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The map label for this gene is cobF [H]

Identifier: 83594300

GI number: 83594300

Start: 3420434

End: 3421207

Strand: Direct

Name: cobF [H]

Synonym: Rru_A2970

Alternate gene names: 83594300

Gene position: 3420434-3421207 (Clockwise)

Preceding gene: 83594299

Following gene: 83594302

Centisome position: 78.58

GC content: 65.89

Gene sequence:

>774_bases
ATGCGTCACGTTTCGATCATCGGCATCGGCCCGGGCGATCCCGACTGCCTGACCTTGCGGGCGGCGCGACGGATCGCCGA
GGTCGATGTCTTCTTTTTTCTCGACAAGGTGGGGCGGGGCAAGGACGAGTTGCTGGCCCTGCGCCGCACCATTCTTGACC
GCCACGCCACCCCCGGCCGCTACCGCGTCGTCACCGTTCCCAGCCCGGTTCGCGATACCAGCGCCTCCTACCGCGACGGG
GTCGAAGACTGGTACGCCGAGCGGCTGGCGATCTTTCGCCGCCTGATCACCGATGAGTTGACCGAAGAGGGCCACGGCGC
CTTTCTGGTCTGGGGCGATCCCGGACTTTATGACGGCACCTTGCAGATCCTCGCCCGCTTAAGCGGCGAAGAGGGCGCGT
CCTTTGACTACGACGTCCTTCCCGGCATCACCGCCGTTCAGGCCCTGGCCGCCCGCCACCGCATCCCGCTCAACCGCATC
GGCGAATCGATCGAGATCACCACCGGCCGCCGCCTGGAGACCGCCGATCCGGCGAGCCTGCACAACAGCGTGGTTCTGCT
TGATGGCAATGCCACCTTCCAGCGCTTCACCCAAACCGATCTGGAGATCTATTGGGGGGCCTATCTCGGCACCCCCGACG
AAATCCTGATCAGCGGCCCGCTGGCCGAAACCTCCGAGGCGATCCTCGCCCGCCGCGAGCGGGCGCGCCAAGCCAAGGGC
TGGATCATGGACACCTATATCCTGCGCAAGCCCGAGGACGAGGCGAAAGGTTAG

Upstream 100 bases:

>100_bases
CCGCTCGCCCTCAAACGCAAGAACATCGGCAAGGGCCGCGAGCGCATCGAAGTGCTGCTGGCTGGGGATTAGCCGCCGGC
CAAAAGGAGACGCTTGCGCC

Downstream 100 bases:

>100_bases
GCGGCGGCGCGACGGAACAGCCGGCCGCGCTCGGTGACCAGCACGCAGACCAGGGCGAGAATGCCAAAGCCGGCGAAGCC
CATCATCAGCGGCCGGACGC

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRHVSIIGIGPGDPDCLTLRAARRIAEVDVFFFLDKVGRGKDELLALRRTILDRHATPGRYRVVTVPSPVRDTSASYRDG
VEDWYAERLAIFRRLITDELTEEGHGAFLVWGDPGLYDGTLQILARLSGEEGASFDYDVLPGITAVQALAARHRIPLNRI
GESIEITTGRRLETADPASLHNSVVLLDGNATFQRFTQTDLEIYWGAYLGTPDEILISGPLAETSEAILARRERARQAKG
WIMDTYILRKPEDEAKG

Sequences:

>Translated_257_residues
MRHVSIIGIGPGDPDCLTLRAARRIAEVDVFFFLDKVGRGKDELLALRRTILDRHATPGRYRVVTVPSPVRDTSASYRDG
VEDWYAERLAIFRRLITDELTEEGHGAFLVWGDPGLYDGTLQILARLSGEEGASFDYDVLPGITAVQALAARHRIPLNRI
GESIEITTGRRLETADPASLHNSVVLLDGNATFQRFTQTDLEIYWGAYLGTPDEILISGPLAETSEAILARRERARQAKG
WIMDTYILRKPEDEAKG
>Mature_257_residues
MRHVSIIGIGPGDPDCLTLRAARRIAEVDVFFFLDKVGRGKDELLALRRTILDRHATPGRYRVVTVPSPVRDTSASYRDG
VEDWYAERLAIFRRLITDELTEEGHGAFLVWGDPGLYDGTLQILARLSGEEGASFDYDVLPGITAVQALAARHRIPLNRI
GESIEITTGRRLETADPASLHNSVVLLDGNATFQRFTQTDLEIYWGAYLGTPDEILISGPLAETSEAILARRERARQAKG
WIMDTYILRKPEDEAKG

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28632; Mature: 28632

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVSIIGIGPGDPDCLTLRAARRIAEVDVFFFLDKVGRGKDELLALRRTILDRHATPGR
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
YRVVTVPSPVRDTSASYRDGVEDWYAERLAIFRRLITDELTEEGHGAFLVWGDPGLYDGT
EEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LQILARLSGEEGASFDYDVLPGITAVQALAARHRIPLNRIGESIEITTGRRLETADPASL
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHCCCEEEECCCCEECCCCCHHH
HNSVVLLDGNATFQRFTQTDLEIYWGAYLGTPDEILISGPLAETSEAILARRERARQAKG
CCCEEEEECCCHHHHHHHCCEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
WIMDTYILRKPEDEAKG
CEEEHEEEECCCHHCCC
>Mature Secondary Structure
MRHVSIIGIGPGDPDCLTLRAARRIAEVDVFFFLDKVGRGKDELLALRRTILDRHATPGR
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
YRVVTVPSPVRDTSASYRDGVEDWYAERLAIFRRLITDELTEEGHGAFLVWGDPGLYDGT
EEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LQILARLSGEEGASFDYDVLPGITAVQALAARHRIPLNRIGESIEITTGRRLETADPASL
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCHHHCCCEEEECCCCEECCCCCHHH
HNSVVLLDGNATFQRFTQTDLEIYWGAYLGTPDEILISGPLAETSEAILARRERARQAKG
CCCEEEEECCCHHHHHHHCCEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
WIMDTYILRKPEDEAKG
CEEEHEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]