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The map label for this gene is paaG [H]

Identifier: 83593575

GI number: 83593575

Start: 2600660

End: 2601478

Strand: Reverse

Name: paaG [H]

Synonym: Rru_A2240

Alternate gene names: 83593575

Gene position: 2601478-2600660 (Counterclockwise)

Preceding gene: 83593576

Following gene: 83593574

Centisome position: 59.77

GC content: 69.72

Gene sequence:

>819_bases
ATGGCCGATCCCGCGACTTCCCTTGCCAGTCCGCTTGATACGCGTCGTCACGGCGGCGTGCTGGTTTTGACGATGAACGA
TCCGGCCACCCGCAACGCCCTCAGTCCGACGGTGTTCGCCGCCGGCACCCGCGCCCTGGCCGAAGCGGCGGACGATGACG
GCATCGGCGCCGTGGTGCTGACGGGGGCGAATGGGGCGTTTTGTTCGGGGGGCGATCTGCGGCTGCTGGCCGGGGCGCCC
AGCGACATCACCGCCTTGCTCGACTCGTTTCACGGCTTCGTCCGCGCCATCCGCGCCTTGCCGCTGCCGGTGATCGCCGC
CGTCGAGGGATCGGCGGCCGGCGCTGGGTTTTCGCTGGCTTTGGGCTGCGACCTGCTGGTCGCCTCACGCGAGGCCAGCT
TCCTGATGGCCTATATCAAGGTCGGTCTCACCCCCGATGGCGGGGCGACGGCTTTCCTCGCCCGCGCCCTGCCGCGCGCC
CTTCAAACCGAGATCGTCCTGACCGGCGCGCCGGTTTCGGCCGAGCGCCTGCATGGCTTGGGCGTGGTCAACCGCCTTGT
CGAGCCCGGAACGGCCTGTGAGGCCGCCTTGGCCTGGGCCGCGGCCTTCGCCGCCGGCCCGCGCGCCGCCCTCGGCCGAG
CCAAGCGTTTGGTCGAGGCGGCCGGCTCCAATGACTTGGAAGGTCAGCTTGATCTGGAGGCCGCGCTGTTTAGCCAAGCG
ATCGCCCATGGCGAAGCCCGCGAGGGGATGACCGCCTTTTTGCACAAGCGCAGCCCCGATTTCGCCGCCGCGCGCGGCCG
GATGGGTCAAAAGATTTAA

Upstream 100 bases:

>100_bases
GCGCCGTGATCGCGACCCCAGGCTCCCGTCGGGGTTGTTAAAAGGCCTCGCCGGACAAGAACTTTGCGCTACCATGGGGG
CTCCATCAACGGAGGACCCC

Downstream 100 bases:

>100_bases
AAATTTCTCAATGACAGGGGTGGACGCAGCTTTGTACCATCCCGCCTTCGGAAAACAGACCAAAAACCACCGAAGGGACA
GTCCATGAGAAAGCTATTCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MADPATSLASPLDTRRHGGVLVLTMNDPATRNALSPTVFAAGTRALAEAADDDGIGAVVLTGANGAFCSGGDLRLLAGAP
SDITALLDSFHGFVRAIRALPLPVIAAVEGSAAGAGFSLALGCDLLVASREASFLMAYIKVGLTPDGGATAFLARALPRA
LQTEIVLTGAPVSAERLHGLGVVNRLVEPGTACEAALAWAAAFAAGPRAALGRAKRLVEAAGSNDLEGQLDLEAALFSQA
IAHGEAREGMTAFLHKRSPDFAAARGRMGQKI

Sequences:

