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The map label for this gene is fabI1 [H]

Identifier: 83593956

GI number: 83593956

Start: 3053268

End: 3054107

Strand: Reverse

Name: fabI1 [H]

Synonym: Rru_A2624

Alternate gene names: 83593956

Gene position: 3054107-3053268 (Counterclockwise)

Preceding gene: 83593958

Following gene: 83593955

Centisome position: 70.16

GC content: 61.31

Gene sequence:

>840_bases
ATGCCGAATTCCACCGCGCTTCTTGCCGGCAAGAAGGGCCTCGTTCTCGGTGTCGCCAACGATCGGTCGATCGCCTGGGG
TATCGCCAAGGCCGCCAGCGACGCGGGGGCCAGCATCGCCTTCACCTATCAGGGGGACCCCTTGCTCAAGCGGGTGAAGC
CTCTGGTCGAGGGGTTGAGCGAGCGTCATCTTCTGATGCCCTGCGATGTGACCGATGAAGCCAGCCTGGACGCGGTGTTC
GCCACGCTGAAGGAAACCTGGGGCACCATCGATTTCGTCGTTCACGCCGTGGCCTTTTCCGATAAGGATCAGCTCAAGGG
CCACTATATGCATACGACGCGCGAGAACTTTCAGCAGACCATGCTGATTTCGGTGTTCTCGTTCACCGATATCGCCCGTC
GCGCCTCGGAAATCATGAATGACGGCGGCGCGATGATCACGCTGACCTATTACGGCGCCGAACGCGTGATGCCCCATTAC
AATGTCATGGGCGTGGCCAAGGCGGCGCTGGAAGCCAGCGTGCGCTATCTGGCCGCCGACCTGGGCGGGCGCGGCATCCG
CGTCAACGCCATTTCGGCCGGACCGATCAAGACCCTGGCCGCCTCGGGCATCGGCGATTTCCGCTATATCCTGAAGTGGA
ACGAGTATAACAGCCCGCTGCGCCGCAATGTGACCATCGACGAGGTTGGCAATTCGGGCTTGTATCTGCTGTCGGATCTG
TCGCGCGGCGTGACCGGCGAGGTCCATCACGTGGATAGCGGCTATCATCTGGTGGGCATGCTGAACATGGACAGCGTCAG
CGAGGTTTCCGCCCTGCTCGCCACCGTCAAGAAGGATTAA

Upstream 100 bases:

>100_bases
TAGGATGCCGCCCTTCCGTCCTCTAAGGACGGGATTCAACCGATTTTCACCGGCCCTCAGACGGGCCGGTCTTATTACCA
ATACCATAAAGGGGACTCCC

Downstream 100 bases:

>100_bases
GCCCCCATGGCCGGCGACAGCTTCGGAACGCTCTTCCGCTTCACCAGCTTTGGTGAAAGCCACGGGCCGGCCATCGGTTG
CGTGGTCGAAGGGGTGCCAC

Product: enoyl-[acyl-carrier-protein] reductase [NADH]

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 1 [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MPNSTALLAGKKGLVLGVANDRSIAWGIAKAASDAGASIAFTYQGDPLLKRVKPLVEGLSERHLLMPCDVTDEASLDAVF
ATLKETWGTIDFVVHAVAFSDKDQLKGHYMHTTRENFQQTMLISVFSFTDIARRASEIMNDGGAMITLTYYGAERVMPHY
NVMGVAKAALEASVRYLAADLGGRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNSPLRRNVTIDEVGNSGLYLLSDL
SRGVTGEVHHVDSGYHLVGMLNMDSVSEVSALLATVKKD

Sequences:

>Translated_279_residues
MPNSTALLAGKKGLVLGVANDRSIAWGIAKAASDAGASIAFTYQGDPLLKRVKPLVEGLSERHLLMPCDVTDEASLDAVF
ATLKETWGTIDFVVHAVAFSDKDQLKGHYMHTTRENFQQTMLISVFSFTDIARRASEIMNDGGAMITLTYYGAERVMPHY
NVMGVAKAALEASVRYLAADLGGRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNSPLRRNVTIDEVGNSGLYLLSDL
SRGVTGEVHHVDSGYHLVGMLNMDSVSEVSALLATVKKD
>Mature_278_residues
PNSTALLAGKKGLVLGVANDRSIAWGIAKAASDAGASIAFTYQGDPLLKRVKPLVEGLSERHLLMPCDVTDEASLDAVFA
TLKETWGTIDFVVHAVAFSDKDQLKGHYMHTTRENFQQTMLISVFSFTDIARRASEIMNDGGAMITLTYYGAERVMPHYN
VMGVAKAALEASVRYLAADLGGRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNSPLRRNVTIDEVGNSGLYLLSDLS
RGVTGEVHHVDSGYHLVGMLNMDSVSEVSALLATVKKD

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=259, Percent_Identity=49.8069498069498, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=30.1158301158301, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=26.8482490272374, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 30141; Mature: 30010

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSTALLAGKKGLVLGVANDRSIAWGIAKAASDAGASIAFTYQGDPLLKRVKPLVEGLS
CCCCCEEEECCCEEEEEECCCCCEEHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCC
ERHLLMPCDVTDEASLDAVFATLKETWGTIDFVVHAVAFSDKDQLKGHYMHTTRENFQQT
CCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCEEEHHHHHHHHHH
MLISVFSFTDIARRASEIMNDGGAMITLTYYGAERVMPHYNVMGVAKAALEASVRYLAAD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LGGRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNSPLRRNVTIDEVGNSGLYLLSDL
CCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCHHCCCCHHHCCCCCEEEEEHH
SRGVTGEVHHVDSGYHLVGMLNMDSVSEVSALLATVKKD
CCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNSTALLAGKKGLVLGVANDRSIAWGIAKAASDAGASIAFTYQGDPLLKRVKPLVEGLS
CCCCEEEECCCEEEEEECCCCCEEHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCC
ERHLLMPCDVTDEASLDAVFATLKETWGTIDFVVHAVAFSDKDQLKGHYMHTTRENFQQT
CCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCEEEHHHHHHHHHH
MLISVFSFTDIARRASEIMNDGGAMITLTYYGAERVMPHYNVMGVAKAALEASVRYLAAD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LGGRGIRVNAISAGPIKTLAASGIGDFRYILKWNEYNSPLRRNVTIDEVGNSGLYLLSDL
CCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCHHCCCCHHHCCCCCEEEEEHH
SRGVTGEVHHVDSGYHLVGMLNMDSVSEVSALLATVKKD
CCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]