDVDTPLGLRDRTMLELMYASGLRVSELVTLKTVEVGLNEGVVRVTGKGSKERLVPFGEVAHGWIERYLRDARPALLGAR
AADALFVTARGDGMTRQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARE
RLKALHATHHPRG
>Mature_332_residues
ARAARIPAPGPASGGAGRGAAPSADRPADELAASPAWRDSRTSIDLFCDAMWLEHGLSRNTLDAYRRDLQLFAQWLAARH
AVSLDRTERPMLEGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRAAVDPTLRIASAKQAPRFPSTLSEAQVEALLAAP
DVDTPLGLRDRTMLELMYASGLRVSELVTLKTVEVGLNEGVVRVTGKGSKERLVPFGEVAHGWIERYLRDARPALLGARA
ADALFVTARGDGMTRQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARER
LKALHATHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=56.1643835616438, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=38.3333333333333, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790767, Length=173, Percent_Identity=27.1676300578035, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36750; Mature: 36619

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAARIPAPGPASGGAGRGAAPSADRPADELAASPAWRDSRTSIDLFCDAMWLEHGLSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
NTLDAYRRDLQLFAQWLAARHAVSLDRTERPMLEGYIAARSDGKATSSNRRLSVFRRYYG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WAVREHRAAVDPTLRIASAKQAPRFPSTLSEAQVEALLAAPDVDTPLGLRDRTMLELMYA
HHHHHHHHHCCCHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
SGLRVSELVTLKTVEVGLNEGVVRVTGKGSKERLVPFGEVAHGWIERYLRDARPALLGAR
CCCCHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
AADALFVTARGDGMTRQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
LLLGHSDISTTQIYTHVARERLKALHATHHPRG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARAARIPAPGPASGGAGRGAAPSADRPADELAASPAWRDSRTSIDLFCDAMWLEHGLSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
NTLDAYRRDLQLFAQWLAARHAVSLDRTERPMLEGYIAARSDGKATSSNRRLSVFRRYYG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WAVREHRAAVDPTLRIASAKQAPRFPSTLSEAQVEALLAAPDVDTPLGLRDRTMLELMYA
HHHHHHHHHCCCHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
SGLRVSELVTLKTVEVGLNEGVVRVTGKGSKERLVPFGEVAHGWIERYLRDARPALLGAR
CCCCHHHHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
AADALFVTARGDGMTRQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
LLLGHSDISTTQIYTHVARERLKALHATHHPRG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]