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The map label for this gene is siaT [H]

Identifier: 83593572

GI number: 83593572

Start: 2597699

End: 2598982

Strand: Reverse

Name: siaT [H]

Synonym: Rru_A2237

Alternate gene names: 83593572

Gene position: 2598982-2597699 (Counterclockwise)

Preceding gene: 83593573

Following gene: 83593570

Centisome position: 59.71

GC content: 65.81

Gene sequence:

>1284_bases
ATGGCTACCCTGTCGCTGTTTGCCGTGTTCCTGGGCTTGACGCTTCTTGGCGCGCCGCTGGCCGTCGCCCTGGGCCTTGC
CGGATCGGTGGCGATCCTCGAGGCCCAGCTTGGCATTCTTTCAGTGCCGACCACGGTGTATGCGGGCATCGCCAAATATC
CGCTGCTGGCGATCCCGGTGTTCATTCTGGCCGGCCTGATCTTCGAGCGCGTCGGGGTGGCCCGCCAGTTGGTCTCCTTC
GCCTCGTCGATCGTTGGGGCGCGCAACGGCGGCTTGGCCATCGTCGCCGTTCTGGTCTGCATGGTCATGGGCGGCATTTC
GGGATCGGGTCCGGCCGATGCGGCGGCGGTCGCCACGGTGATGATCCCCAGCCTTCACAAGGCCGGCTATCCCAAGGCCT
TTTCGGCCAGCGTCATCGCCGCCGGGGCGGCGACGGCCATTCTGATCCCGCCCTCGGTCGCCTTCATCATTTATAGCGTT
CTCGTCCCCCAGGCCTCGGTTCCGGCGCTGTTCGCCGGCGGCTTGATCCCCGGCCTGCTCGCCGGGCTGTCGTTGCTGGC
ACCGATCGTTTATCTGTCGCGCCGTCATGGCTTCGGCATGGCCGACAGCGGCCCGCGACCGGGCTTCTGGGTCAGCCTCA
AGGGGGCGATCTGGGGGCTGCTCGCTCCGGTGATCATCCTGGGCGGCCTGCGGCTCGGTCTCTTCACCCCGACCGAAGCG
GCGGTGGTCGCCGTTTTCTATGGGCTGTTCGTCGGCGTCTTCATCCTGCGCACGCTGTCGGGACGGATGCTTATCGACAT
GCTGGCCGATGCCGCCGAGATGTCGGGGGTGGTGCTGCTGATCATCGCCCTGGCCAGCGTTTTCGCCTGGGCCGGCAGTA
CCTTGGGCGCTTTTGACGCCGTGGCCGGAGCGGCGCTGCAGGCGACGGACAACGAAGTCGTTGTCTTGTTGATGCTCAAC
CTTTTGCTGCTCGGCCTGGGAATGGTGCTGGACGCGGTTTCGATCTTCCTGATCTTGCTGCCGCTGCTCGTTCCCTTCAT
GGAAGCCTTCCACTGGGATCCGGTCTGGTTCGGGGTGATGGTGACGATGAACCTCGCCGTCGGCCAGTTCACGCCGCCGA
TGGCGGTCAATCTGATGGTGACCACCCGCATCGCCGGGGTCCGCATGGAGGCGGCGACCGGCTGGACGCTGTGGTTCGTG
GGCGCCATGATCGTGGCGCTGATGGTCGTAACCTTCGTGCCCGAACTCACCCTGTGGCTGCCGCGGGCTTTGGGCTATCT
GTGA

Upstream 100 bases:

>100_bases
ATCCCCAATGGCTTTATACGCTGTGGTTGCCGCTGCTGAGCGCGGTGATGGGGCTGCGGGTTCTTGGTCGGTTGAGCCGT
TTGGCCCGGGGGACGCGATA

Downstream 100 bases:

>100_bases
GTCCGCGCCCGAGGGCGGCCCTTGTCGGTCCCCCTCGGACGAAGGCCTTGGTTTTAATGGCCGAGGAACACCGGCAGGGT
CATCTGGCGCAGGATGTCGC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MATLSLFAVFLGLTLLGAPLAVALGLAGSVAILEAQLGILSVPTTVYAGIAKYPLLAIPVFILAGLIFERVGVARQLVSF
ASSIVGARNGGLAIVAVLVCMVMGGISGSGPADAAAVATVMIPSLHKAGYPKAFSASVIAAGAATAILIPPSVAFIIYSV
LVPQASVPALFAGGLIPGLLAGLSLLAPIVYLSRRHGFGMADSGPRPGFWVSLKGAIWGLLAPVIILGGLRLGLFTPTEA
AVVAVFYGLFVGVFILRTLSGRMLIDMLADAAEMSGVVLLIIALASVFAWAGSTLGAFDAVAGAALQATDNEVVVLLMLN
LLLLGLGMVLDAVSIFLILLPLLVPFMEAFHWDPVWFGVMVTMNLAVGQFTPPMAVNLMVTTRIAGVRMEAATGWTLWFV
GAMIVALMVVTFVPELTLWLPRALGYL

