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The map label for this gene is aroC

Identifier: 83593955

GI number: 83593955

Start: 3052161

End: 3053261

Strand: Reverse

Name: aroC

Synonym: Rru_A2623

Alternate gene names: 83593955

Gene position: 3053261-3052161 (Counterclockwise)

Preceding gene: 83593956

Following gene: 83593953

Centisome position: 70.14

GC content: 67.21

Gene sequence:

>1101_bases
ATGGCCGGCGACAGCTTCGGAACGCTCTTCCGCTTCACCAGCTTTGGTGAAAGCCACGGGCCGGCCATCGGTTGCGTGGT
CGAAGGGGTGCCACCGGGCATTCCCTTGACCGCCGCCGATCTGCAACACGACCTTGACCGGCGCAAGCCCGGCCAGTCGC
GCTTCACCACCCAGCGCCGCGAGGACGATGCCGCCGAGATTTTGTCGGGGGTTTACGAGGGGGTGACGACGGGCACGCCG
ATCGCCGTGCTGATCCGCAATACGGACCAGCGCTCGAAGGATTATTCCGATATCGCCCAGCGCTTCCGCCCGGGGCATGC
CGATTACACCTATTGGGTCAAATACGGGGTGCGCGATCCGCGCGGCGGGGGGCGCTCCAGCGCCCGCGAGACCGCCGTGC
GCGTCGCCGCCGGAGCGATCGCCCGCAAGGTCTTGACCAGCGTGCTTGGCCGGCCGTTGACCATCCGCGCCGCCGTGGTG
GAAATGGGCGGGCTGGCGATCGAGCGGGCCAATTGGGATTGGCTTAGCGTCGACGCCAATCCGTTCTTCAGCCCCGATGC
GGCTATGGTCGCGCCGTGGGAGGCCTTGCTTGACGGGGTGCGCCGGGATGGCTCCAGCGTCGGGGCGGTGGTCGAGGTTG
TGGCCGAAGGCGTGCCGCCCGGACTGGGCGAGCCGGTTTATGACCGGCTGGATGCGGATCTGGCCAAGGCCCTTATGAGC
ATCAACGCCGTCAAGGGCGTTGAAATCGGCGCCGGCTTCGAAGCCGCCCGCTTGCGCGGCGAAAGTAACGCCGACGAGAT
GCTGCCCAACGGCCTGGGCGGTGTGCGCTTCACGTCCAATAACGCCGGCGGCGTGTTGGGCGGTATTTCCACCGGGCAGA
CGATCATCGCCCGACTGGCGGTCAAGCCGACCAGTTCAATCATGATCCCGCGCCAGAGCGTGGATACCCAGGGGCGGCCG
GTCGATGTGGTGACCAAGGGTCGGCATGATCCTTGTGTCGGCATTCGGGCGGTGCCGGTGGCCGAGGCCATGGTCGCCGT
TGTTCTGGCCGATCATCTTCTGCGCTTTCGCGGCCAGTGCGGTCTGCCCGTCGGGCTGTGA

Upstream 100 bases:

>100_bases
TCACGTGGATAGCGGCTATCATCTGGTGGGCATGCTGAACATGGACAGCGTCAGCGAGGTTTCCGCCCTGCTCGCCACCG
TCAAGAAGGATTAAGCCCCC

Downstream 100 bases:

>100_bases
GGCGGGGCGGGCGCCCCCCCCGCCTCAGCTGCGGGCCACGGGATCGGCGAGGCCGTAAAGGCGGCGCAGGGCGACGAGCT
GGCTGCGCAGGGCGCAGAGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAGDSFGTLFRFTSFGESHGPAIGCVVEGVPPGIPLTAADLQHDLDRRKPGQSRFTTQRREDDAAEILSGVYEGVTTGTP
IAVLIRNTDQRSKDYSDIAQRFRPGHADYTYWVKYGVRDPRGGGRSSARETAVRVAAGAIARKVLTSVLGRPLTIRAAVV
EMGGLAIERANWDWLSVDANPFFSPDAAMVAPWEALLDGVRRDGSSVGAVVEVVAEGVPPGLGEPVYDRLDADLAKALMS
INAVKGVEIGAGFEAARLRGESNADEMLPNGLGGVRFTSNNAGGVLGGISTGQTIIARLAVKPTSSIMIPRQSVDTQGRP
VDVVTKGRHDPCVGIRAVPVAEAMVAVVLADHLLRFRGQCGLPVGL

Sequences:

>Translated_366_residues
MAGDSFGTLFRFTSFGESHGPAIGCVVEGVPPGIPLTAADLQHDLDRRKPGQSRFTTQRREDDAAEILSGVYEGVTTGTP
IAVLIRNTDQRSKDYSDIAQRFRPGHADYTYWVKYGVRDPRGGGRSSARETAVRVAAGAIARKVLTSVLGRPLTIRAAVV
EMGGLAIERANWDWLSVDANPFFSPDAAMVAPWEALLDGVRRDGSSVGAVVEVVAEGVPPGLGEPVYDRLDADLAKALMS
INAVKGVEIGAGFEAARLRGESNADEMLPNGLGGVRFTSNNAGGVLGGISTGQTIIARLAVKPTSSIMIPRQSVDTQGRP
VDVVTKGRHDPCVGIRAVPVAEAMVAVVLADHLLRFRGQCGLPVGL
>Mature_365_residues
AGDSFGTLFRFTSFGESHGPAIGCVVEGVPPGIPLTAADLQHDLDRRKPGQSRFTTQRREDDAAEILSGVYEGVTTGTPI
AVLIRNTDQRSKDYSDIAQRFRPGHADYTYWVKYGVRDPRGGGRSSARETAVRVAAGAIARKVLTSVLGRPLTIRAAVVE
MGGLAIERANWDWLSVDANPFFSPDAAMVAPWEALLDGVRRDGSSVGAVVEVVAEGVPPGLGEPVYDRLDADLAKALMSI
NAVKGVEIGAGFEAARLRGESNADEMLPNGLGGVRFTSNNAGGVLGGISTGQTIIARLAVKPTSSIMIPRQSVDTQGRPV
DVVTKGRHDPCVGIRAVPVAEAMVAVVLADHLLRFRGQCGLPVGL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=63.2311977715877, Blast_Score=436, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321290, Length=363, Percent_Identity=43.801652892562, Blast_Score=287, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_RHORT (Q2RR25)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427707.1
- HSSP:   P63611
- ProteinModelPortal:   Q2RR25
- SMR:   Q2RR25
- STRING:   Q2RR25
- GeneID:   3836058
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2623
- NMPDR:   fig|1085.1.peg.274
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q2RR25
- ProtClustDB:   PRK05382
- BioCyc:   RRUB269796:RRU_A2623-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38647; Mature: 38516

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGDSFGTLFRFTSFGESHGPAIGCVVEGVPPGIPLTAADLQHDLDRRKPGQSRFTTQRR
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHC
EDDAAEILSGVYEGVTTGTPIAVLIRNTDQRSKDYSDIAQRFRPGHADYTYWVKYGVRDP
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCC
RGGGRSSARETAVRVAAGAIARKVLTSVLGRPLTIRAAVVEMGGLAIERANWDWLSVDAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCEEEEECCCCEEEECCC
PFFSPDAAMVAPWEALLDGVRRDGSSVGAVVEVVAEGVPPGLGEPVYDRLDADLAKALMS
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
INAVKGVEIGAGFEAARLRGESNADEMLPNGLGGVRFTSNNAGGVLGGISTGQTIIARLA
HHHHCCCEECCCCHHHHHCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHH
VKPTSSIMIPRQSVDTQGRPVDVVTKGRHDPCVGIRAVPVAEAMVAVVLADHLLRFRGQC
CCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCC
GLPVGL
CCCCCC
>Mature Secondary Structure 
AGDSFGTLFRFTSFGESHGPAIGCVVEGVPPGIPLTAADLQHDLDRRKPGQSRFTTQRR
CCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHC
EDDAAEILSGVYEGVTTGTPIAVLIRNTDQRSKDYSDIAQRFRPGHADYTYWVKYGVRDP
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCC
RGGGRSSARETAVRVAAGAIARKVLTSVLGRPLTIRAAVVEMGGLAIERANWDWLSVDAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCEEEEECCCCEEEECCC
PFFSPDAAMVAPWEALLDGVRRDGSSVGAVVEVVAEGVPPGLGEPVYDRLDADLAKALMS
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
INAVKGVEIGAGFEAARLRGESNADEMLPNGLGGVRFTSNNAGGVLGGISTGQTIIARLA
HHHHCCCEECCCCHHHHHCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCHHHHHHHHH
VKPTSSIMIPRQSVDTQGRPVDVVTKGRHDPCVGIRAVPVAEAMVAVVLADHLLRFRGQC
CCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCC
GLPVGL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA