Click here to switch to the map view.

The map label for this gene is tdcB [H]

Identifier: 83594209

GI number: 83594209

Start: 3314712

End: 3315980

Strand: Direct

Name: tdcB [H]

Synonym: Rru_A2877

Alternate gene names: 83594209

Gene position: 3314712-3315980 (Clockwise)

Preceding gene: 83594208

Following gene: 83594210

Centisome position: 76.15

GC content: 67.22

Gene sequence:

>1269_bases
ATGTCGCCCTTCCCCCCGTTTCCGGCCGCTTCGGCCGTCCCCGCCGTCACCCTGGCCGATGTGGAAGCCGCGGCCCGGCT
GATCGCCCATGCCGTGCCCCATACCCCGCTGCTCCCCTCGCGCACCCTGTCGCGGCTGACCGGGGCCGAGGTTTTCATCA
AATTCGAGAACCACCAGTTCACCGCCTCGTTCAAGGAGCGCGGCGCGCTCAACCGGTTGAGCGCGCTGAGCGAGACCGAG
CGGGCGCGCGGCGTCATCGCCATGAGCGCGGGCAATCACGCCCAGGGCGTGGCCTATCACGCCCAGCGCCTGGGCATTCC
CGCCGTTATCGTCATGCCCGCTGACACGCCCTTCGTAAAGGTCAAGCACACCCGTGATTTCGGCGCCCGCGTGGTGCTGG
AAGGCGAGACCGTGGCCGAATCGCGGCTGGTGGCCGAGCGCATCCGCGAGGAGGAGGGACTGACCTTCGTTCATCCCTAT
AATGATCCCTGGGTGATCGCCGGCCAGGGGACGGTGGCCTTGGAAATGCTTGCCGATCAGCCCGACCTCGACATCCTGGT
CGCCCCGATCGGCGGCGGCGGCCTGCTGGGCGGCATGGCGGTGGCGGCCAAGGCGGTCAAACCGGCCATTGAGATGATCG
GCGTTCAGGTCGGGCTTTATCCTTCGGCCTATAACGCCCTCCACGGCCTGCCGCCTTGCACCGGCGGCGCCACGGTGGCC
GAGGGCATCGCCGTCAAGGAACCGGGCGATCTGACCTTGCCGCTGCTGCGCGCTTTGGTCTCGCGCATCATCCTGGTCGA
TGAGACGGCGGTCGAGGAAGCCATCTCGCTCTATCTCTCGGTCGAAAAGACCGTGGCCGAGGGGGCGGGGGCGGCGTCGC
TCGCCGCCCTGTTGACCGAGCCCCAGCGCTTTCGCGGCAAAAAGGTCGGTCTGGTGCTGAGCGGCGGCAATATCGATCCG
CGGATCATGGCCTCGGTCATCATGCGCAGCCTTGTGCGCGAGGGCCGAATCGCCCATCTCTCGATCAGGATCGGCGACAA
GCCGGGGCAACTCGCCCGGGTGGCGACGGTGATCGGCGAAACCGGCGGCAATATCGTCGAGGTCCGCCATGAACGCCTGA
CCTCGGATATTTCGGTCAAATCCACCGATCTGCGGGTGATCCTGGAGACCCGCGACCATACCCATCTGGCCGAGATCCTT
GAACGCCTCGCCGCCGCCGGTTTTCCGGCCAACGAACGCTCGTTCAGCGGCCCGGCCGCCGGCGATTAA

Upstream 100 bases:

>100_bases
TCACACGGCGGGCCGTAGCGGAGATCGCCAACGGGGGCTTGCCCCACCCGGCGGCTGGGTTTAGGCAAAGACCCATGTTC
GCCCCAGGAGTCTTCCCCCG

Downstream 100 bases:

>100_bases
GCCTCTCGCCGATGGCCGGGGGGCGCGGCCCTCCGGCCATCGGGCGGCTTGCCGGGAAGAACGCGAAAGGGACGCCGATG
AGACCTCCGCTTGGATCCTT

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSPFPPFPAASAVPAVTLADVEAAARLIAHAVPHTPLLPSRTLSRLTGAEVFIKFENHQFTASFKERGALNRLSALSETE
RARGVIAMSAGNHAQGVAYHAQRLGIPAVIVMPADTPFVKVKHTRDFGARVVLEGETVAESRLVAERIREEEGLTFVHPY
NDPWVIAGQGTVALEMLADQPDLDILVAPIGGGGLLGGMAVAAKAVKPAIEMIGVQVGLYPSAYNALHGLPPCTGGATVA
EGIAVKEPGDLTLPLLRALVSRIILVDETAVEEAISLYLSVEKTVAEGAGAASLAALLTEPQRFRGKKVGLVLSGGNIDP
RIMASVIMRSLVREGRIAHLSIRIGDKPGQLARVATVIGETGGNIVEVRHERLTSDISVKSTDLRVILETRDHTHLAEIL
ERLAAAGFPANERSFSGPAAGD

Sequences:

>Translated_422_residues
MSPFPPFPAASAVPAVTLADVEAAARLIAHAVPHTPLLPSRTLSRLTGAEVFIKFENHQFTASFKERGALNRLSALSETE
RARGVIAMSAGNHAQGVAYHAQRLGIPAVIVMPADTPFVKVKHTRDFGARVVLEGETVAESRLVAERIREEEGLTFVHPY
NDPWVIAGQGTVALEMLADQPDLDILVAPIGGGGLLGGMAVAAKAVKPAIEMIGVQVGLYPSAYNALHGLPPCTGGATVA
EGIAVKEPGDLTLPLLRALVSRIILVDETAVEEAISLYLSVEKTVAEGAGAASLAALLTEPQRFRGKKVGLVLSGGNIDP
RIMASVIMRSLVREGRIAHLSIRIGDKPGQLARVATVIGETGGNIVEVRHERLTSDISVKSTDLRVILETRDHTHLAEIL
ERLAAAGFPANERSFSGPAAGD
>Mature_421_residues
SPFPPFPAASAVPAVTLADVEAAARLIAHAVPHTPLLPSRTLSRLTGAEVFIKFENHQFTASFKERGALNRLSALSETER
ARGVIAMSAGNHAQGVAYHAQRLGIPAVIVMPADTPFVKVKHTRDFGARVVLEGETVAESRLVAERIREEEGLTFVHPYN
DPWVIAGQGTVALEMLADQPDLDILVAPIGGGGLLGGMAVAAKAVKPAIEMIGVQVGLYPSAYNALHGLPPCTGGATVAE
GIAVKEPGDLTLPLLRALVSRIILVDETAVEEAISLYLSVEKTVAEGAGAASLAALLTEPQRFRGKKVGLVLSGGNIDPR
IMASVIMRSLVREGRIAHLSIRIGDKPGQLARVATVIGETGGNIVEVRHERLTSDISVKSTDLRVILETRDHTHLAEILE
RLAAAGFPANERSFSGPAAGD

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=317, Percent_Identity=38.1703470031546, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI19923959, Length=144, Percent_Identity=35.4166666666667, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33469958, Length=275, Percent_Identity=28.3636363636364, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789505, Length=310, Percent_Identity=42.258064516129, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1790207, Length=380, Percent_Identity=35, Blast_Score=173, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71991565, Length=400, Percent_Identity=38, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17537387, Length=399, Percent_Identity=34.3358395989975, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17508781, Length=310, Percent_Identity=30.9677419354839, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322631, Length=319, Percent_Identity=36.9905956112853, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320930, Length=401, Percent_Identity=30.9226932668329, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6319788, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355833, Length=401, Percent_Identity=36.6583541147132, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24645328, Length=295, Percent_Identity=33.2203389830508, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 44478; Mature: 44347

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFPPFPAASAVPAVTLADVEAAARLIAHAVPHTPLLPSRTLSRLTGAEVFIKFENHQF
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEEECCEE
TASFKERGALNRLSALSETERARGVIAMSAGNHAQGVAYHAQRLGIPAVIVMPADTPFVK
EECHHHCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCEEE
VKHTRDFGARVVLEGETVAESRLVAERIREEEGLTFVHPYNDPWVIAGQGTVALEMLADQ
EEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCEEEEEECCC
PDLDILVAPIGGGGLLGGMAVAAKAVKPAIEMIGVQVGLYPSAYNALHGLPPCTGGATVA
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCCHHH
EGIAVKEPGDLTLPLLRALVSRIILVDETAVEEAISLYLSVEKTVAEGAGAASLAALLTE
CCEEECCCCCCCHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PQRFRGKKVGLVLSGGNIDPRIMASVIMRSLVREGRIAHLSIRIGDKPGQLARVATVIGE
HHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHC
TGGNIVEVRHERLTSDISVKSTDLRVILETRDHTHLAEILERLAAAGFPANERSFSGPAA
CCCCEEEEEHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
GD
CC
>Mature Secondary Structure 
SPFPPFPAASAVPAVTLADVEAAARLIAHAVPHTPLLPSRTLSRLTGAEVFIKFENHQF
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEEEECCEE
TASFKERGALNRLSALSETERARGVIAMSAGNHAQGVAYHAQRLGIPAVIVMPADTPFVK
EECHHHCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCEEE
VKHTRDFGARVVLEGETVAESRLVAERIREEEGLTFVHPYNDPWVIAGQGTVALEMLADQ
EEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCEEEEEECCC
PDLDILVAPIGGGGLLGGMAVAAKAVKPAIEMIGVQVGLYPSAYNALHGLPPCTGGATVA
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHCCCCCCCCCCHHH
EGIAVKEPGDLTLPLLRALVSRIILVDETAVEEAISLYLSVEKTVAEGAGAASLAALLTE
CCEEECCCCCCCHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PQRFRGKKVGLVLSGGNIDPRIMASVIMRSLVREGRIAHLSIRIGDKPGQLARVATVIGE
HHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHC
TGGNIVEVRHERLTSDISVKSTDLRVILETRDHTHLAEILERLAAAGFPANERSFSGPAA
CCCCEEEEEHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
GD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA