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The map label for this gene is kynB [H]

Identifier: 83720049

GI number: 83720049

Start: 820645

End: 821412

Strand: Reverse

Name: kynB [H]

Synonym: BTH_I0711

Alternate gene names: 83720049

Gene position: 821412-820645 (Counterclockwise)

Preceding gene: 83721388

Following gene: 83719525

Centisome position: 21.56

GC content: 68.75

Gene sequence:

>768_bases
TTGGTCTCCGTTTTAGATCTGTTTCGAATTATCTGCCATATCGGTGGATTGTCCATGCTTATTTCGCAAGCACCTGCTCC
GCAGGTTTGCCTATCATGCGAAACATTCGAGGCTTTTCGACAACGCATGGACACGATCTGGGACATCTCCCCGCCAATCG
CCCCCGCGACGCCCGTCTGGCCGGGCGACACGCCCGTCGGCATCGAGCGGGTGTGGCGCATCGAGGCGGGCTCGCCCGTC
AACGTCGCGCGCATCACGCTGTCGCCGCACACCGGCGCGCACGCGGATGCGCCGCTGCATTACGACGCCCATGGCGCGCC
GATCGGCGCGGTGCCGCTCGACGCGTATCTCGGCCGCTGCCGCGTGATCCATTGCATCGGCGCGCATCCCGTCGTCTCGC
CCGACGATGTGCGCGCGGCGCTCGCCGACGCGCCGCCGCGCGTGCTGCTGCGCACCTACGGCCAGGCGCCGCAGCGCGCG
TGGGACAGCGCGTTCTGCGCGGTCGCGCCGCAGACGATCGATCTGCTCGCCGCGCACGGCGTGCGCCTCGTCGGCATCGA
CACGCCGTCGCTCGACCCGCAGGAATCGAAGACGATGGACGCGCACCGGCGCATTCGCGCGCACGGGATGGCGATTCTCG
AAGGCCTCGTGCTCGACGAAATCGCCGCCGGCGACTACGAGCTGATCGCACTGCCGCTGAAATTCGCGACGCTCGATGCA
AGCCCCGTGCGCGCGGTGCTGCGCGCGCTGCCCGACGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
GAAATGCGCTCGGCCAGATCGAGGTTGCTGATCCGTCCTTCCTGCTGAAGGACCGCGAGAATACGGCAATCGGTTGCATC
CAGCGTGATCGCATGCATTT

Downstream 100 bases:

>100_bases
AGAAAAGCGGACGCGATCGCCCCTCCCCCAACCAGGTTCGACATCATGAAAACACGTGAAGAAGCGCTCGCGCTCGATCG
CGACGACCCGCTCGCGCCAT

Product: cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVSVLDLFRIICHIGGLSMLISQAPAPQVCLSCETFEAFRQRMDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPV
NVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRCRVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRA
WDSAFCAVAPQTIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDA
SPVRAVLRALPDAPR

Sequences:

>Translated_255_residues
MVSVLDLFRIICHIGGLSMLISQAPAPQVCLSCETFEAFRQRMDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPV
NVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRCRVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRA
WDSAFCAVAPQTIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDA
SPVRAVLRALPDAPR
>Mature_255_residues
MVSVLDLFRIICHIGGLSMLISQAPAPQVCLSCETFEAFRQRMDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPV
NVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRCRVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRA
WDSAFCAVAPQTIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDA
SPVRAVLRALPDAPR

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 27342; Mature: 27342

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVLDLFRIICHIGGLSMLISQAPAPQVCLSCETFEAFRQRMDTIWDISPPIAPATPVW
CCHHHHHHHHHHHHCCHHHHHHCCCCCHHEECHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGDTPVGIERVWRIEAGSPVNVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRC
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHCCE
RVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRAWDSAFCAVAPQTIDLLAAHG
EEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCC
VRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCC
SPVRAVLRALPDAPR
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MVSVLDLFRIICHIGGLSMLISQAPAPQVCLSCETFEAFRQRMDTIWDISPPIAPATPVW
CCHHHHHHHHHHHHCCHHHHHHCCCCCHHEECHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGDTPVGIERVWRIEAGSPVNVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRC
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHCCE
RVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRAWDSAFCAVAPQTIDLLAAHG
EEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCC
VRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCC
SPVRAVLRALPDAPR
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA