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The map label for this gene is fixC [H]

Identifier: 83593600

GI number: 83593600

Start: 2625230

End: 2626531

Strand: Reverse

Name: fixC [H]

Synonym: Rru_A2265

Alternate gene names: 83593600

Gene position: 2626531-2625230 (Counterclockwise)

Preceding gene: 83593601

Following gene: 83593599

Centisome position: 60.34

GC content: 63.13

Gene sequence:

>1302_bases
ATGGCAGAGCATTTCGATGTAATCATCGTCGGTGCGGGCATGGCGGGCAACGCCGCCTCCTACACCCTGGCCAAGGCCGG
CCTCAACGTCTTGCAGATCGAGCGCGGCGAATATCCCGGGTCGAAGAACGTTCAGGGCGCCATTCTGTACGCCAATGCGG
TCGAGCAGATCATTCCCGGCTTCCGCGATGACGCGCCGCTGGAACGCCACGTCATCGAACAGCGCATGTGGATGCTCGAT
GACCGCTCCTATGTGGGCAGCCATTTCCGCAGCGAGAACTTCAACGAGGAAAAGCCCAACCGCTACACCATCATCCGCGC
CCAGTTCGACAAGTGGTTCAACCGTCAGGCCCGCGACGCCGGGGCGATGGTGATCTGCGAGACCACCGTGCTCGATCTGA
TCCGCAACGATGCCGGCAAGGTGGTGGGCGTGCGCTGCGACCGCGAGGGCGGCGAGGTCTATGCCGAGGTGGTCATCCTC
TGCGACGGCGTCAACGCCCTGGTCGGCCAGCGCTCGGGCATCCGCTCCGAGATCAGCCCCGAGCACGCCGCCCTGGCGGT
CAAGGAGATGCACTTCCTGCCGCGCGAGGTCATCAACGAGCGCTTCAACGTGCGCGATGACGAAGGCGTGGTCATCGAGG
CCCTGGGCACCGTGACCTCGGGCATGTTGGGCACCGGCTTCCTCTATACCAATGGCGAGAGCATCTCGCTGGGCATCGGC
TGCATCGTGTCCGATTTCGTCGAGACCAAGATCGGTCCGGCCAAGCTGCTTGAACGCTTCAAGGCCCATCCCTCGATCGC
TCCGCTGATCAGGGGCTCCGAGGTCAAGGAATACGCCGCCCATCTGATCCCCGAAGGCGGCTATAACGCGGTGCCCCAGC
TTTACGGCGCCGGCTGGCTGATCTGCGGCGATGCCGCCCACTTCCTCAACGCCGCCCACCGCGAGGGCTCCAATCTGGCG
CTCACCTCCGGGCGGCTGGCGGCGGAAACGATCATCGCGCTGAAGTCCGAAGGCAAGGCGATGACCGAGGCCAATCTGGC
GCTCTATCGCCAGAAGCTTGAGGAAAGCTTCGTGCTGAAGGACCTGAAGAAGTATAAGGACCTTCCCCACACCCTGTGGC
GCAACAAGCAGTTCGTGACGACCTATCCCGAATTGATGGCCAAGGCGGCGGAGAATTTCTTCCGCGTCGATGGTGTCGAT
AAGCTGACCAAGGAAAAAGACATCGTGCGGAGCTTCCGCAAGGCCCGGGGTGTTCTCGGTCTGGTGGGCGACGCCGTCAA
GGTGGCGAGGGCATGGCGATGA

Upstream 100 bases:

>100_bases
GGTCGGCGACGCGACCCGTATTCTTCCGGCCCTGACCAAGGCGTTCGAAGCGCGCCTCGCGGTCCGGCGGATGGCGAGCT
GATCGAAAGGATCAACGATC

Downstream 100 bases:

>100_bases
GCGACAAAATCGAAGAAAAGCTGTATCAGAACCGCTATCGGGTTGACGAGGGCTGTCCCCACGTCCGTATCGATGCGTCC
AAGGTCCCCTCCGAGCAGTT

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MAEHFDVIIVGAGMAGNAASYTLAKAGLNVLQIERGEYPGSKNVQGAILYANAVEQIIPGFRDDAPLERHVIEQRMWMLD
DRSYVGSHFRSENFNEEKPNRYTIIRAQFDKWFNRQARDAGAMVICETTVLDLIRNDAGKVVGVRCDREGGEVYAEVVIL
CDGVNALVGQRSGIRSEISPEHAALAVKEMHFLPREVINERFNVRDDEGVVIEALGTVTSGMLGTGFLYTNGESISLGIG
CIVSDFVETKIGPAKLLERFKAHPSIAPLIRGSEVKEYAAHLIPEGGYNAVPQLYGAGWLICGDAAHFLNAAHREGSNLA
LTSGRLAAETIIALKSEGKAMTEANLALYRQKLEESFVLKDLKKYKDLPHTLWRNKQFVTTYPELMAKAAENFFRVDGVD
KLTKEKDIVRSFRKARGVLGLVGDAVKVARAWR

Sequences:

>Translated_433_residues
MAEHFDVIIVGAGMAGNAASYTLAKAGLNVLQIERGEYPGSKNVQGAILYANAVEQIIPGFRDDAPLERHVIEQRMWMLD
DRSYVGSHFRSENFNEEKPNRYTIIRAQFDKWFNRQARDAGAMVICETTVLDLIRNDAGKVVGVRCDREGGEVYAEVVIL
CDGVNALVGQRSGIRSEISPEHAALAVKEMHFLPREVINERFNVRDDEGVVIEALGTVTSGMLGTGFLYTNGESISLGIG
CIVSDFVETKIGPAKLLERFKAHPSIAPLIRGSEVKEYAAHLIPEGGYNAVPQLYGAGWLICGDAAHFLNAAHREGSNLA
LTSGRLAAETIIALKSEGKAMTEANLALYRQKLEESFVLKDLKKYKDLPHTLWRNKQFVTTYPELMAKAAENFFRVDGVD
KLTKEKDIVRSFRKARGVLGLVGDAVKVARAWR
>Mature_432_residues
AEHFDVIIVGAGMAGNAASYTLAKAGLNVLQIERGEYPGSKNVQGAILYANAVEQIIPGFRDDAPLERHVIEQRMWMLDD
RSYVGSHFRSENFNEEKPNRYTIIRAQFDKWFNRQARDAGAMVICETTVLDLIRNDAGKVVGVRCDREGGEVYAEVVILC
DGVNALVGQRSGIRSEISPEHAALAVKEMHFLPREVINERFNVRDDEGVVIEALGTVTSGMLGTGFLYTNGESISLGIGC
IVSDFVETKIGPAKLLERFKAHPSIAPLIRGSEVKEYAAHLIPEGGYNAVPQLYGAGWLICGDAAHFLNAAHREGSNLAL
TSGRLAAETIIALKSEGKAMTEANLALYRQKLEESFVLKDLKKYKDLPHTLWRNKQFVTTYPELMAKAAENFFRVDGVDK
LTKEKDIVRSFRKARGVLGLVGDAVKVARAWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=399, Percent_Identity=26.3157894736842, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=39.9532710280374, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1787991, Length=431, Percent_Identity=40.1392111368909, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI87082155, Length=415, Percent_Identity=33.0120481927711, Blast_Score=224, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI25144720, Length=394, Percent_Identity=23.6040609137056, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324932, Length=415, Percent_Identity=25.3012048192771, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652256, Length=403, Percent_Identity=23.3250620347395, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 47812; Mature: 47681

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHFDVIIVGAGMAGNAASYTLAKAGLNVLQIERGEYPGSKNVQGAILYANAVEQIIPG
CCCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHCCC
FRDDAPLERHVIEQRMWMLDDRSYVGSHFRSENFNEEKPNRYTIIRAQFDKWFNRQARDA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHCHHHCCC
GAMVICETTVLDLIRNDAGKVVGVRCDREGGEVYAEVVILCDGVNALVGQRSGIRSEISP
CCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEECCHHHHHCCCCCCCCCCCC
EHAALAVKEMHFLPREVINERFNVRDDEGVVIEALGTVTSGMLGTGFLYTNGESISLGIG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHCCEEEECCCEEEEHHH
CIVSDFVETKIGPAKLLERFKAHPSIAPLIRGSEVKEYAAHLIPEGGYNAVPQLYGAGWL
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCCEE
ICGDAAHFLNAAHREGSNLALTSGRLAAETIIALKSEGKAMTEANLALYRQKLEESFVLK
EECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DLKKYKDLPHTLWRNKQFVTTYPELMAKAAENFFRVDGVDKLTKEKDIVRSFRKARGVLG
HHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCHH
LVGDAVKVARAWR
HHHHHHHHHHCCC
>Mature Secondary Structure 
AEHFDVIIVGAGMAGNAASYTLAKAGLNVLQIERGEYPGSKNVQGAILYANAVEQIIPG
CCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHCCC
FRDDAPLERHVIEQRMWMLDDRSYVGSHFRSENFNEEKPNRYTIIRAQFDKWFNRQARDA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHCHHHCCC
GAMVICETTVLDLIRNDAGKVVGVRCDREGGEVYAEVVILCDGVNALVGQRSGIRSEISP
CCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEECCHHHHHCCCCCCCCCCCC
EHAALAVKEMHFLPREVINERFNVRDDEGVVIEALGTVTSGMLGTGFLYTNGESISLGIG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHCCEEEECCCEEEEHHH
CIVSDFVETKIGPAKLLERFKAHPSIAPLIRGSEVKEYAAHLIPEGGYNAVPQLYGAGWL
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCHHHHCCCEE
ICGDAAHFLNAAHREGSNLALTSGRLAAETIIALKSEGKAMTEANLALYRQKLEESFVLK
EECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DLKKYKDLPHTLWRNKQFVTTYPELMAKAAENFFRVDGVDKLTKEKDIVRSFRKARGVLG
HHHHHHCCCHHHHCCCCEEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCHH
LVGDAVKVARAWR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]