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The map label for this gene is atoC [H]

Identifier: 83594434

GI number: 83594434

Start: 3574071

End: 3575417

Strand: Direct

Name: atoC [H]

Synonym: Rru_A3104

Alternate gene names: 83594434

Gene position: 3574071-3575417 (Clockwise)

Preceding gene: 83594433

Following gene: 83594435

Centisome position: 82.11

GC content: 64.44

Gene sequence:

>1347_bases
ATGACCGAACCGCTCCCCCGCCTGCTGATCGTCGAGGATGATCTGGGTGTGCAGTCCCAGCTCAAGTGGAGCTTCTCCGA
CGAGTGGCTGATCGATGTCGCCGCCGATCGGGCCAAGGCGCTCGAGATCGCCGCGCGCACCCCGCCGACCATCGTCATCC
TCGATCTAGGCCTGCCCCCCGAGCCCAATGGCGCGGGCGAGGGGCTGGCGACCCTGGAAGGGCTGATCTCGCTTAATCCG
CTGACCAAGGTCATCGTCTCAAGCGGCAATGAGGACCACCGCCATGCCCTGTCGGCCATTCGCCTGGGGGCCTATGATTT
CTATCCCAAGCCGGTCGACATCGAGCATCTGCGGCTGATCACCGCCCGGGCGGCCCATCTGCGCCGCCTTGAAGAGGAAA
ACCGCCAGCTCGCCCGCGCCGGCCACGCCGGTCCCTTGGCCAATGTCATCGGCGAAAGCGCCGCCATCCAAGCGGTCTGC
CAGATGGTGCGCCGCGTCGCCTCGACCACGGTGAACGTGCTGTTGCTAGGCGAAAGCGGCACCGGCAAAGAGGTTTTCGC
CCATTCCCTCCATCAGCTCAGCGGCCGCGCCGGCCAACCCTTCGTCGCCATCAACTGCGCGGCCATCCCCGAAAACCTGC
TTGAAAGCGAGTTGTTCGGCCACGAGAAGGGCGCCTTCACCGGGGCCTTGCGCCAGACCACCGGCAAGATCCAGCAGGCC
AATGGCGGAACCCTGTTCCTTGATGAAATCGGCGATATGCCGCCACCCCTTCAGGCCAAGTTGCTGCGCTTCCTGCAAAG
CCGGGTGATCGAGCGGGTCGGCGGCCGGCAAAGCCTGGAGGTCGATGTCCGCATCGTTTCGGCCACCAACCGCGATCTTG
GCGCCTTGATCGAAAAGGGCGAGTTCCGCGAGGATCTTTATTACCGCCTCGACGAGGTGAAGATCGCCCTGCCGCCTTTG
CGCGACCGCATCGAAGACGCCCCCCTGCTCGCCCAGTATTTTCTCGATTCCTTCGCCGCCAGCATGGGCCGCAAGGTGAC
CGGCTTCAGCTCCGACGCCCAGGTCGCCCTGTCGGCCCATCCCTGGCCGGGCAATGTCCGCGAACTGGAAAACCGGGTGA
AACGGGCGGTGGTTCTGGCCGAGGGACGGCTGGTGACCGCCAAGGATATGGATCTGGTCGGCGGCGCCATGCCCACCCTG
CGCGAGAGCCGCCGTCGGGCCGATTATCAGGCGGTCACCACCGCCCTGTTGCTGGCGGGCAATAATCTTTCGCTGGCGGC
CAAGTATCTCGGCATCAGCCGACCGACTTTATACGACTTGATCGAGACCCATAACATTCACGTTTAA

Upstream 100 bases:

>100_bases
GCATGGGCGGACAGTTGACCGTCACCTCCGACCGGGGACGGGGCACCCGCATGACCGTGTTGCTGCCCGATAGGACCGCC
CAGGCCCGCCGAGGTGCGGC

Downstream 100 bases:

>100_bases
TGACCCCGGGACATCAGGCCGGGACATCAGGACTGTTCAGTGATGGCCGATATTCTTTTCCTGTGCCAGCGCATCCCCTT
CCCTCCCACAAAGGGGGACA

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTEPLPRLLIVEDDLGVQSQLKWSFSDEWLIDVAADRAKALEIAARTPPTIVILDLGLPPEPNGAGEGLATLEGLISLNP
LTKVIVSSGNEDHRHALSAIRLGAYDFYPKPVDIEHLRLITARAAHLRRLEEENRQLARAGHAGPLANVIGESAAIQAVC
QMVRRVASTTVNVLLLGESGTGKEVFAHSLHQLSGRAGQPFVAINCAAIPENLLESELFGHEKGAFTGALRQTTGKIQQA
NGGTLFLDEIGDMPPPLQAKLLRFLQSRVIERVGGRQSLEVDVRIVSATNRDLGALIEKGEFREDLYYRLDEVKIALPPL
RDRIEDAPLLAQYFLDSFAASMGRKVTGFSSDAQVALSAHPWPGNVRELENRVKRAVVLAEGRLVTAKDMDLVGGAMPTL
RESRRRADYQAVTTALLLAGNNLSLAAKYLGISRPTLYDLIETHNIHV

Sequences:

>Translated_448_residues
MTEPLPRLLIVEDDLGVQSQLKWSFSDEWLIDVAADRAKALEIAARTPPTIVILDLGLPPEPNGAGEGLATLEGLISLNP
LTKVIVSSGNEDHRHALSAIRLGAYDFYPKPVDIEHLRLITARAAHLRRLEEENRQLARAGHAGPLANVIGESAAIQAVC
QMVRRVASTTVNVLLLGESGTGKEVFAHSLHQLSGRAGQPFVAINCAAIPENLLESELFGHEKGAFTGALRQTTGKIQQA
NGGTLFLDEIGDMPPPLQAKLLRFLQSRVIERVGGRQSLEVDVRIVSATNRDLGALIEKGEFREDLYYRLDEVKIALPPL
RDRIEDAPLLAQYFLDSFAASMGRKVTGFSSDAQVALSAHPWPGNVRELENRVKRAVVLAEGRLVTAKDMDLVGGAMPTL
RESRRRADYQAVTTALLLAGNNLSLAAKYLGISRPTLYDLIETHNIHV
>Mature_447_residues
TEPLPRLLIVEDDLGVQSQLKWSFSDEWLIDVAADRAKALEIAARTPPTIVILDLGLPPEPNGAGEGLATLEGLISLNPL
TKVIVSSGNEDHRHALSAIRLGAYDFYPKPVDIEHLRLITARAAHLRRLEEENRQLARAGHAGPLANVIGESAAIQAVCQ
MVRRVASTTVNVLLLGESGTGKEVFAHSLHQLSGRAGQPFVAINCAAIPENLLESELFGHEKGAFTGALRQTTGKIQQAN
GGTLFLDEIGDMPPPLQAKLLRFLQSRVIERVGGRQSLEVDVRIVSATNRDLGALIEKGEFREDLYYRLDEVKIALPPLR
DRIEDAPLLAQYFLDSFAASMGRKVTGFSSDAQVALSAHPWPGNVRELENRVKRAVVLAEGRLVTAKDMDLVGGAMPTLR
ESRRRADYQAVTTALLLAGNNLSLAAKYLGISRPTLYDLIETHNIHV

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=456, Percent_Identity=39.6929824561403, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI1790437, Length=449, Percent_Identity=39.4209354120267, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1790299, Length=385, Percent_Identity=41.038961038961, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1788905, Length=451, Percent_Identity=36.5853658536585, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI87082117, Length=255, Percent_Identity=52.156862745098, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1789087, Length=248, Percent_Identity=49.1935483870968, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789233, Length=244, Percent_Identity=50.4098360655738, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=48.9270386266094, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=323, Percent_Identity=39.938080495356, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787583, Length=300, Percent_Identity=38.3333333333333, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=40.5750798722045, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789828, Length=266, Percent_Identity=34.9624060150376, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=29.6928327645051, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48826; Mature: 48694

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPLPRLLIVEDDLGVQSQLKWSFSDEWLIDVAADRAKALEIAARTPPTIVILDLGLPP
CCCCCCCEEEEECCCCCCHHEEECCCCCEEEEEHHHHHHHHEEECCCCCEEEEEECCCCC
EPNGAGEGLATLEGLISLNPLTKVIVSSGNEDHRHALSAIRLGAYDFYPKPVDIEHLRLI
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCCHHHHHHH
TARAAHLRRLEEENRQLARAGHAGPLANVIGESAAIQAVCQMVRRVASTTVNVLLLGESG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEEEECCC
TGKEVFAHSLHQLSGRAGQPFVAINCAAIPENLLESELFGHEKGAFTGALRQTTGKIQQA
CCHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEC
NGGTLFLDEIGDMPPPLQAKLLRFLQSRVIERVGGRQSLEVDVRIVSATNRDLGALIEKG
CCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHCC
EFREDLYYRLDEVKIALPPLRDRIEDAPLLAQYFLDSFAASMGRKVTGFSSDAQVALSAH
CHHHHHHHHHHHHEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECC
PWPGNVRELENRVKRAVVLAEGRLVTAKDMDLVGGAMPTLRESRRRADYQAVTTALLLAG
CCCCCHHHHHHHHHHEEEEECCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
NNLSLAAKYLGISRPTLYDLIETHNIHV
CCHHHHHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TEPLPRLLIVEDDLGVQSQLKWSFSDEWLIDVAADRAKALEIAARTPPTIVILDLGLPP
CCCCCCEEEEECCCCCCHHEEECCCCCEEEEEHHHHHHHHEEECCCCCEEEEEECCCCC
EPNGAGEGLATLEGLISLNPLTKVIVSSGNEDHRHALSAIRLGAYDFYPKPVDIEHLRLI
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCCHHHHHHH
TARAAHLRRLEEENRQLARAGHAGPLANVIGESAAIQAVCQMVRRVASTTVNVLLLGESG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEEEECCC
TGKEVFAHSLHQLSGRAGQPFVAINCAAIPENLLESELFGHEKGAFTGALRQTTGKIQQA
CCHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEC
NGGTLFLDEIGDMPPPLQAKLLRFLQSRVIERVGGRQSLEVDVRIVSATNRDLGALIEKG
CCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHCC
EFREDLYYRLDEVKIALPPLRDRIEDAPLLAQYFLDSFAASMGRKVTGFSSDAQVALSAH
CHHHHHHHHHHHHEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECC
PWPGNVRELENRVKRAVVLAEGRLVTAKDMDLVGGAMPTLRESRRRADYQAVTTALLLAG
CCCCCHHHHHHHHHHEEEEECCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
NNLSLAAKYLGISRPTLYDLIETHNIHV
CCHHHHHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]