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The map label for this gene is hlyU [H]

Identifier: 83593947

GI number: 83593947

Start: 3044004

End: 3044363

Strand: Reverse

Name: hlyU [H]

Synonym: Rru_A2615

Alternate gene names: 83593947

Gene position: 3044363-3044004 (Counterclockwise)

Preceding gene: 83593953

Following gene: 83593946

Centisome position: 69.94

GC content: 61.94

Gene sequence:

>360_bases
ATGGATATTGATCTTCTCGCCCTGCAAGGCCAGACCCAAAAAGGCAGCGCTTTGCTCAAAGCCATGAGCAATGAGCATCG
CTTGTTGATCTTATGCCACCTTATGCACCGCGAGCGGAGCGTCGGCGAATTAGAGCGGGTGGTTGGGCTGTCGCAATCGG
CGCTGTCCCAACATCTGGCCCGCCTGCGCAAGGACGGCGTGGTCAAGACCCGCCGGCAGGCCCAGACCATCTATTACTCG
CTGAACGGCCCCCAGGCCGGGGCCATTCTGCGCGTCTTGCATTCCCTGTATTGCGAAGACGCCGACACCGTCCCTTCGCG
AGGGCGCAAGCAGGCCGGCGGGCAGACCGACAGGCTGTGA

Upstream 100 bases:

>100_bases
GCGGGAAAATATGGTCGTAGTCCATCAACGCCTTTAGTCTCACTTGAGTTGTATCCCGATATTCCTCTAATTTAATGCCT
GATGAAAACAGGTAAAACCG

Downstream 100 bases:

>100_bases
GGAAATATTTTACAGCGATTTATTGTTAATTAAATCTTAATCACACAAATATTTGACGGTTGTCGATCGGGGATCTAGAG
TTTTCTCCGTCGCCCGCCCC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MDIDLLALQGQTQKGSALLKAMSNEHRLLILCHLMHRERSVGELERVVGLSQSALSQHLARLRKDGVVKTRRQAQTIYYS
LNGPQAGAILRVLHSLYCEDADTVPSRGRKQAGGQTDRL

Sequences:

>Translated_119_residues
MDIDLLALQGQTQKGSALLKAMSNEHRLLILCHLMHRERSVGELERVVGLSQSALSQHLARLRKDGVVKTRRQAQTIYYS
LNGPQAGAILRVLHSLYCEDADTVPSRGRKQAGGQTDRL
>Mature_119_residues
MDIDLLALQGQTQKGSALLKAMSNEHRLLILCHLMHRERSVGELERVVGLSQSALSQHLARLRKDGVVKTRRQAQTIYYS
LNGPQAGAILRVLHSLYCEDADTVPSRGRKQAGGQTDRL

Specific function: Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=96, Percent_Identity=47.9166666666667, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13215; Mature: 13215

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDLLALQGQTQKGSALLKAMSNEHRLLILCHLMHRERSVGELERVVGLSQSALSQHLA
CCCEEEEECCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
RLRKDGVVKTRRQAQTIYYSLNGPQAGAILRVLHSLYCEDADTVPSRGRKQAGGQTDRL
HHHHCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MDIDLLALQGQTQKGSALLKAMSNEHRLLILCHLMHRERSVGELERVVGLSQSALSQHLA
CCCEEEEECCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
RLRKDGVVKTRRQAQTIYYSLNGPQAGAILRVLHSLYCEDADTVPSRGRKQAGGQTDRL
HHHHCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]