>Translated_272_residues
MADPATSLASPLDTRRHGGVLVLTMNDPATRNALSPTVFAAGTRALAEAADDDGIGAVVLTGANGAFCSGGDLRLLAGAP
SDITALLDSFHGFVRAIRALPLPVIAAVEGSAAGAGFSLALGCDLLVASREASFLMAYIKVGLTPDGGATAFLARALPRA
LQTEIVLTGAPVSAERLHGLGVVNRLVEPGTACEAALAWAAAFAAGPRAALGRAKRLVEAAGSNDLEGQLDLEAALFSQA
IAHGEAREGMTAFLHKRSPDFAAARGRMGQKI
>Mature_271_residues
ADPATSLASPLDTRRHGGVLVLTMNDPATRNALSPTVFAAGTRALAEAADDDGIGAVVLTGANGAFCSGGDLRLLAGAPS
DITALLDSFHGFVRAIRALPLPVIAAVEGSAAGAGFSLALGCDLLVASREASFLMAYIKVGLTPDGGATAFLARALPRAL
QTEIVLTGAPVSAERLHGLGVVNRLVEPGTACEAALAWAAAFAAGPRAALGRAKRLVEAAGSNDLEGQLDLEAALFSQAI
AHGEAREGMTAFLHKRSPDFAAARGRMGQKI

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=32.9268292682927, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=30.078125, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI221136756, Length=252, Percent_Identity=25.7936507936508, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI221136753, Length=252, Percent_Identity=25.7936507936508, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI221307494, Length=252, Percent_Identity=25.7936507936508, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI116235487, Length=248, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4502327, Length=250, Percent_Identity=28.4, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4757968, Length=253, Percent_Identity=23.7154150197628, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI49355787, Length=253, Percent_Identity=23.7154150197628, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI25453481, Length=253, Percent_Identity=23.3201581027668, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI51538573, Length=253, Percent_Identity=23.3201581027668, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20127408, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI68989263, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4757966, Length=242, Percent_Identity=23.9669421487603, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538581, Length=242, Percent_Identity=23.9669421487603, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI260274832, Length=248, Percent_Identity=25.4032258064516, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI45643119, Length=247, Percent_Identity=25.5060728744939, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI260275230, Length=247, Percent_Identity=25.5060728744939, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI70995211, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI213417737, Length=199, Percent_Identity=25.1256281407035, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI157694516, Length=199, Percent_Identity=25.1256281407035, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=248, Percent_Identity=39.1129032258064, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=35.5212355212355, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=32.295719844358, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=31.3953488372093, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=26.7015706806283, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=243, Percent_Identity=31.2757201646091, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=29.2682926829268, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=243, Percent_Identity=30.0411522633745, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=202, Percent_Identity=28.2178217821782, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=260, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=22.9249011857708, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=195, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=27.1889400921659, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=182, Percent_Identity=28.021978021978, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=230, Percent_Identity=23.4782608695652, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=31.3207547169811, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=27.2, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20129971, Length=240, Percent_Identity=29.1666666666667, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24653477, Length=240, Percent_Identity=29.1666666666667, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=25.5905511811024, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357171, Length=251, Percent_Identity=30.2788844621514, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24650670, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27545; Mature: 27414

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPATSLASPLDTRRHGGVLVLTMNDPATRNALSPTVFAAGTRALAEAADDDGIGAVVL
CCCCHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
TGANGAFCSGGDLRLLAGAPSDITALLDSFHGFVRAIRALPLPVIAAVEGSAAGAGFSLA
ECCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
LGCDLLVASREASFLMAYIKVGLTPDGGATAFLARALPRALQTEIVLTGAPVSAERLHGL
CCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHH
GVVNRLVEPGTACEAALAWAAAFAAGPRAALGRAKRLVEAAGSNDLEGQLDLEAALFSQA
HHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IAHGEAREGMTAFLHKRSPDFAAARGRMGQKI
HHCCCHHCCHHHHHHCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
ADPATSLASPLDTRRHGGVLVLTMNDPATRNALSPTVFAAGTRALAEAADDDGIGAVVL
CCCHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
TGANGAFCSGGDLRLLAGAPSDITALLDSFHGFVRAIRALPLPVIAAVEGSAAGAGFSLA
ECCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
LGCDLLVASREASFLMAYIKVGLTPDGGATAFLARALPRALQTEIVLTGAPVSAERLHGL
CCCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHH
GVVNRLVEPGTACEAALAWAAAFAAGPRAALGRAKRLVEAAGSNDLEGQLDLEAALFSQA
HHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IAHGEAREGMTAFLHKRSPDFAAARGRMGQKI
HHCCCHHCCHHHHHHCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]