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The map label for this gene is mhpR [H]

Identifier: 83720436

GI number: 83720436

Start: 3292820

End: 3293740

Strand: Direct

Name: mhpR [H]

Synonym: BTH_I2865

Alternate gene names: 83720436

Gene position: 3292820-3293740 (Clockwise)

Preceding gene: 83719050

Following gene: 83719275

Centisome position: 86.44

GC content: 65.47

Gene sequence:

>921_bases
GTGAAAGAAAGTGGCAAAACGCGCACACTTTTCCGCATTCGTCTTACAATTGATAAAAATCTGAAATCAAGTTTCGAAAA
AAGAGAGATTTCCGTGACGACACGCACCAATGCCCAAGCCGTCTCCCGAGAACGGGAAGCGACCACCGATGAAATCACGG
CCCTCGCGCGCGGTTTGGCCGTCCTGCGCCGCATCGCGACCTCCGATGCGCCAGTCAGCAACCGGGAACTGGCGGAATTG
ACAGGTATCCCAAAGCCAACTGTCTCGCGCATCACGGCGACGCTCGTCAGCGCAGGCTTCCTGTTCCAGTTGCCCGACAG
CGAGCGCTTCGTGCTGACGGCGTCGGTGCTCGAACTCAGCAACGGCTTCCTGCGCAACTTCGATATCCGCGCACGCTCGC
GGCCATTCCTCGTCGAACTGGCCGAAAAGACGTCGCTGTCCGTCCATCTCGCGGTGCGCGACCGCCTCGACATGGTCGCG
ATCGACGTGATCCGCCCCCGCTCGGCCGTGCTCGTCACGCGGCTCGAAACGGGCTCGCGGATGGACATCGCGCGCACGGC
GGTCGGCCGTGCGTACCTCGCCGCGCTCGAGGACGACGCGCGCCGCGAGCTGATCGGCGCACTGCAGGCCGCGGCGGGCG
ACGACTGGCCGTTCGTCGTATCGCGGCTGAATGCCGCGCTCGCCGACATCGCGCAACACGGCTACGCGATCGCGATCGGC
GAATGGCGCGAAGAACTGAATGCGATCGCGGCGGGCTTCGTCGCGCCGACGGGCCAATGCTACGCGGTCAATTGCGGCGG
CTCCGCGCACCAGTGCACGCCCGACTTCCTGCGCTCGGTCGCGGTGCCCGCGCTGCGCGAGTGCATCGCAAAGATCACGC
GCGAGATCGGCGCCGCCGCGTGGCCGAATCGCGCCCGGTGA

Upstream 100 bases:

>100_bases
CAAGTCAAGCGAAAAATACATGTCCCCACATCATTTCCGGCGCTGCGCGATCCGACATCTCCCTAATAAACTCGGGGTAA
GCCAGTAAATATTGCGCATT

Downstream 100 bases:

>100_bases
AATAGCGCAGCGCGCCGGCCCGCGCCGTTCGGCGTGCCGGCCCGCTGGCGGCGCTCGCCCTTCGCCCGGAGCCCCTCACC
GCAACCCACGCCGCCACACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKESGKTRTLFRIRLTIDKNLKSSFEKREISVTTRTNAQAVSREREATTDEITALARGLAVLRRIATSDAPVSNRELAEL
TGIPKPTVSRITATLVSAGFLFQLPDSERFVLTASVLELSNGFLRNFDIRARSRPFLVELAEKTSLSVHLAVRDRLDMVA
IDVIRPRSAVLVTRLETGSRMDIARTAVGRAYLAALEDDARRELIGALQAAAGDDWPFVVSRLNAALADIAQHGYAIAIG
EWREELNAIAAGFVAPTGQCYAVNCGGSAHQCTPDFLRSVAVPALRECIAKITREIGAAAWPNRAR

Sequences:

>Translated_306_residues
MKESGKTRTLFRIRLTIDKNLKSSFEKREISVTTRTNAQAVSREREATTDEITALARGLAVLRRIATSDAPVSNRELAEL
TGIPKPTVSRITATLVSAGFLFQLPDSERFVLTASVLELSNGFLRNFDIRARSRPFLVELAEKTSLSVHLAVRDRLDMVA
IDVIRPRSAVLVTRLETGSRMDIARTAVGRAYLAALEDDARRELIGALQAAAGDDWPFVVSRLNAALADIAQHGYAIAIG
EWREELNAIAAGFVAPTGQCYAVNCGGSAHQCTPDFLRSVAVPALRECIAKITREIGAAAWPNRAR
>Mature_306_residues
MKESGKTRTLFRIRLTIDKNLKSSFEKREISVTTRTNAQAVSREREATTDEITALARGLAVLRRIATSDAPVSNRELAEL
TGIPKPTVSRITATLVSAGFLFQLPDSERFVLTASVLELSNGFLRNFDIRARSRPFLVELAEKTSLSVHLAVRDRLDMVA
IDVIRPRSAVLVTRLETGSRMDIARTAVGRAYLAALEDDARRELIGALQAAAGDDWPFVVSRLNAALADIAQHGYAIAIG
EWREELNAIAAGFVAPTGQCYAVNCGGSAHQCTPDFLRSVAVPALRECIAKITREIGAAAWPNRAR

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=254, Percent_Identity=27.5590551181102, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082359, Length=159, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786468, Length=215, Percent_Identity=25.1162790697674, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788581, Length=253, Percent_Identity=26.4822134387352, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 33399; Mature: 33399

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESGKTRTLFRIRLTIDKNLKSSFEKREISVTTRTNAQAVSREREATTDEITALARGLA
CCCCCCCEEEEEEEEEECCCHHHHHHHHEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHH
VLRRIATSDAPVSNRELAELTGIPKPTVSRITATLVSAGFLFQLPDSERFVLTASVLELS
HHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEECCCCCCEEEEHHHHHHC
NGFLRNFDIRARSRPFLVELAEKTSLSVHLAVRDRLDMVAIDVIRPRSAVLVTRLETGSR
CCHHCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCC
MDIARTAVGRAYLAALEDDARRELIGALQAAAGDDWPFVVSRLNAALADIAQHGYAIAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEH
EWREELNAIAAGFVAPTGQCYAVNCGGSAHQCTPDFLRSVAVPALRECIAKITREIGAAA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
WPNRAR
CCCCCC
>Mature Secondary Structure
MKESGKTRTLFRIRLTIDKNLKSSFEKREISVTTRTNAQAVSREREATTDEITALARGLA
CCCCCCCEEEEEEEEEECCCHHHHHHHHEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHH
VLRRIATSDAPVSNRELAELTGIPKPTVSRITATLVSAGFLFQLPDSERFVLTASVLELS
HHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEECCCCCCEEEEHHHHHHC
NGFLRNFDIRARSRPFLVELAEKTSLSVHLAVRDRLDMVAIDVIRPRSAVLVTRLETGSR
CCHHCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCC
MDIARTAVGRAYLAALEDDARRELIGALQAAAGDDWPFVVSRLNAALADIAQHGYAIAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEH
EWREELNAIAAGFVAPTGQCYAVNCGGSAHQCTPDFLRSVAVPALRECIAKITREIGAAA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
WPNRAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]