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The map label for this gene is mdtA [H]

Identifier: 83719275

GI number: 83719275

Start: 3293774

End: 3295504

Strand: Direct

Name: mdtA [H]

Synonym: BTH_I2866

Alternate gene names: 83719275

Gene position: 3293774-3295504 (Clockwise)

Preceding gene: 83720436

Following gene: 83721292

Centisome position: 86.47

GC content: 69.44

Gene sequence:

>1731_bases
GTGCCGGCCCGCTGGCGGCGCTCGCCCTTCGCCCGGAGCCCCTCACCGCAACCCACGCCGCCACACACGCTCGCGCGTCG
AAACAGCCGCCAAAGCGAACGCGATCCGGCAAGCCGCGCATCGGCCGAGCGATCCCGTCGCCCGCCCCGCGTCATCGCCG
CATGCCATCGTCCGTTCACCTGTAACGATCGTAATTCGCGGAAAGATAGGGCGCTGGACTGTAACCGTCATGGGGACGTA
GCATCATGCAACCCTGCGCCGCAACCGGCGCGCCCCGCTCTTTGCGTCGCGACCGGGCCGCAGCCGGCCCGCACCGCGCC
GGCCGCGAACGCGGCCCGTGCGCGCCCGTCGCATGCGCTGCACGCCGACTTCCAGATCGAACCGATGGACAATCAAGAAA
AGCCCACGCCCCGCTCTCCCGCCCAACCGCCGTCCGGCTCCGGCCCGCGCCGCCCCCGCCGCAAGCTGATCGCGTTCGGC
GTGCTCGCGGCCGTCGCGATCGGCGGCGTGCTGTGGTGGCATCCGTGGAAGAGCGGCGGCAACCCAAGCACCGAGAGCCG
GCCAGACGGCGCACGCAAGCGCGGCGGCCCCGCCGCGCTCGCGAACCTGCCGCAGCCCGTTCAGGTCGCGACGGCGGCGC
GCGGCGAGATGCCCGTCGTCCTGAACGCGCTCGGCACCGTCACGCCGCTCGCGAACGTGACCGTCAGGACCCAGTTGTCA
GGCTATCTGCAATCGGTGTCGTTCCAGGAAGGCCAGATCGTGAAGCAAGGCGACGTGCTCGCGCAAATCGATCCGCGCCC
GTACCAGATCTCGCTCGCGAACGCACAGGGCGCGCTCGCGCGCGACGAGGCGCTCCTCGCGACCGCGCGCCTCGACCTGA
AGCGCTATCAAACGCTCCTCGCTCAGGACTCGATCGCGAAGCAGACGGCCGACACGCAGGCATCGCTCGTCAAGCAGTAC
GAAGGCACCGTGCAGATCGACCGCGCGGCGGTCGATTCCGCGAAGCTCAATCTCGCCTACGCGCGGATCACCGCGCCCGT
GTCGGGCCGCGTCGGCCTGCGGCAGGTCGATCCGGGCAACTACGTGACGCCGTCGGATGCGAACGGCATCGTCGTCATCA
CGCAATTGCAGCCGATGAGCGTGATCTTCACGACGTCCGAAGACAATCTGCCCGCGATCCTCAAACAGGTGAACGCCGGC
GGCAAGCTGTCGGTCACCGCGTACAACCGCAACAACACGGTGCCGCTCGAGACGGGCGCGCTCAACACGCTCGACAACCA
GATCGACACGGCGACGGGCACCGTGAAGCTGCGCGCGACGTTCGAGAACCGGAACAACCTGCTGTTCCCGAATCAGTTCG
TCAACACGCGGCTGCTCGTCGACACGATCCGCGACGCGACGATCGTGCCGACGTCGGCCGTGCTCTCGGGCTCGATCGGC
CAGTTCGTCTACGTCGTGAAGCCGGACAACACGGTGACCGTGCGCAAGGTAAAGCCCGGCCCCGTCGACGGCGAGCGCAC
GAGCATCGTCGAGGGGCTCGCCGTCGGCGAGCGGGTCGTGACGGACGGCTCCGACCGGTTGCGCGAAGGCTCGGCGGTCA
CGATCCCGGCCGACAAGCCGAAGCAGGCTTCGGGCGCAAAAAGCGCATCGGGCGCATCGGGCGCATCGGGCGCATCGGGC
GCACACGGCGGGCAGCGGCGCCGCGGCGCTTCGCAAGCCCAATCGCAATGA

Upstream 100 bases:

>100_bases
GCGCGAGTGCATCGCAAAGATCACGCGCGAGATCGGCGCCGCCGCGTGGCCGAATCGCGCCCGGTGAAATAGCGCAGCGC
GCCGGCCCGCGCCGTTCGGC

Downstream 100 bases:

>100_bases
CGCCGGCTGACCGATGAACCCGTCCCGCATCTTCATCCTTCGCCCGGTCGGCACCGCGCTCCTGATGGCGGCGATCATGC
TCGCCGGCCTCGTCGCGCTG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MPARWRRSPFARSPSPQPTPPHTLARRNSRQSERDPASRASAERSRRPPRVIAACHRPFTCNDRNSRKDRALDCNRHGDV
ASCNPAPQPARPALCVATGPQPARTAPAANAARARPSHALHADFQIEPMDNQEKPTPRSPAQPPSGSGPRRPRRKLIAFG
VLAAVAIGGVLWWHPWKSGGNPSTESRPDGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLS
GYLQSVSFQEGQIVKQGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLLAQDSIAKQTADTQASLVKQY
EGTVQIDRAAVDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDANGIVVITQLQPMSVIFTTSEDNLPAILKQVNAG
GKLSVTAYNRNNTVPLETGALNTLDNQIDTATGTVKLRATFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLSGSIG
QFVYVVKPDNTVTVRKVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGAKSASGASGASGASG
AHGGQRRRGASQAQSQ

