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The map label for this gene is pcaK [H]

Identifier: 83719097

GI number: 83719097

Start: 816876

End: 818270

Strand: Direct

Name: pcaK [H]

Synonym: BTH_I0708

Alternate gene names: 83719097

Gene position: 816876-818270 (Clockwise)

Preceding gene: 83721267

Following gene: 83718642

Centisome position: 21.44

GC content: 72.97

Gene sequence:

>1395_bases
ATGAGCGCCCGCCGCGGCAGCGCGCCGCTCGCGGTCGACATCGGCGCGACGCTCGACCACGGCCCGTTCACCGCAATGCA
GCGCGTCGCGGTGCTGCTCGCCGCGTTCTCGATCGTGCTCGACGGCTTCGACAGCCAGTTGATCGGCTTCGCGATTCCGG
TGCTGATCAAGGAGTGGGGGATCACGCGCGATGCATTCGCGCCCGCCGTCGCGGCGGGCCTGTTCGGAATGGGCGTCGGC
AGCGCATGCGCGGGCCTGTTCGCGGACCGCTTCGGCAGGCGCTGGGCGATCATCGGCAGCGTGTTCGTGTTCGGCGCGGC
GACCTGCGCGATCGGCTTCGCGCCGAATGTCGCGACCATCGCCGCGCTGCGCTTCTTCGCGGGCCTCGGGATCGGCGGCG
CGCTGCCCACCGCGGCGACGATGACGGCCGAATACACGCCCGCGCGCCGCCGCACGATGATGGTGACCGCGACGATCGTC
TGCGTGCCGGCGGGCGGGATGCTTGCCGGCCTTTTCGCGCACGAGGTGCTGCCCGCATACGGCTGGCGCGGCCTGTTCTG
GCTCGGCGGCGCGTTGCCGTTCGCGCTCGGCCTGCTGCTCGTGCGCGCGCTGCCCGAATCGCCGCGCTATCTGGCGCGCG
ATCCGGCGCGCTGGCGCGAGCTCGGCGCGCTGCTCGCGCGAATGGGGCGGCCCGTCGCGGCGGGCACCGCGTTCACCGAT
CTGGCCGAAGCGCGCGCGCACGAAGGGCAGCGGCGCGGCGTGCGCGCGCTGTTCTCGGCCGCCTACGCGCGCGACACGAT
CGCATTGTGGTGTGCGTTCTGCATGTGCCTGCTCGCGGTCTACAGCGCATTCAGCTGGCTGCCGACGATGCTGACGTCGC
AAGGCTTGAGCGTGTCGGTGGCGGGCTCCGGGCTTACCGCGTACAACCTCGGCGGCGTCGTGGGCGCGCTCGGCTGCGCG
TTCGCGATCGGGCGCTTCGGCTCGCGCTGGCCGCTCGCGTTTTGCTGCGCGGGCGGCGCGGCGAGCGCCGCGTGGCTGCT
CGGCGTCGATGCGGCAAGCCACACCGGCTGGCTGATCGCGGGCCTCGCCGCGCACGGCTTCTTCGTGAACGCGGTGCAAT
CGACGATGTACGCGCTCTGCACGTACATCTATCCGACGCCCGTGCGCGCGACGGGCGCCGCCAGCGCCGTCGCGTTCGGC
CGCGTCGGCGCGATTCTGAGCGCGTTCGCGGGCGCGTACGTGATCTCGGCGGGCGGCGCGAACGCGTATCTGACGATGCT
GACCGTTGCGATGGCGGTCGTGCTTTTCGCGTTGCTCGCGCTGCGCCGGCACATTCCGCGCTTGCGCCGCGGCGGGCTGC
CGGCGAGCGACGAGCTCGCGCGCGCGGCCCCCTGA

Upstream 100 bases:

>100_bases
GAGGACATTCAGGAGACGACATGAAGCACACCCCGACCCCGTGTTTCGCCGCGGCGCGCCGCCGCATCCGCCGCTCGAGC
GGCGCGCGCCGGAGGCTCGC

Downstream 100 bases:

>100_bases
CGTTCCGACGCTTCGCCGCCCGCCCGCGTGCGTGTGTGCGGCGGGCGCGCGCTACAGCGTCGTGCGCACGTGCCAGAGCT
CGGGGAACAGCACGACGTCG

Product: 4-hydroxybenzoate transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSARRGSAPLAVDIGATLDHGPFTAMQRVAVLLAAFSIVLDGFDSQLIGFAIPVLIKEWGITRDAFAPAVAAGLFGMGVG
SACAGLFADRFGRRWAIIGSVFVFGAATCAIGFAPNVATIAALRFFAGLGIGGALPTAATMTAEYTPARRRTMMVTATIV
CVPAGGMLAGLFAHEVLPAYGWRGLFWLGGALPFALGLLLVRALPESPRYLARDPARWRELGALLARMGRPVAAGTAFTD
LAEARAHEGQRRGVRALFSAAYARDTIALWCAFCMCLLAVYSAFSWLPTMLTSQGLSVSVAGSGLTAYNLGGVVGALGCA
FAIGRFGSRWPLAFCCAGGAASAAWLLGVDAASHTGWLIAGLAAHGFFVNAVQSTMYALCTYIYPTPVRATGAASAVAFG
RVGAILSAFAGAYVISAGGANAYLTMLTVAMAVVLFALLALRRHIPRLRRGGLPASDELARAAP

Sequences:

>Translated_464_residues
MSARRGSAPLAVDIGATLDHGPFTAMQRVAVLLAAFSIVLDGFDSQLIGFAIPVLIKEWGITRDAFAPAVAAGLFGMGVG
SACAGLFADRFGRRWAIIGSVFVFGAATCAIGFAPNVATIAALRFFAGLGIGGALPTAATMTAEYTPARRRTMMVTATIV
CVPAGGMLAGLFAHEVLPAYGWRGLFWLGGALPFALGLLLVRALPESPRYLARDPARWRELGALLARMGRPVAAGTAFTD
LAEARAHEGQRRGVRALFSAAYARDTIALWCAFCMCLLAVYSAFSWLPTMLTSQGLSVSVAGSGLTAYNLGGVVGALGCA
FAIGRFGSRWPLAFCCAGGAASAAWLLGVDAASHTGWLIAGLAAHGFFVNAVQSTMYALCTYIYPTPVRATGAASAVAFG
RVGAILSAFAGAYVISAGGANAYLTMLTVAMAVVLFALLALRRHIPRLRRGGLPASDELARAAP
>Mature_463_residues
SARRGSAPLAVDIGATLDHGPFTAMQRVAVLLAAFSIVLDGFDSQLIGFAIPVLIKEWGITRDAFAPAVAAGLFGMGVGS
ACAGLFADRFGRRWAIIGSVFVFGAATCAIGFAPNVATIAALRFFAGLGIGGALPTAATMTAEYTPARRRTMMVTATIVC
VPAGGMLAGLFAHEVLPAYGWRGLFWLGGALPFALGLLLVRALPESPRYLARDPARWRELGALLARMGRPVAAGTAFTDL
AEARAHEGQRRGVRALFSAAYARDTIALWCAFCMCLLAVYSAFSWLPTMLTSQGLSVSVAGSGLTAYNLGGVVGALGCAF
AIGRFGSRWPLAFCCAGGAASAAWLLGVDAASHTGWLIAGLAAHGFFVNAVQSTMYALCTYIYPTPVRATGAASAVAFGR
VGAILSAFAGAYVISAGGANAYLTMLTVAMAVVLFALLALRRHIPRLRRGGLPASDELARAAP

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=412, Percent_Identity=24.7572815533981, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI213021148, Length=435, Percent_Identity=24.5977011494253, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081723, Length=338, Percent_Identity=31.6568047337278, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786229, Length=438, Percent_Identity=24.8858447488584, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082231, Length=179, Percent_Identity=31.2849162011173, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082404, Length=417, Percent_Identity=21.8225419664269, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788068, Length=433, Percent_Identity=23.3256351039261, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082159, Length=384, Percent_Identity=26.3020833333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788074, Length=376, Percent_Identity=23.6702127659574, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789207, Length=222, Percent_Identity=28.8288288288288, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=392, Percent_Identity=27.0408163265306, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19922874, Length=402, Percent_Identity=22.8855721393035, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47997; Mature: 47866

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRGSAPLAVDIGATLDHGPFTAMQRVAVLLAAFSIVLDGFDSQLIGFAIPVLIKEWG
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ITRDAFAPAVAAGLFGMGVGSACAGLFADRFGRRWAIIGSVFVFGAATCAIGFAPNVATI
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AALRFFAGLGIGGALPTAATMTAEYTPARRRTMMVTATIVCVPAGGMLAGLFAHEVLPAY
HHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHEEEEEEEEEEECCCHHHHHHHHHHHHHHC
GWRGLFWLGGALPFALGLLLVRALPESPRYLARDPARWRELGALLARMGRPVAAGTAFTD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
LAEARAHEGQRRGVRALFSAAYARDTIALWCAFCMCLLAVYSAFSWLPTMLTSQGLSVSV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AGSGLTAYNLGGVVGALGCAFAIGRFGSRWPLAFCCAGGAASAAWLLGVDAASHTGWLIA
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHEECCCCCCCCHHHH
GLAAHGFFVNAVQSTMYALCTYIYPTPVRATGAASAVAFGRVGAILSAFAGAYVISAGGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCC
NAYLTMLTVAMAVVLFALLALRRHIPRLRRGGLPASDELARAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure 
SARRGSAPLAVDIGATLDHGPFTAMQRVAVLLAAFSIVLDGFDSQLIGFAIPVLIKEWG
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ITRDAFAPAVAAGLFGMGVGSACAGLFADRFGRRWAIIGSVFVFGAATCAIGFAPNVATI
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AALRFFAGLGIGGALPTAATMTAEYTPARRRTMMVTATIVCVPAGGMLAGLFAHEVLPAY
HHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHEEEEEEEEEEECCCHHHHHHHHHHHHHHC
GWRGLFWLGGALPFALGLLLVRALPESPRYLARDPARWRELGALLARMGRPVAAGTAFTD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
LAEARAHEGQRRGVRALFSAAYARDTIALWCAFCMCLLAVYSAFSWLPTMLTSQGLSVSV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AGSGLTAYNLGGVVGALGCAFAIGRFGSRWPLAFCCAGGAASAAWLLGVDAASHTGWLIA
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHEECCCCCCCCHHHH
GLAAHGFFVNAVQSTMYALCTYIYPTPVRATGAASAVAFGRVGAILSAFAGAYVISAGGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCC
NAYLTMLTVAMAVVLFALLALRRHIPRLRRGGLPASDELARAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]