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The map label for this gene is rbsR [H]

Identifier: 83593308

GI number: 83593308

Start: 2282977

End: 2284002

Strand: Direct

Name: rbsR [H]

Synonym: Rru_A1973

Alternate gene names: 83593308

Gene position: 2282977-2284002 (Clockwise)

Preceding gene: 83593304

Following gene: 83593315

Centisome position: 52.45

GC content: 68.13

Gene sequence:

>1026_bases
ATGGATGACAATGATGCGAAACCGATGACCGTCAGCATCAAGGATGTCGCCCGCCATGCCGGGGTCTCGCCCTCGACGGT
GTCGCGCGCCCTGGGTCGCGGGCCGATCAGCGAGCCTTTGCGCCAGCAAGTCGAGGCCGCCGTCCGTGAAACCGGGTATC
GGCCCAATCTTTCGGCGCGGCGCTTGCGCTCACGCGAGAGCGGAACCGTCGGCCTGATCCTGGCCGATATCGGTAACCCC
TTTTTCACCGCCCTGACGCGGGCGGTGGAAGACGCCGCCTATCAGGCGGGGCTGCGGGTGATCTTGTGCAATACCGGCGA
AGACGCCGAGCGCGAGGCGATGTATCTGCGGCTGATGCAGGAAGAGCGGGTGAGCGGGGTGATCTTCGCCCCGACCCTGG
CCTATCTCGACCACCCGCCGCAGTCCCCCCTGGATTTTCCCGTCGTTCTTGTCGACCGCGCCGGGCCCCAGGGCCTTTAT
GACAGCGTCGTGCTCGACAACGAGGCCGCCTGCGCCACCCTGGTCGATCATTTCCACGCTCGCGGCTATCGGCGCATCAA
TGGGCTGTTTGGCAAGACCAGCGCCACCGGCGTCGAACGCCGCCGGGGCTATGACGACACCATGCGGGCTTACGGCCTGG
AGCCCAAAGCCTGCGCCATCGCCCCCCATGCCGAAGCCGCCGAGGTCGCCGTCAGCCGCTGGCTGAGCGAGCCCGAGCCG
CCCGAGGCGATCGTCGCCAGCAACAGCCTGCTGCTGATCGGCGCCCTGCGCGCCGTCCGCCGCGCCTGGCTGCGCCTGCC
CGACGACATCGCCCTCGCCGGCTTCGATAACGAGCTGTGGACCGAACTGGTCGAACCGGGAATGACGGTGATCGAACAGC
CGATCGAAGCCATCGGCCGCGCCGCCATGTCCCTGCTGCGCGACCGCATGGCCGATCCCACCCTGCCCCCCCGGCAGATC
GTGCTCAAGGGCCGGGCGATCATCCGCGGCTCAAGCGCCCCCGCCTTGGACGAGCGGAGTTTTTAG

Upstream 100 bases:

>100_bases
AAACGATTTCACAAATTTTGTCAAAAACCAATTCGGAGAAGATATAAATCTTCCTTATCCTTCCCATCTCAAGGGGCTAG
GTTAAAAAGAAGGGGGGACC

Downstream 100 bases:

>100_bases
TTAAAAAATTGGGGCCCGCTTTATGACTCACTCCGCACTGTTCTCGAATCCATAAAATGGCGGTCCCCGCATCACCCCCG
GTTCAAGTCCACCCCAGCAA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MDDNDAKPMTVSIKDVARHAGVSPSTVSRALGRGPISEPLRQQVEAAVRETGYRPNLSARRLRSRESGTVGLILADIGNP
FFTALTRAVEDAAYQAGLRVILCNTGEDAEREAMYLRLMQEERVSGVIFAPTLAYLDHPPQSPLDFPVVLVDRAGPQGLY
DSVVLDNEAACATLVDHFHARGYRRINGLFGKTSATGVERRRGYDDTMRAYGLEPKACAIAPHAEAAEVAVSRWLSEPEP
PEAIVASNSLLLIGALRAVRRAWLRLPDDIALAGFDNELWTELVEPGMTVIEQPIEAIGRAAMSLLRDRMADPTLPPRQI
VLKGRAIIRGSSAPALDERSF

Sequences:

>Translated_341_residues
MDDNDAKPMTVSIKDVARHAGVSPSTVSRALGRGPISEPLRQQVEAAVRETGYRPNLSARRLRSRESGTVGLILADIGNP
FFTALTRAVEDAAYQAGLRVILCNTGEDAEREAMYLRLMQEERVSGVIFAPTLAYLDHPPQSPLDFPVVLVDRAGPQGLY
DSVVLDNEAACATLVDHFHARGYRRINGLFGKTSATGVERRRGYDDTMRAYGLEPKACAIAPHAEAAEVAVSRWLSEPEP
PEAIVASNSLLLIGALRAVRRAWLRLPDDIALAGFDNELWTELVEPGMTVIEQPIEAIGRAAMSLLRDRMADPTLPPRQI
VLKGRAIIRGSSAPALDERSF
>Mature_341_residues
MDDNDAKPMTVSIKDVARHAGVSPSTVSRALGRGPISEPLRQQVEAAVRETGYRPNLSARRLRSRESGTVGLILADIGNP
FFTALTRAVEDAAYQAGLRVILCNTGEDAEREAMYLRLMQEERVSGVIFAPTLAYLDHPPQSPLDFPVVLVDRAGPQGLY
DSVVLDNEAACATLVDHFHARGYRRINGLFGKTSATGVERRRGYDDTMRAYGLEPKACAIAPHAEAAEVAVSRWLSEPEP
PEAIVASNSLLLIGALRAVRRAWLRLPDDIALAGFDNELWTELVEPGMTVIEQPIEAIGRAAMSLLRDRMADPTLPPRQI
VLKGRAIIRGSSAPALDERSF

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=30.5810397553517, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=31.7365269461078, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=29.0419161676647, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=28.9473684210526, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=30.2405498281787, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787906, Length=340, Percent_Identity=30, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=28.0130293159609, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=28.8888888888889, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=27.8125, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786540, Length=310, Percent_Identity=26.7741935483871, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786268, Length=303, Percent_Identity=26.7326732673267, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790689, Length=319, Percent_Identity=24.7648902821317, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790715, Length=336, Percent_Identity=23.5119047619048, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=22.9411764705882, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37185; Mature: 37185

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNDAKPMTVSIKDVARHAGVSPSTVSRALGRGPISEPLRQQVEAAVRETGYRPNLSAR
CCCCCCCCEEEEHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
RLRSRESGTVGLILADIGNPFFTALTRAVEDAAYQAGLRVILCNTGEDAEREAMYLRLMQ
HHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
EERVSGVIFAPTLAYLDHPPQSPLDFPVVLVDRAGPQGLYDSVVLDNEAACATLVDHFHA
HHHCCCEEEECHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCHHHHHHHHHHHH
RGYRRINGLFGKTSATGVERRRGYDDTMRAYGLEPKACAIAPHAEAAEVAVSRWLSEPEP
CCHHHHHHHCCCCCCCHHHHHCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCC
PEAIVASNSLLLIGALRAVRRAWLRLPDDIALAGFDNELWTELVEPGMTVIEQPIEAIGR
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHH
AAMSLLRDRMADPTLPPRQIVLKGRAIIRGSSAPALDERSF
HHHHHHHHHHCCCCCCHHHHEEECCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDDNDAKPMTVSIKDVARHAGVSPSTVSRALGRGPISEPLRQQVEAAVRETGYRPNLSAR
CCCCCCCCEEEEHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
RLRSRESGTVGLILADIGNPFFTALTRAVEDAAYQAGLRVILCNTGEDAEREAMYLRLMQ
HHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
EERVSGVIFAPTLAYLDHPPQSPLDFPVVLVDRAGPQGLYDSVVLDNEAACATLVDHFHA
HHHCCCEEEECHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCHHHHHHHHHHHH
RGYRRINGLFGKTSATGVERRRGYDDTMRAYGLEPKACAIAPHAEAAEVAVSRWLSEPEP
CCHHHHHHHCCCCCCCHHHHHCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCC
PEAIVASNSLLLIGALRAVRRAWLRLPDDIALAGFDNELWTELVEPGMTVIEQPIEAIGR
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHH
AAMSLLRDRMADPTLPPRQIVLKGRAIIRGSSAPALDERSF
HHHHHHHHHHCCCCCCHHHHEEECCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]