Sequences:

>Translated_427_residues
MATLSLFAVFLGLTLLGAPLAVALGLAGSVAILEAQLGILSVPTTVYAGIAKYPLLAIPVFILAGLIFERVGVARQLVSF
ASSIVGARNGGLAIVAVLVCMVMGGISGSGPADAAAVATVMIPSLHKAGYPKAFSASVIAAGAATAILIPPSVAFIIYSV
LVPQASVPALFAGGLIPGLLAGLSLLAPIVYLSRRHGFGMADSGPRPGFWVSLKGAIWGLLAPVIILGGLRLGLFTPTEA
AVVAVFYGLFVGVFILRTLSGRMLIDMLADAAEMSGVVLLIIALASVFAWAGSTLGAFDAVAGAALQATDNEVVVLLMLN
LLLLGLGMVLDAVSIFLILLPLLVPFMEAFHWDPVWFGVMVTMNLAVGQFTPPMAVNLMVTTRIAGVRMEAATGWTLWFV
GAMIVALMVVTFVPELTLWLPRALGYL
>Mature_426_residues
ATLSLFAVFLGLTLLGAPLAVALGLAGSVAILEAQLGILSVPTTVYAGIAKYPLLAIPVFILAGLIFERVGVARQLVSFA
SSIVGARNGGLAIVAVLVCMVMGGISGSGPADAAAVATVMIPSLHKAGYPKAFSASVIAAGAATAILIPPSVAFIIYSVL
VPQASVPALFAGGLIPGLLAGLSLLAPIVYLSRRHGFGMADSGPRPGFWVSLKGAIWGLLAPVIILGGLRLGLFTPTEAA
VVAVFYGLFVGVFILRTLSGRMLIDMLADAAEMSGVVLLIIALASVFAWAGSTLGAFDAVAGAALQATDNEVVVLLMLNL
LLLGLGMVLDAVSIFLILLPLLVPFMEAFHWDPVWFGVMVTMNLAVGQFTPPMAVNLMVTTRIAGVRMEAATGWTLWFVG
AMIVALMVVTFVPELTLWLPRALGYL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=394, Percent_Identity=35.7868020304569, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44051; Mature: 43920

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLSLFAVFLGLTLLGAPLAVALGLAGSVAILEAQLGILSVPTTVYAGIAKYPLLAIPV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHH
FILAGLIFERVGVARQLVSFASSIVGARNGGLAIVAVLVCMVMGGISGSGPADAAAVATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MIPSLHKAGYPKAFSASVIAAGAATAILIPPSVAFIIYSVLVPQASVPALFAGGLIPGLL
HHHHHHHCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AGLSLLAPIVYLSRRHGFGMADSGPRPGFWVSLKGAIWGLLAPVIILGGLRLGLFTPTEA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCCCHHH
AVVAVFYGLFVGVFILRTLSGRMLIDMLADAAEMSGVVLLIIALASVFAWAGSTLGAFDA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VAGAALQATDNEVVVLLMLNLLLLGLGMVLDAVSIFLILLPLLVPFMEAFHWDPVWFGVM
HHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VTMNLAVGQFTPPMAVNLMVTTRIAGVRMEAATGWTLWFVGAMIVALMVVTFVPELTLWL
HHHHHHHCCCCCCCEEEEEEEHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGYL
HHHHCCC
>Mature Secondary Structure 
ATLSLFAVFLGLTLLGAPLAVALGLAGSVAILEAQLGILSVPTTVYAGIAKYPLLAIPV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHH
FILAGLIFERVGVARQLVSFASSIVGARNGGLAIVAVLVCMVMGGISGSGPADAAAVATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MIPSLHKAGYPKAFSASVIAAGAATAILIPPSVAFIIYSVLVPQASVPALFAGGLIPGLL
HHHHHHHCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AGLSLLAPIVYLSRRHGFGMADSGPRPGFWVSLKGAIWGLLAPVIILGGLRLGLFTPTEA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCCCHHH
AVVAVFYGLFVGVFILRTLSGRMLIDMLADAAEMSGVVLLIIALASVFAWAGSTLGAFDA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VAGAALQATDNEVVVLLMLNLLLLGLGMVLDAVSIFLILLPLLVPFMEAFHWDPVWFGVM
HHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VTMNLAVGQFTPPMAVNLMVTTRIAGVRMEAATGWTLWFVGAMIVALMVVTFVPELTLWL
HHHHHHHCCCCCCCEEEEEEEHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGYL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]