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The map label for this gene is ywlC [H]

Identifier: 83719082

GI number: 83719082

Start: 767501

End: 768526

Strand: Direct

Name: ywlC [H]

Synonym: BTH_I0669

Alternate gene names: 83719082

Gene position: 767501-768526 (Clockwise)

Preceding gene: 83720003

Following gene: 83718618

Centisome position: 20.15

GC content: 73.2

Gene sequence:

>1026_bases
ATGTCGAACGATCGACCGATTCCGACCGACGAGCAGATCGACGAAGCCGCCGCGCTGCTCGACGCGGGCGAACTCGTCGC
GTTTCCGACCGAAACCGTCTACGGGCTCGGCGGCGACGCGCAGAACCCGGCCGCCGTCGCGCGCATCTACGCGGCGAAAG
GGCGGCCGGCGAACCATCCGGTGATCGTCCACCTCGCGCCGGGCAGCGATCCGGGCTACTGGGTCGATTCGTTGCCCGCC
GACGCGCAGAAGTTGATCGACGCGTTCTGGCCCGGCCCGCTCACGCTGATCCTCAAGCGCGCCGCGCGTATTCCGGACGC
GGTGAGCGGCGGGCAGGACTCGGTCGGCTTGCGCTGCCCGTCGCATCCGGTCGCGCAGGCGCTGCTGCGTGCGTTCGACG
CGCGTCGCGGCGGGCACGGCGGCGTCGCCGCGCCGTCGGCGAACCGTTTCGGCCACGTGAGCCCGACCACCGCGCAGCAC
GTGCGCGACGAATTCGGCGATGCCGTCCGCGTGCTCGACGGCGGCCCGTCCGACGTCGGGATCGAATCGACGATTCTCGA
TTTGTCGCGCGGTTTTCCGGCGCTGTTGCGCCCGGGCGACGTGAGCCCGCGGCAGATCGCCGATGTGCTCGGCGTCGCGC
CGCGCCTGCCCGACGGCAGCGATGCGACCGCGCCGCGCGCGTCCGGCACGTTGAAGGCGCATTACGCACCGCGCACGCCG
CTCGCGCTGGCGGCGTTCGAGCGGCTCGAGCCGCTGCTCGCGGCCGCGCGCGACGCCGGCAAACCGGTGGCGCTCGTCGC
GCGCGTGTCGCGCGCGGGCGCGTGGGCGCACGCACAGGGCGTGCATTTCGTCGCGGCGCCCGAGGACCCGCGAGTCTACG
CGCGTGAGCTCTACGGGCTGCTGCGCGCGCTCGACCGCGCGCAGGTCGCGCGCATTCTCGTCGAGAAGCTGCCGGATACG
GTCGAATGGATCGCGGTGAACGACCGGCTCGGCCGTGCGGCGGCCGCGTTCGACGCGCAGGAGTGA

Upstream 100 bases:

>100_bases
GCCACGTGAACTTCACCGCGGCGACGCTCGACGAAGCGGTCGCGGGCGCGACCGCGTGCGCGCGGCTGTTGCGCATTCCG
CTCGACTGACGGAGCGCGAG

Downstream 100 bases:

>100_bases
GCGTCGGGCGGTTCGGCGGCTGATTCGGCGGGTGAAGCCGAGCATGTCTTCGTTATGCTCTGGCCGCCGAAACGCCGAAA
CGCCGAAACGCCGAAACGCC

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSNDRPIPTDEQIDEAAALLDAGELVAFPTETVYGLGGDAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVDSLPA
DAQKLIDAFWPGPLTLILKRAARIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDAVRVLDGGPSDVGIESTILDLSRGFPALLRPGDVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
LALAAFERLEPLLAAARDAGKPVALVARVSRAGAWAHAQGVHFVAAPEDPRVYARELYGLLRALDRAQVARILVEKLPDT
VEWIAVNDRLGRAAAAFDAQE

Sequences:

>Translated_341_residues
MSNDRPIPTDEQIDEAAALLDAGELVAFPTETVYGLGGDAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVDSLPA
DAQKLIDAFWPGPLTLILKRAARIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDAVRVLDGGPSDVGIESTILDLSRGFPALLRPGDVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
LALAAFERLEPLLAAARDAGKPVALVARVSRAGAWAHAQGVHFVAAPEDPRVYARELYGLLRALDRAQVARILVEKLPDT
VEWIAVNDRLGRAAAAFDAQE
>Mature_340_residues
SNDRPIPTDEQIDEAAALLDAGELVAFPTETVYGLGGDAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVDSLPAD
AQKLIDAFWPGPLTLILKRAARIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHV
RDEFGDAVRVLDGGPSDVGIESTILDLSRGFPALLRPGDVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTPL
ALAAFERLEPLLAAARDAGKPVALVARVSRAGAWAHAQGVHFVAAPEDPRVYARELYGLLRALDRAQVARILVEKLPDTV
EWIAVNDRLGRAAAAFDAQE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=197, Percent_Identity=31.9796954314721, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI2367210, Length=164, Percent_Identity=31.0975609756098, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17537239, Length=182, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=379, Percent_Identity=30.6068601583113, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI78707274, Length=203, Percent_Identity=27.0935960591133, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35832; Mature: 35701

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDRPIPTDEQIDEAAALLDAGELVAFPTETVYGLGGDAQNPAAVARIYAAKGRPANHP
CCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEECCCCCCCHHHHHHHHHHCCCCCCCC
VIVHLAPGSDPGYWVDSLPADAQKLIDAFWPGPLTLILKRAARIPDAVSGGQDSVGLRCP
EEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCC
SHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDAVRVLDGGPSDVG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCC
IESTILDLSRGFPALLRPGDVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LALAAFERLEPLLAAARDAGKPVALVARVSRAGAWAHAQGVHFVAAPEDPRVYARELYGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHHHHHHH
LRALDRAQVARILVEKLPDTVEWIAVNDRLGRAAAAFDAQE
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHCHHHHHCCCCC
>Mature Secondary Structure 
SNDRPIPTDEQIDEAAALLDAGELVAFPTETVYGLGGDAQNPAAVARIYAAKGRPANHP
CCCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEECCCCCCCHHHHHHHHHHCCCCCCCC
VIVHLAPGSDPGYWVDSLPADAQKLIDAFWPGPLTLILKRAARIPDAVSGGQDSVGLRCP
EEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCC
SHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDAVRVLDGGPSDVG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCC
IESTILDLSRGFPALLRPGDVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LALAAFERLEPLLAAARDAGKPVALVARVSRAGAWAHAQGVHFVAAPEDPRVYARELYGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHHHHHHH
LRALDRAQVARILVEKLPDTVEWIAVNDRLGRAAAAFDAQE
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]