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The map label for this gene is 83593945

Identifier: 83593945

GI number: 83593945

Start: 3040435

End: 3041973

Strand: Reverse

Name: 83593945

Synonym: Rru_A2613

Alternate gene names: NA

Gene position: 3041973-3040435 (Counterclockwise)

Preceding gene: 83593946

Following gene: 83593944

Centisome position: 69.89

GC content: 66.15

Gene sequence:

>1539_bases
ATGATCCCGAAGTCACAACGCGCCGTTTTCACCTTTCTCGCCAAGCCCGAAACCCACGGGCCGGGCGTCGATCGGGTCGA
TCAGGTCCATACCCATATTTCGGCTTTGTTTCTGGCCGGCGAGCGGGTTTTGAAGCTGAAGAGGGCGGTGGCGCTGCCCT
ATCTCGATCACACCACCCTGGCGGCGCGCAAAGCCTGCTGCGAGCGCGAAGTGGCGATCAACGCCCCCGGCGCGCCGGGG
CTTTATCGGGGCGTCCTGCCCGTAACCCGCGAGAGCGACGGCACCCTGGCCCTGGATGGCGCCGGGGAGCCGGTGGAATG
GCTGGTCGTCATGAACCGCTTTGATGAAGGGGCGCTGTTTGATCGCCGCCTTGCCCTGGGCCATCTGGATCGCCATCAGA
TGAGCGATCTGGCCGAGGTGATCTTCGCCGCCCACGAGCGGGCCGAGAGGATCGACGATGACCATGGCCTGGGCTTCGGC
CGCAATCTGGAAGGCGCCCTGGCCGAACTGGCCGAACAGCGCGGGCTTCTGGGCGAGGCCCTGAGCGACGAGGTCGCGGC
CGCCTTGCGCGCCGCCCATCAGCGCCTCAAGCCGCTGTTGGCCGAGCGGGCGGCGGCCGGGCGGGTGCGGCGCTGCCATG
GCGATCTGCATTTGCGCAATATCGTGCTGTGGGACAATCGCCCGGCTCTGTTCGATGCCATCGATTTCACCGAGACCTTC
GCCCGCATCGATGTGCTTTATGATCTGGCCTATCTGCTGATGGATCTCGATTACCGGGGGCACCGCCGGCTGGCCTCGAT
CACCTTCAACCATTATATGGAATTCGCCGGCGATACCGGGGGGCTTGCGGCCTTGCCGCTGTTCCTGGCCCTGCGCGCCA
CCATTCGCGCCTTTGTCACCGCCGCCGGCGCCGCCAACCAATCCGATGGTGATGAAGCCGCCAAACTCATCGCCGAGGGC
CGCCGCTATCTGGCCCAGGCCACGGGCTATCTGACCCCCGGGTCCCCCCGTATGGTCGCCGTGGGCGGATTATCGGGCAG
CGGCAAGTCGCGGCTGGCCCGTGAAATCGCCCCCCATCTGGGCTGCGCCCCCGGCGCCCTGGTTTTGCGCACCGATGTGT
TGCGCAAGCGCCTGATGGGATTGTCGCCCTATCAAAGCCTGGGGCCCGAGGGCTATACGCCAGAGATGCATGCCCGCACC
TATCAGAGGCTCGAAGCCGAGGCCCGGTTGGCTTTGGCTTGCGGCCATTCGGTGGTGCTGGACGGCGTTCACGCCAGACC
GGGCGAAAGGGCCAATGCCGAACGCATCGCAGCCGAGGCCGGGGTGCCCTTCGCCGGGCTGTGGGTGCATACCCCCGTCG
ATCTGGCCATGCGGCGGATCGAAACCCGGGTGCGCAATCCCTCGGATGTCACCTTGGCGGTTCGCGCCAATCAAGAGGAT
TTCGATCTGGGGGCGGTGACCTGGGCCCGGGTGGATTCATCGGGCCCCAAGAAGGACACGGTGATCGCCGGATTGGCCGC
TTTGGGGCTAAGTAGTTGA

Upstream 100 bases:

>100_bases
CGACCGCCACCGCCGCGGTCTTTCAGCTTCCTCTGGTGGTGGCGGGCGGGCTGTGGCACTCTGGGTCAGGCTCAACAACG
GCCGCACCGCGGCACAGGCG

Downstream 100 bases:

>100_bases
CCTTCATCCTTTTATTGCGTTCTCTCCGGGCGCATAATGATCCCTGACGTTTTCTAGGTCTATCAAGATCAGGAGTATCG
CGATGACCGGCATCCGCACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MIPKSQRAVFTFLAKPETHGPGVDRVDQVHTHISALFLAGERVLKLKRAVALPYLDHTTLAARKACCEREVAINAPGAPG
LYRGVLPVTRESDGTLALDGAGEPVEWLVVMNRFDEGALFDRRLALGHLDRHQMSDLAEVIFAAHERAERIDDDHGLGFG
RNLEGALAELAEQRGLLGEALSDEVAAALRAAHQRLKPLLAERAAAGRVRRCHGDLHLRNIVLWDNRPALFDAIDFTETF
ARIDVLYDLAYLLMDLDYRGHRRLASITFNHYMEFAGDTGGLAALPLFLALRATIRAFVTAAGAANQSDGDEAAKLIAEG
RRYLAQATGYLTPGSPRMVAVGGLSGSGKSRLAREIAPHLGCAPGALVLRTDVLRKRLMGLSPYQSLGPEGYTPEMHART
YQRLEAEARLALACGHSVVLDGVHARPGERANAERIAAEAGVPFAGLWVHTPVDLAMRRIETRVRNPSDVTLAVRANQED
FDLGAVTWARVDSSGPKKDTVIAGLAALGLSS

Sequences:

>Translated_512_residues
MIPKSQRAVFTFLAKPETHGPGVDRVDQVHTHISALFLAGERVLKLKRAVALPYLDHTTLAARKACCEREVAINAPGAPG
LYRGVLPVTRESDGTLALDGAGEPVEWLVVMNRFDEGALFDRRLALGHLDRHQMSDLAEVIFAAHERAERIDDDHGLGFG
RNLEGALAELAEQRGLLGEALSDEVAAALRAAHQRLKPLLAERAAAGRVRRCHGDLHLRNIVLWDNRPALFDAIDFTETF
ARIDVLYDLAYLLMDLDYRGHRRLASITFNHYMEFAGDTGGLAALPLFLALRATIRAFVTAAGAANQSDGDEAAKLIAEG
RRYLAQATGYLTPGSPRMVAVGGLSGSGKSRLAREIAPHLGCAPGALVLRTDVLRKRLMGLSPYQSLGPEGYTPEMHART
YQRLEAEARLALACGHSVVLDGVHARPGERANAERIAAEAGVPFAGLWVHTPVDLAMRRIETRVRNPSDVTLAVRANQED
FDLGAVTWARVDSSGPKKDTVIAGLAALGLSS
>Mature_512_residues
MIPKSQRAVFTFLAKPETHGPGVDRVDQVHTHISALFLAGERVLKLKRAVALPYLDHTTLAARKACCEREVAINAPGAPG
LYRGVLPVTRESDGTLALDGAGEPVEWLVVMNRFDEGALFDRRLALGHLDRHQMSDLAEVIFAAHERAERIDDDHGLGFG
RNLEGALAELAEQRGLLGEALSDEVAAALRAAHQRLKPLLAERAAAGRVRRCHGDLHLRNIVLWDNRPALFDAIDFTETF
ARIDVLYDLAYLLMDLDYRGHRRLASITFNHYMEFAGDTGGLAALPLFLALRATIRAFVTAAGAANQSDGDEAAKLIAEG
RRYLAQATGYLTPGSPRMVAVGGLSGSGKSRLAREIAPHLGCAPGALVLRTDVLRKRLMGLSPYQSLGPEGYTPEMHART
YQRLEAEARLALACGHSVVLDGVHARPGERANAERIAAEAGVPFAGLWVHTPVDLAMRRIETRVRNPSDVTLAVRANQED
FDLGAVTWARVDSSGPKKDTVIAGLAALGLSS

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 55437; Mature: 55437

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPKSQRAVFTFLAKPETHGPGVDRVDQVHTHISALFLAGERVLKLKRAVALPYLDHTTL
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AARKACCEREVAINAPGAPGLYRGVLPVTRESDGTLALDGAGEPVEWLVVMNRFDEGALF
HHHHHHHHCCCEECCCCCCCHHHCCCCEEECCCCCEEECCCCCCHHHHHHHHHCCCCCHH
DRRLALGHLDRHQMSDLAEVIFAAHERAERIDDDHGLGFGRNLEGALAELAEQRGLLGEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
LSDEVAAALRAAHQRLKPLLAERAAAGRVRRCHGDLHLRNIVLWDNRPALFDAIDFTETF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHH
ARIDVLYDLAYLLMDLDYRGHRRLASITFNHYMEFAGDTGGLAALPLFLALRATIRAFVT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AAGAANQSDGDEAAKLIAEGRRYLAQATGYLTPGSPRMVAVGGLSGSGKSRLAREIAPHL
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
GCAPGALVLRTDVLRKRLMGLSPYQSLGPEGYTPEMHARTYQRLEAEARLALACGHSVVL
CCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEE
DGVHARPGERANAERIAAEAGVPFAGLWVHTPVDLAMRRIETRVRNPSDVTLAVRANQED
CCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCC
FDLGAVTWARVDSSGPKKDTVIAGLAALGLSS
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIPKSQRAVFTFLAKPETHGPGVDRVDQVHTHISALFLAGERVLKLKRAVALPYLDHTTL
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AARKACCEREVAINAPGAPGLYRGVLPVTRESDGTLALDGAGEPVEWLVVMNRFDEGALF
HHHHHHHHCCCEECCCCCCCHHHCCCCEEECCCCCEEECCCCCCHHHHHHHHHCCCCCHH
DRRLALGHLDRHQMSDLAEVIFAAHERAERIDDDHGLGFGRNLEGALAELAEQRGLLGEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
LSDEVAAALRAAHQRLKPLLAERAAAGRVRRCHGDLHLRNIVLWDNRPALFDAIDFTETF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHH
ARIDVLYDLAYLLMDLDYRGHRRLASITFNHYMEFAGDTGGLAALPLFLALRATIRAFVT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AAGAANQSDGDEAAKLIAEGRRYLAQATGYLTPGSPRMVAVGGLSGSGKSRLAREIAPHL
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
GCAPGALVLRTDVLRKRLMGLSPYQSLGPEGYTPEMHARTYQRLEAEARLALACGHSVVL
CCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEE
DGVHARPGERANAERIAAEAGVPFAGLWVHTPVDLAMRRIETRVRNPSDVTLAVRANQED
CCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCC
FDLGAVTWARVDSSGPKKDTVIAGLAALGLSS
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]