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The map label for this gene is thyX [H]

Identifier: 83594124

GI number: 83594124

Start: 3226427

End: 3227284

Strand: Direct

Name: thyX [H]

Synonym: Rru_A2792

Alternate gene names: 83594124

Gene position: 3226427-3227284 (Clockwise)

Preceding gene: 83594123

Following gene: 83594125

Centisome position: 74.12

GC content: 67.48

Gene sequence:

>858_bases
ATGACCGAACTGCTTTTCGCCCCCACCGCCACGGTGGTGGCCCACTCATCGATGGACCCCGCCGGCCTTGCCGGGTGGGC
GGCCGAAATGGGCTATGGCGCCCTGATCGACGACGCGACGACGCCGCTGGGCGATATCGCCCAGGCGTCGACCGGCGCCG
GATCGGCCGATGTCCTGCCCGAATTCGCCGGGCGCTTCTGCTACCGCTCGTTCAAGAAGGGCCGGCCGGCCGACGAATAC
GTCGCCCATATCCTCGACTCGGGCCATGGCTCGGTGCTCGAACATGTCAGCGTGTCCTTCGCCGTCACCGGCGTCTCGCG
CGCCCTGACCCACGAGTTGATCCGCCACCGCGCCGGCACGGCGGTCAGCCAGGAAAGCCAGCGCTACGTCGATGCCAAAT
CGGTGAATTTCGTCGTGCCGCCGTTGCTGGTGGCCGAGATCGACCGCCTGAAAGCCAGCGGCGCGGCCGGCGAAGCCGAC
GCCCTGTGCGCCGAATTCCTGACCGATTGCGAAAGCGCCCTTGGCCGTTACAAGCGCTGGCAGGAGTCGTTCCGCGCCCA
GGTCGAGGCTTTGGGCGTCAGCGAACCGACCCTGATCAAGAAGCGCGCCAATGAGGCCGCCCGCTGCATCCTGCCCAACG
CCACCGAAACCCGGCTGGTGTGGACGATGAACCTGCGCTCGGCCCGCCATGTGGTGGAACTGCGCGGCCATCGCGACGCC
GATCTGGAGATCCGCCGCCTGTCGTGCCTGCTGGCGCGCAAGATGAAAGAGGTCGCGCCGCTGGTCTTCGCCGATGTCGG
GGTGTTCACCGACAGCGACGGCTTCGAAAGCGTCGGCGTCGGCCACCACAAGGTTTAA

Upstream 100 bases:

>100_bases
TTTTGGCTCGACCGGCGTGTCGGTGGCCGAAACGCCGCGCGGCTAATCGTCGCCGCCGCACGATGACCCGATATCAGATC
ACCCGACCAACGAGGACGGC

Downstream 100 bases:

>100_bases
GCGCCGATGGGGCCGCGCGCGCTCTCGGCCCTGGAAGCCCGCCGCATCGCCTTGCGGGCCCAGGGCTTCGGCCGCGCCCG
GCCCCCTACGCCAAGCCCCC

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTELLFAPTATVVAHSSMDPAGLAGWAAEMGYGALIDDATTPLGDIAQASTGAGSADVLPEFAGRFCYRSFKKGRPADEY
VAHILDSGHGSVLEHVSVSFAVTGVSRALTHELIRHRAGTAVSQESQRYVDAKSVNFVVPPLLVAEIDRLKASGAAGEAD
ALCAEFLTDCESALGRYKRWQESFRAQVEALGVSEPTLIKKRANEAARCILPNATETRLVWTMNLRSARHVVELRGHRDA
DLEIRRLSCLLARKMKEVAPLVFADVGVFTDSDGFESVGVGHHKV

Sequences:

>Translated_285_residues
MTELLFAPTATVVAHSSMDPAGLAGWAAEMGYGALIDDATTPLGDIAQASTGAGSADVLPEFAGRFCYRSFKKGRPADEY
VAHILDSGHGSVLEHVSVSFAVTGVSRALTHELIRHRAGTAVSQESQRYVDAKSVNFVVPPLLVAEIDRLKASGAAGEAD
ALCAEFLTDCESALGRYKRWQESFRAQVEALGVSEPTLIKKRANEAARCILPNATETRLVWTMNLRSARHVVELRGHRDA
DLEIRRLSCLLARKMKEVAPLVFADVGVFTDSDGFESVGVGHHKV
>Mature_284_residues
TELLFAPTATVVAHSSMDPAGLAGWAAEMGYGALIDDATTPLGDIAQASTGAGSADVLPEFAGRFCYRSFKKGRPADEYV
AHILDSGHGSVLEHVSVSFAVTGVSRALTHELIRHRAGTAVSQESQRYVDAKSVNFVVPPLLVAEIDRLKASGAAGEADA
LCAEFLTDCESALGRYKRWQESFRAQVEALGVSEPTLIKKRANEAARCILPNATETRLVWTMNLRSARHVVELRGHRDAD
LEIRRLSCLLARKMKEVAPLVFADVGVFTDSDGFESVGVGHHKV

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 30689; Mature: 30558

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELLFAPTATVVAHSSMDPAGLAGWAAEMGYGALIDDATTPLGDIAQASTGAGSADVLP
CCCEEECCCHHHHEECCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHCCCCCCCHHHHH
EFAGRFCYRSFKKGRPADEYVAHILDSGHGSVLEHVSVSFAVTGVSRALTHELIRHRAGT
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AVSQESQRYVDAKSVNFVVPPLLVAEIDRLKASGAAGEADALCAEFLTDCESALGRYKRW
HHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QESFRAQVEALGVSEPTLIKKRANEAARCILPNATETRLVWTMNLRSARHVVELRGHRDA
HHHHHHHHHHCCCCCCHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCC
DLEIRRLSCLLARKMKEVAPLVFADVGVFTDSDGFESVGVGHHKV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TELLFAPTATVVAHSSMDPAGLAGWAAEMGYGALIDDATTPLGDIAQASTGAGSADVLP
CCEEECCCHHHHEECCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHCCCCCCCHHHHH
EFAGRFCYRSFKKGRPADEYVAHILDSGHGSVLEHVSVSFAVTGVSRALTHELIRHRAGT
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AVSQESQRYVDAKSVNFVVPPLLVAEIDRLKASGAAGEADALCAEFLTDCESALGRYKRW
HHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QESFRAQVEALGVSEPTLIKKRANEAARCILPNATETRLVWTMNLRSARHVVELRGHRDA
HHHHHHHHHHCCCCCCHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCC
DLEIRRLSCLLARKMKEVAPLVFADVGVFTDSDGFESVGVGHHKV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA