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The map label for this gene is pqqL [C]

Identifier: 83594302

GI number: 83594302

Start: 3422648

End: 3424027

Strand: Direct

Name: pqqL [C]

Synonym: Rru_A2972

Alternate gene names: 83594302

Gene position: 3422648-3424027 (Clockwise)

Preceding gene: 83594300

Following gene: 83594303

Centisome position: 78.63

GC content: 67.54

Gene sequence:

>1380_bases
ATGATCAAAAGACGCTTTGGTTTCCGGGGACCGGGCTCACGCCTGGGGGCCCTGATCGTGCTCGTGGTTCTGGGTCTGCC
GGCCCTAGCCCGCGCCCAGGTCTTCAATCCCGAGACCTTCACCTTGCCAAACGGCATGGAGGTGGTGGTGATCCCCAACC
ACCGGGTGCCGGTGGTTCACCACATGGTGTGGTACAAGATCGGCGCCGCCGACGAGCCGGCGGGGAAATCCGGGCTTGCC
CATTTGCTCGAACACTTGATGTTCAAGGGCACGCCGACCATTCCGCCGGGCGAATTCTCCAAGATCGTCGCCCGCAACGG
CGGCCAGGACAACGCCTTCACCAGTTCCGACTTCACCGCCTATTTCCAGTCCATCGCCAAGGACCGCCTGCCGATGGTCA
TGGAGATGGAGGCCGATCGCATGGCCAATCTGCGGCTGAGCGAGGAGGACTTCCAGACCGAGCGCCAGGTGGTGCGCGAG
GAACGGCGCTCGCGCACCGATAACGAACCGGGCGAACTGCTGTCCGAACGCATCGGTCAGGCGCTATGGGGCACCCACCC
CTATAAGAACCCGATCATCGGCTGGGAACCCGAGCTGATGGCCCTGACCCGGGCCGACGCCCTGGCCTTCTATGACCGCT
ATTACGCGCCCAACAACGCCATCTTGGTGGTGGCGGGCGACATCACGGCGGCGGAATTGAAGCCCTTGGCCGAGCGCACC
TATGGCGCCCTGCCCCGGCGCGACACGCCCCAGCGCGCCAGCTTGCGCGATCCCTTGCGCGCCCTGCCGCCGCCGGCCGA
AACCGTCATCACCATGCATCACGCCCAGGTCGCCCAGCCGTCGTTCTCGCGGCGCTATGTGGCGCCCTCGGCCGCCTTCG
ATCCCCAGGGCATGGCCGACGCCCTGGAGGTTCTCGACGAGATCCTCGGCGGCGGCTCCAGCGGCCGGCTGTATAAGCAT
CTGGTCATCGAGCGCGGCATGGCCGTTTCGGCGGGCAGTTGGTATCGCGGCGAGGCCCTGGATTGGGGCAGCTTCGGCCT
GTACGCCAGCCCGCGCGACGGGGTGGCGATGGCCGATCTGGTCGCCGCCGTCGATGCCGAAGTCGCCAGCCTGCTTGATC
AGGGGGTGAAGGCCGACGAGGTCGATGACGCCAAGCGCCGCCTGACCGCCGGTCTGGTCTATGCCCGCGATTCGCTTTCC
GAAGGCGCCCGGGCGCTGGGCGAGGCCCTGACCACCGGCAGTTCCGTGGCCCAGGTCGAATCCTGGCCCGAGCGTATCAA
GGCCGTCACCCCCGAACAGGTGAGCGCCGCCGCCCGCGCCGTGCTTGGCCGGCGCGACCGTTCGGTGACCGGCTTCCTTC
TTCCCGAGCCGCGGAGTTGA

Upstream 100 bases:

>100_bases
GGGGGCGGCCGGCGGATCGCCGGCAGGCGGCCCCATTGTGGCCGTGATCGCGGTGTCCCATATCGGCGCCGTCGCGGCCG
CAAGAAAGAGATTTTGACCG

Downstream 100 bases:

>100_bases
TCGCGATGAAGCGCCTGCTGTTTGCCCTTGTTCTGCTCGTCGCGCCCTGGGGGGCCTTCTCCGCCCAGGCCACGCCGGTT
CAGACCGTCACCACCCCCTC

Product: peptidase M16-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MIKRRFGFRGPGSRLGALIVLVVLGLPALARAQVFNPETFTLPNGMEVVVIPNHRVPVVHHMVWYKIGAADEPAGKSGLA
HLLEHLMFKGTPTIPPGEFSKIVARNGGQDNAFTSSDFTAYFQSIAKDRLPMVMEMEADRMANLRLSEEDFQTERQVVRE
ERRSRTDNEPGELLSERIGQALWGTHPYKNPIIGWEPELMALTRADALAFYDRYYAPNNAILVVAGDITAAELKPLAERT
YGALPRRDTPQRASLRDPLRALPPPAETVITMHHAQVAQPSFSRRYVAPSAAFDPQGMADALEVLDEILGGGSSGRLYKH
LVIERGMAVSAGSWYRGEALDWGSFGLYASPRDGVAMADLVAAVDAEVASLLDQGVKADEVDDAKRRLTAGLVYARDSLS
EGARALGEALTTGSSVAQVESWPERIKAVTPEQVSAAARAVLGRRDRSVTGFLLPEPRS

Sequences:

>Translated_459_residues
MIKRRFGFRGPGSRLGALIVLVVLGLPALARAQVFNPETFTLPNGMEVVVIPNHRVPVVHHMVWYKIGAADEPAGKSGLA
HLLEHLMFKGTPTIPPGEFSKIVARNGGQDNAFTSSDFTAYFQSIAKDRLPMVMEMEADRMANLRLSEEDFQTERQVVRE
ERRSRTDNEPGELLSERIGQALWGTHPYKNPIIGWEPELMALTRADALAFYDRYYAPNNAILVVAGDITAAELKPLAERT
YGALPRRDTPQRASLRDPLRALPPPAETVITMHHAQVAQPSFSRRYVAPSAAFDPQGMADALEVLDEILGGGSSGRLYKH
LVIERGMAVSAGSWYRGEALDWGSFGLYASPRDGVAMADLVAAVDAEVASLLDQGVKADEVDDAKRRLTAGLVYARDSLS
EGARALGEALTTGSSVAQVESWPERIKAVTPEQVSAAARAVLGRRDRSVTGFLLPEPRS
>Mature_459_residues
MIKRRFGFRGPGSRLGALIVLVVLGLPALARAQVFNPETFTLPNGMEVVVIPNHRVPVVHHMVWYKIGAADEPAGKSGLA
HLLEHLMFKGTPTIPPGEFSKIVARNGGQDNAFTSSDFTAYFQSIAKDRLPMVMEMEADRMANLRLSEEDFQTERQVVRE
ERRSRTDNEPGELLSERIGQALWGTHPYKNPIIGWEPELMALTRADALAFYDRYYAPNNAILVVAGDITAAELKPLAERT
YGALPRRDTPQRASLRDPLRALPPPAETVITMHHAQVAQPSFSRRYVAPSAAFDPQGMADALEVLDEILGGGSSGRLYKH
LVIERGMAVSAGSWYRGEALDWGSFGLYASPRDGVAMADLVAAVDAEVASLLDQGVKADEVDDAKRRLTAGLVYARDSLS
EGARALGEALTTGSSVAQVESWPERIKAVTPEQVSAAARAVLGRRDRSVTGFLLPEPRS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=220, Percent_Identity=28.6363636363636, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI94538354, Length=389, Percent_Identity=23.6503856041131, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787770, Length=405, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367164, Length=372, Percent_Identity=22.8494623655914, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=218, Percent_Identity=26.605504587156, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=221, Percent_Identity=24.4343891402715, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323421, Length=339, Percent_Identity=23.598820058997, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357875, Length=195, Percent_Identity=27.1794871794872, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646943, Length=195, Percent_Identity=27.1794871794872, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 50090; Mature: 50090

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRRFGFRGPGSRLGALIVLVVLGLPALARAQVFNPETFTLPNGMEVVVIPNHRVPVVH
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHH
HMVWYKIGAADEPAGKSGLAHLLEHLMFKGTPTIPPGEFSKIVARNGGQDNAFTSSDFTA
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
YFQSIAKDRLPMVMEMEADRMANLRLSEEDFQTERQVVREERRSRTDNEPGELLSERIGQ
HHHHHHHHCCCEEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALWGTHPYKNPIIGWEPELMALTRADALAFYDRYYAPNNAILVVAGDITAAELKPLAERT
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
YGALPRRDTPQRASLRDPLRALPPPAETVITMHHAQVAQPSFSRRYVAPSAAFDPQGMAD
HCCCCCCCCCCCCHHHCHHHHCCCCHHHEEEEHHHHHCCCCCCCCEECCCCCCCCCCHHH
ALEVLDEILGGGSSGRLYKHLVIERGMAVSAGSWYRGEALDWGSFGLYASPRDGVAMADL
HHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VAAVDAEVASLLDQGVKADEVDDAKRRLTAGLVYARDSLSEGARALGEALTTGSSVAQVE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SWPERIKAVTPEQVSAAARAVLGRRDRSVTGFLLPEPRS
HHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MIKRRFGFRGPGSRLGALIVLVVLGLPALARAQVFNPETFTLPNGMEVVVIPNHRVPVVH
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHH
HMVWYKIGAADEPAGKSGLAHLLEHLMFKGTPTIPPGEFSKIVARNGGQDNAFTSSDFTA
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
YFQSIAKDRLPMVMEMEADRMANLRLSEEDFQTERQVVREERRSRTDNEPGELLSERIGQ
HHHHHHHHCCCEEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALWGTHPYKNPIIGWEPELMALTRADALAFYDRYYAPNNAILVVAGDITAAELKPLAERT
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
YGALPRRDTPQRASLRDPLRALPPPAETVITMHHAQVAQPSFSRRYVAPSAAFDPQGMAD
HCCCCCCCCCCCCHHHCHHHHCCCCHHHEEEEHHHHHCCCCCCCCEECCCCCCCCCCHHH
ALEVLDEILGGGSSGRLYKHLVIERGMAVSAGSWYRGEALDWGSFGLYASPRDGVAMADL
HHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VAAVDAEVASLLDQGVKADEVDDAKRRLTAGLVYARDSLSEGARALGEALTTGSSVAQVE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SWPERIKAVTPEQVSAAARAVLGRRDRSVTGFLLPEPRS
HHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]