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The map label for this gene is yhdN [H]

Identifier: 83594208

GI number: 83594208

Start: 3312945

End: 3313940

Strand: Direct

Name: yhdN [H]

Synonym: Rru_A2876

Alternate gene names: 83594208

Gene position: 3312945-3313940 (Clockwise)

Preceding gene: 83594206

Following gene: 83594209

Centisome position: 76.11

GC content: 65.46

Gene sequence:

>996_bases
ATGCGACACCATCGTCTTGGAACCACCGGCCCCCATGTTTCAGCGCTTGGCCTTGGCTGCATGGGCATGTCGGACCTTTA
TGGCCCCTCCGATCGCCAAGAAAGCATCGCGACCATTCATGCCGCCCTCGAGGCCGGGGTCACCGTGCTTGATACGGGCG
ACTTCTATGGCATGGGCCATAACGAGATGCTGATCGCCGAGGCGATCAAGGGCCGCCCGCGTGACGGTTTCCAGGTGAGC
GTCAAGTTTGGCGCCCTGCGCGGACCGGCTGGCGATTGGCTGGGCTATGACGGCCGCCCCCAGGCGGTGAAAAATTTTCT
GGCCTACACCCTTCGGCGGCTCGGCCTTGACCACATCGACATCTATCGCCCGGCCCGCCTTGATCCGGCCGTGCCGATCG
AAGAGACGGTCGGCGCCATCGCCGATCTGGTGACGGCGGGCTATGTCGGGCATATCGGCCTGTCCGAGGTGGGGACGGAC
ACCATCGCCCGCGCCGCCGCCGTCCATCCGATTTGTGATCTGCAGATCGAATACTCGCTGATCTCGCGCGGCATCGAAGA
GGCCATCTTGCCGCGCTGCCGCGAGTTGGGCATCGCCATCACCGCCTATGGCGTGTTGTCGCGGGGATTGATCAGCGGCC
ATTGGCAAGCCGGAAGCACCGATCCGTCGGATTTTCGCAGCCGCAGCCCGCGCTTCCAGCAAGGCAACATCGAACACAAC
CTCGCCCTGGTCGAGGCCCTGGCGGTCATCGCCCGGCGGAAATCCGTCAGCGTCGCCCAAATCGCCATCGCCTGGGTGGC
GGCCCAAGGCGAGGATATCGTGCCTTTGGTCGGCGCCCGCCGCCGTGATCGTCTGAGCGAAGCCTTGGGCGCCCTGGAGG
TGTCGCTTGATGCCGGGGATCTGGCCGCCATCGAAGCCGCCGTTCCCAAAGGCGCCGCCGCCGGCGAGCGCTATAACGCG
CCGCAGATGGCCCATCTCGACAGCGAGCGGCCATAA

Upstream 100 bases:

>100_bases
AAGGCCGATTATCGCACAGCGTCCCGCCCGCCATACTTCCTTTCCGCCAGACCGCGGCCACAGGCCCCCCCACCCCGCCC
CCAGGCAAGGATATCAGGCA

Downstream 100 bases:

>100_bases
AAAAAGACGGGACGCCCCAGTGTTTGAGGACGTCCCGTCCAATGATGCCTCTCCGATCGCGGAAGTCTCGGCTGGCGGCG
GGGAAGTGCGGTTCAGACCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRHHRLGTTGPHVSALGLGCMGMSDLYGPSDRQESIATIHAALEAGVTVLDTGDFYGMGHNEMLIAEAIKGRPRDGFQVS
VKFGALRGPAGDWLGYDGRPQAVKNFLAYTLRRLGLDHIDIYRPARLDPAVPIEETVGAIADLVTAGYVGHIGLSEVGTD
TIARAAAVHPICDLQIEYSLISRGIEEAILPRCRELGIAITAYGVLSRGLISGHWQAGSTDPSDFRSRSPRFQQGNIEHN
LALVEALAVIARRKSVSVAQIAIAWVAAQGEDIVPLVGARRRDRLSEALGALEVSLDAGDLAAIEAAVPKGAAAGERYNA
PQMAHLDSERP

Sequences:

>Translated_331_residues
MRHHRLGTTGPHVSALGLGCMGMSDLYGPSDRQESIATIHAALEAGVTVLDTGDFYGMGHNEMLIAEAIKGRPRDGFQVS
VKFGALRGPAGDWLGYDGRPQAVKNFLAYTLRRLGLDHIDIYRPARLDPAVPIEETVGAIADLVTAGYVGHIGLSEVGTD
TIARAAAVHPICDLQIEYSLISRGIEEAILPRCRELGIAITAYGVLSRGLISGHWQAGSTDPSDFRSRSPRFQQGNIEHN
LALVEALAVIARRKSVSVAQIAIAWVAAQGEDIVPLVGARRRDRLSEALGALEVSLDAGDLAAIEAAVPKGAAAGERYNA
PQMAHLDSERP
>Mature_331_residues
MRHHRLGTTGPHVSALGLGCMGMSDLYGPSDRQESIATIHAALEAGVTVLDTGDFYGMGHNEMLIAEAIKGRPRDGFQVS
VKFGALRGPAGDWLGYDGRPQAVKNFLAYTLRRLGLDHIDIYRPARLDPAVPIEETVGAIADLVTAGYVGHIGLSEVGTD
TIARAAAVHPICDLQIEYSLISRGIEEAILPRCRELGIAITAYGVLSRGLISGHWQAGSTDPSDFRSRSPRFQQGNIEHN
LALVEALAVIARRKSVSVAQIAIAWVAAQGEDIVPLVGARRRDRLSEALGALEVSLDAGDLAAIEAAVPKGAAAGERYNA
PQMAHLDSERP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=27.831715210356, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=27.6872964169381, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27436966, Length=319, Percent_Identity=26.6457680250784, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436964, Length=319, Percent_Identity=26.3322884012539, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI27436962, Length=319, Percent_Identity=26.3322884012539, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=28.3870967741935, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI223718702, Length=293, Percent_Identity=25.938566552901, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=25.2669039145907, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=30.2547770700637, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=28.2608695652174, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=25.748502994012, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=305, Percent_Identity=25.5737704918033, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=26.6106442577031, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787674, Length=207, Percent_Identity=32.3671497584541, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325384, Length=340, Percent_Identity=25.5882352941176, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=26.0726072607261, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=26.625386996904, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=25, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=323, Percent_Identity=25.077399380805, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24646159, Length=304, Percent_Identity=24.6710526315789, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35262; Mature: 35262

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHHRLGTTGPHVSALGLGCMGMSDLYGPSDRQESIATIHAALEAGVTVLDTGDFYGMGH
CCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NEMLIAEAIKGRPRDGFQVSVKFGALRGPAGDWLGYDGRPQAVKNFLAYTLRRLGLDHID
CCCHHHHHHCCCCCCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IYRPARLDPAVPIEETVGAIADLVTAGYVGHIGLSEVGTDTIARAAAVHPICDLQIEYSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCHHCCEEEHHH
ISRGIEEAILPRCRELGIAITAYGVLSRGLISGHWQAGSTDPSDFRSRSPRFQQGNIEHN
HHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHH
LALVEALAVIARRKSVSVAQIAIAWVAAQGEDIVPLVGARRRDRLSEALGALEVSLDAGD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHEEEEECCCC
LAAIEAAVPKGAAAGERYNAPQMAHLDSERP
HHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MRHHRLGTTGPHVSALGLGCMGMSDLYGPSDRQESIATIHAALEAGVTVLDTGDFYGMGH
CCCCCCCCCCCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCC
NEMLIAEAIKGRPRDGFQVSVKFGALRGPAGDWLGYDGRPQAVKNFLAYTLRRLGLDHID
CCCHHHHHHCCCCCCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IYRPARLDPAVPIEETVGAIADLVTAGYVGHIGLSEVGTDTIARAAAVHPICDLQIEYSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCHHCCEEEHHH
ISRGIEEAILPRCRELGIAITAYGVLSRGLISGHWQAGSTDPSDFRSRSPRFQQGNIEHN
HHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHH
LALVEALAVIARRKSVSVAQIAIAWVAAQGEDIVPLVGARRRDRLSEALGALEVSLDAGD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHEEEEECCCC
LAAIEAAVPKGAAAGERYNAPQMAHLDSERP
HHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]