Sequences:

>Translated_576_residues
MPARWRRSPFARSPSPQPTPPHTLARRNSRQSERDPASRASAERSRRPPRVIAACHRPFTCNDRNSRKDRALDCNRHGDV
ASCNPAPQPARPALCVATGPQPARTAPAANAARARPSHALHADFQIEPMDNQEKPTPRSPAQPPSGSGPRRPRRKLIAFG
VLAAVAIGGVLWWHPWKSGGNPSTESRPDGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLS
GYLQSVSFQEGQIVKQGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLLAQDSIAKQTADTQASLVKQY
EGTVQIDRAAVDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDANGIVVITQLQPMSVIFTTSEDNLPAILKQVNAG
GKLSVTAYNRNNTVPLETGALNTLDNQIDTATGTVKLRATFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLSGSIG
QFVYVVKPDNTVTVRKVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGAKSASGASGASGASG
AHGGQRRRGASQAQSQ
>Mature_575_residues
PARWRRSPFARSPSPQPTPPHTLARRNSRQSERDPASRASAERSRRPPRVIAACHRPFTCNDRNSRKDRALDCNRHGDVA
SCNPAPQPARPALCVATGPQPARTAPAANAARARPSHALHADFQIEPMDNQEKPTPRSPAQPPSGSGPRRPRRKLIAFGV
LAAVAIGGVLWWHPWKSGGNPSTESRPDGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLSG
YLQSVSFQEGQIVKQGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLLAQDSIAKQTADTQASLVKQYE
GTVQIDRAAVDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDANGIVVITQLQPMSVIFTTSEDNLPAILKQVNAGG
KLSVTAYNRNNTVPLETGALNTLDNQIDTATGTVKLRATFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLSGSIGQ
FVYVVKPDNTVTVRKVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGAKSASGASGASGASGA
HGGQRRRGASQAQSQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=359, Percent_Identity=46.7966573816156, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1789929, Length=331, Percent_Identity=30.5135951661631, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1786668, Length=326, Percent_Identity=34.3558282208589, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=33.6507936507937, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 61197; Mature: 61065

Theoretical pI: Translated: 11.10; Mature: 11.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARWRRSPFARSPSPQPTPPHTLARRNSRQSERDPASRASAERSRRPPRVIAACHRPFT
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCC
CNDRNSRKDRALDCNRHGDVASCNPAPQPARPALCVATGPQPARTAPAANAARARPSHAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCEE
HADFQIEPMDNQEKPTPRSPAQPPSGSGPRRPRRKLIAFGVLAAVAIGGVLWWHPWKSGG
ECCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCC
NPSTESRPDGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLS
CCCCCCCCCCCHHCCCCHHHHCCCCCCEEHHHCCCCCCCHHHHHHHHCCCCCEEEEHHHH
GYLQSVSFQEGQIVKQGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLL
HHHHHCCCCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AQDSIAKQTADTQASLVKQYEGTVQIDRAAVDSAKLNLAYARITAPVSGRVGLRQVDPGN
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHEEEEEEEEECCCCCCCCCEEECCCC
YVTPSDANGIVVITQLQPMSVIFTTSEDNLPAILKQVNAGGKLSVTAYNRNNTVPLETGA
EECCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCC
LNTLDNQIDTATGTVKLRATFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLSGSIG
CHHHHCHHCCCCCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHHCCCCC
QFVYVVKPDNTVTVRKVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKP
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCC
KQASGAKSASGASGASGASGAHGGQRRRGASQAQSQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCC
>Mature Secondary Structure 
PARWRRSPFARSPSPQPTPPHTLARRNSRQSERDPASRASAERSRRPPRVIAACHRPFT
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCC
CNDRNSRKDRALDCNRHGDVASCNPAPQPARPALCVATGPQPARTAPAANAARARPSHAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCEE
HADFQIEPMDNQEKPTPRSPAQPPSGSGPRRPRRKLIAFGVLAAVAIGGVLWWHPWKSGG
ECCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCC
NPSTESRPDGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLS
CCCCCCCCCCCHHCCCCHHHHCCCCCCEEHHHCCCCCCCHHHHHHHHCCCCCEEEEHHHH
GYLQSVSFQEGQIVKQGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLL
HHHHHCCCCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AQDSIAKQTADTQASLVKQYEGTVQIDRAAVDSAKLNLAYARITAPVSGRVGLRQVDPGN
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHEEEEEEEEECCCCCCCCCEEECCCC
YVTPSDANGIVVITQLQPMSVIFTTSEDNLPAILKQVNAGGKLSVTAYNRNNTVPLETGA
EECCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCC
LNTLDNQIDTATGTVKLRATFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLSGSIG
CHHHHCHHCCCCCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHHCCCCC
QFVYVVKPDNTVTVRKVKPGPVDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKP
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCC
KQASGAKSASGASGASGASGAHGGQRRRGASQAQSQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA