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The map label for this gene is panE-1 [H]

Identifier: 83721267

GI number: 83721267

Start: 815282

End: 816214

Strand: Direct

Name: panE-1 [H]

Synonym: BTH_I0707

Alternate gene names: 83721267

Gene position: 815282-816214 (Clockwise)

Preceding gene: 83720754

Following gene: 83719097

Centisome position: 21.4

GC content: 73.63

Gene sequence:

>933_bases
ATGAAAATCGCGATGCTCGGCGCGGGCGCGATGGGCTCGCTGTTCGGCGGATGGCTCGCCGAGGGCGGGCACGACGTGAC
GCTCGTCGACGTGAACGCCGCGCATGTCGACGCGATCGCGCGCGACGGACTGCGGCTCGACACCGATCGCGGCGAGCGGC
GCGTCGCGCGGCTCGCCGCGCTGCGGCCGGACGGCGTCGCGGCGCTCGCCGGCGCGCCGCCCGACCTGGTGATCGTGTTC
ACGAAGACGCTGCACACGCGCGCGGCGCTCGCGGGCGCGCGCGCGCTCTTCGGCCCGCACACGTGCGTGCTGACGCTGCA
GAACGGGCTCGGCAATGTCGAGGTGCTCGCAGAATGCGTGCCGCGCGAGCGGATTCTCGTCGGCGTGACGACGTGGCCGG
CCGATCTTGCCGGGCCCGGGCACGTGCGCTCGCACGGCGCGGGCTGGGTCAGGCTGATGAGCGCGGACGGCGCGATGCGG
CCGATCGTGCAGGCGAGCGCGGACGCGCTCGATCGCGCGGGCCTGAACTGCACGGTCGACGCGGGCGTGTGGGCGACGAT
CTGGGAGAAGGTGGGCTTCAACGCGGCGCTCAATACGCTGTGCGCGGTCACGCGCTGCACGGTCGATGCGCTCGGCGCGC
GCGAGGACGGGCCGGCGCTCGCGATCGCGATCGTCGCGGAAGTGGCGGCGGTCGCCCGCGCGAAGGGCATCGAAGTCGAC
GGGCGCAGGATGCGCGAGAACGTGCTGCACGCGATCGGCGAGCATCGCGGCCATCGCCCGTCGATGCTGCAGGACGTGCT
CGCGGGGCGGCGCACGGAGATCGAATCGATCAACGGCGCGGTGGTCGCGGCGGCGCGTGAGCTCGGCGTCGCGACCCCGC
ATGTGGAGACGCTGCTGCGGCTCGTCAGGCTGATCGACGCGCGGGTGGGGTAA

Upstream 100 bases:

>100_bases
CCACTTCGGCGGCAAAGCGGGCATCGCCGAATTCACCGATCTGCGCTGGATCACCGTGCAGACGGCGCCGCGCCACTATC
CGTTCTGAACGATGGCGACG

Downstream 100 bases:

>100_bases
CGCGGCGGATGCGACGAAGCGGGCGTGGCGCGAACGAAATCGCGCGAAGGCGTCCGCACGGCCGCCATGAGGGCAGGACG
CCATGACGGCATCGCGGTGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKIAMLGAGAMGSLFGGWLAEGGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAALAGAPPDLVIVF
TKTLHTRAALAGARALFGPHTCVLTLQNGLGNVEVLAECVPRERILVGVTTWPADLAGPGHVRSHGAGWVRLMSADGAMR
PIVQASADALDRAGLNCTVDAGVWATIWEKVGFNAALNTLCAVTRCTVDALGAREDGPALAIAIVAEVAAVARAKGIEVD
GRRMRENVLHAIGEHRGHRPSMLQDVLAGRRTEIESINGAVVAAARELGVATPHVETLLRLVRLIDARVG

Sequences:

>Translated_310_residues
MKIAMLGAGAMGSLFGGWLAEGGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAALAGAPPDLVIVF
TKTLHTRAALAGARALFGPHTCVLTLQNGLGNVEVLAECVPRERILVGVTTWPADLAGPGHVRSHGAGWVRLMSADGAMR
PIVQASADALDRAGLNCTVDAGVWATIWEKVGFNAALNTLCAVTRCTVDALGAREDGPALAIAIVAEVAAVARAKGIEVD
GRRMRENVLHAIGEHRGHRPSMLQDVLAGRRTEIESINGAVVAAARELGVATPHVETLLRLVRLIDARVG
>Mature_310_residues
MKIAMLGAGAMGSLFGGWLAEGGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAALAGAPPDLVIVF
TKTLHTRAALAGARALFGPHTCVLTLQNGLGNVEVLAECVPRERILVGVTTWPADLAGPGHVRSHGAGWVRLMSADGAMR
PIVQASADALDRAGLNCTVDAGVWATIWEKVGFNAALNTLCAVTRCTVDALGAREDGPALAIAIVAEVAAVARAKGIEVD
GRRMRENVLHAIGEHRGHRPSMLQDVLAGRRTEIESINGAVVAAARELGVATPHVETLLRLVRLIDARVG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=306, Percent_Identity=28.1045751633987, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320057, Length=346, Percent_Identity=25.7225433526012, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32397; Mature: 32397

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAMLGAGAMGSLFGGWLAEGGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAA
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCEECCCCHHHHHHHHHH
LRPDGVAALAGAPPDLVIVFTKTLHTRAALAGARALFGPHTCVLTLQNGLGNVEVLAECV
CCCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHC
PRERILVGVTTWPADLAGPGHVRSHGAGWVRLMSADGAMRPIVQASADALDRAGLNCTVD
CCCEEEEEEEECCHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEC
AGVWATIWEKVGFNAALNTLCAVTRCTVDALGAREDGPALAIAIVAEVAAVARAKGIEVD
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GRRMRENVLHAIGEHRGHRPSMLQDVLAGRRTEIESINGAVVAAARELGVATPHVETLLR
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCCHHEEHHHHHCCCCCCHHHHHH
LVRLIDARVG
HHHHHHHCCC
>Mature Secondary Structure
MKIAMLGAGAMGSLFGGWLAEGGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAA
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCEECCCCHHHHHHHHHH
LRPDGVAALAGAPPDLVIVFTKTLHTRAALAGARALFGPHTCVLTLQNGLGNVEVLAECV
CCCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHC
PRERILVGVTTWPADLAGPGHVRSHGAGWVRLMSADGAMRPIVQASADALDRAGLNCTVD
CCCEEEEEEEECCHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEC
AGVWATIWEKVGFNAALNTLCAVTRCTVDALGAREDGPALAIAIVAEVAAVARAKGIEVD
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GRRMRENVLHAIGEHRGHRPSMLQDVLAGRRTEIESINGAVVAAARELGVATPHVETLLR
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCCHHEEHHHHHCCCCCCHHHHHH
LVRLIDARVG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]