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The map label for this gene is rbsK [H]

Identifier: 83593632

GI number: 83593632

Start: 2658200

End: 2659129

Strand: Reverse

Name: rbsK [H]

Synonym: Rru_A2297

Alternate gene names: 83593632

Gene position: 2659129-2658200 (Counterclockwise)

Preceding gene: 83593633

Following gene: 83593628

Centisome position: 61.09

GC content: 65.7

Gene sequence:

>930_bases
ATGTCGGGCAGGATCGCCGTTGTCGGCAGCAATATGGTTGACCTGATTACCTATGTCACCCGCATGCCCGACAAGGGCGA
GACCATCGAGGCGCCGAACTTCGCCCTGGGCTGCGGCGGCAAGGGGGCCAATCAGGCGATCGCCGCCGCCCGCTTGGGCG
CCGATGTGCTGATGGTCACCCGGGTTGGCGATGACATCTTCGCCGACAATACCATCGCCAATTTCAAGGCCAATGGCATC
GATACCCGCTTTGTGCGCAAGGTTCCGGGCACGCCGAGCGGCGTCGCGCCGATCTTCGTCGAACAAAACGGCGAAAACTC
GATCCTGATCGTCAAGGGCGCCAATGCCCATCTATCGCCGGCCGATGTCGAGGAGGCCGGCGAGGCGCTGAAAGGCTGCG
CCCTGATCCTGATGCAGCTCGAAGTGCCCCTGGAAACCATCTATGCCACGGTGGCCTTTGGCGCGGCGCACGGCATTCCG
ACCTTGCTCAATCCCGCCCCGGCGGTGCCCGAGCTCGATGTCGAGCGCCTGCGCACGCTCTCCTTCCTGACCCCCAATGA
AACCGAACTGGCGATCTTGTCGGGGATGCCGGTGGCGAGCGAAACCGAGGTCGAGGCCGCCGCCCGCAGCCTGATCGCCA
AGGGCGTGCGCACGGTGATCGTCACCATGGGCGCGCGCGGCGCCTTGCTGGTCGAGGAAAAGGGCGCCACCCGCATCGCG
CCGGTCCGCGTGACCCCCAAGGACACCACCGGGGCGGGCGACGCCTTCATCGGCAGCTTCGCCCATTACTATACGCAAAA
CGGCGATATCGCCGCCGCCCTGCGCAAGGCGGTGCGCTATGCCGCCGATTCGATCACCCGCAACGGCACCCAAAGCTCCT
ATGCCACCCTGGCCGAGTTCGAGGCCTTCTGCGCGACGATCGACGCCTAG

Upstream 100 bases:

>100_bases
GGCGGCCTTCGCCGTGACTTTGGGCTATCTCGATGAACCGGCGGCCGAGGCCGCCGAACGGGCGATCAAGGCCCTGTCTT
TTGGTAAGGGAGCTTAGAGG

Downstream 100 bases:

>100_bases
GGAAAGGCACGGTCTGGCGGAAAAGCGGTCGTCCCTTTTCCGCCAGGGTCTGGGTTAGCGGGCTCCCATCACGTCGCGGT
CGCGCAGGGCGCCCCGGGTG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVTRVGDDIFADNTIANFKANGI
DTRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSPADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIP
TLLNPAPAVPELDVERLRTLSFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIA
PVRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEFEAFCATIDA

Sequences:

>Translated_309_residues
MSGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVTRVGDDIFADNTIANFKANGI
DTRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSPADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIP
TLLNPAPAVPELDVERLRTLSFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIA
PVRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEFEAFCATIDA
>Mature_308_residues
SGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVTRVGDDIFADNTIANFKANGID
TRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSPADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIPT
LLNPAPAVPELDVERLRTLSFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIAP
VRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEFEAFCATIDA

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=290, Percent_Identity=38.6206896551724, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=37.953795379538, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87082343, Length=307, Percent_Identity=30.6188925081433, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788491, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=38.3333333333333, Blast_Score=205, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=28.4829721362229, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=37.2093023255814, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=31.8791946308725, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32220; Mature: 32089

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVT
CCCEEEEECCCHHHHHHHHHHCCCCCCEECCCCEEEECCCCCCHHHHHHHHHCCCEEEEE
RVGDDIFADNTIANFKANGIDTRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSP
ECCCCHHCCCCEECEECCCCCHHHHEECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCC
ADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIPTLLNPAPAVPELDVERLRTL
CCHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHH
SFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIA
HCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCEEE
PVRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEF
EEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EAFCATIDA
HHHHHCCCC
>Mature Secondary Structure 
SGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVT
CCEEEEECCCHHHHHHHHHHCCCCCCEECCCCEEEECCCCCCHHHHHHHHHCCCEEEEE
RVGDDIFADNTIANFKANGIDTRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSP
ECCCCHHCCCCEECEECCCCCHHHHEECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCC
ADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIPTLLNPAPAVPELDVERLRTL
CCHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHH
SFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIA
HCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCEEE
PVRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEF
EEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EAFCATIDA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]