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The map label for this gene is nuoD

Identifier: 83592893

GI number: 83592893

Start: 1837792

End: 1838970

Strand: Direct

Name: nuoD

Synonym: Rru_A1558

Alternate gene names: 83592893

Gene position: 1837792-1838970 (Clockwise)

Preceding gene: 83592892

Following gene: 83592894

Centisome position: 42.22

GC content: 62.09

Gene sequence:

>1179_bases
ATGGCCCAGACCGAGATCAAATCCTATACCCTGAACTTCGGCCCCCAGCATCCGGCCGCCCATGGCGTGCTGCGCCTGGT
GCTCGAGCTGTCGGGCGAGGTGATCGAGCGCGCCGATCCCCATATCGGCCTGTTGCACCGGGGCACCGAGAAGCTGATCG
AATACAAGACCTATCTCCAGGCCTTGCCCTATTTCGATCGCCTCGATTACGCCTGTCCGATGAACCAGGAGCACGCCTAT
GTGCTCGCCGTCGAAAAGCTGCTGGGCATCACCGTGCCGCCCAGGGCCCAGTATCTGCGCACCTTGTTCAACGAGGTGAC
GCGGCTGATCAATCACATCATGAACACCACCTCGATGGCGCTCGACATCGGGGCGATGACGCCGCTGCTCTATGGCTTCG
AGGAACGCGAGCATCTGCTGGAGTTTTCCGAGCGCGCCTCGGGGGCGCGCATGCATGCGGCGTGGTTCCGCCCCGGCGGC
GTCGCCCGCGATGTGCCGCCCGATCTGCTCGAAGACATCCTGAAATTCTGCGACAGCTTCCCCAAATACCTCGACGACGT
CGAGCATCTGCTTGATGAAAACCGCATCTTCAAGCAGCGCACCGTCGATATCGGCAAGGTGACGGCCCAGCAGGCCCTGG
ATTGGGGCTTCACCGGGCCGGTGTTGCGCGGCTGCGGCGTGCCCTGGGACCTGCGCAAATCCCAGCCCTATGACGCCTAT
GCCGCCATGGATTTCGATATCCCGACGGGCGCCAACGGCGATTGCTATGACCGCTATCTGGTGCGCATGGCCGAGCAGCG
CCAAAGCATCCGCATCATGCGCCAATGCATCGAGAAGATGCCCGATGGTCCGGTCAAGGCGGTCGATCACAAGGTCACGC
CGCCGTCGCGCGGCGAGATGAAGTCGTCGATGGAAGCCTTGATCCATCACTTCAAGCTGTTTACCGAAGGCTTCAAGGTG
CCCGAGGGCGAGACCTATACGGCGGTCGAGGCCGCCACCGGCGAATTCGGCGTCTATCTGGTGTCCGATGGCACCAACCG
GCCCTATCGCTGCAAGATCCGCTCGCCGGGCTATGTCCATCTGCAGGGTCTCGATTTGATGAGCCGGGGCCATATGCTGG
CCGACGTGGTGGCCAACATCGGGTCCATCGACGTGGTGTTTGGAGAAATCGATCGATGA

Upstream 100 bases:

>100_bases
AGGATTTCCGCACCTTCGATTTCCTCAGCCCCTGGGAGGGGATGGACCGCCAGATCCGGCGGGTGCTGCCCGGCGACGAG
AAGGCCGAGGGGAACGCGTG

Downstream 100 bases:

>100_bases
GCGGCAACGGCGCTGCCGGCGAGCAGCCGGCGACCTTCGCGTTCACCCCCGAGAACCTGGAAAAGGCCCAGGCCATCTTG
GCCAAATATCCCAAGGGCCG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYACPMNQEHAY
VLAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMALDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGG
VARDVPPDLLEDILKFCDSFPKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAY
AAMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEMKSSMEALIHHFKLFTEGFKV
PEGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVHLQGLDLMSRGHMLADVVANIGSIDVVFGEIDR

Sequences:

>Translated_392_residues
MAQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYACPMNQEHAY
VLAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMALDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGG
VARDVPPDLLEDILKFCDSFPKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAY
AAMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEMKSSMEALIHHFKLFTEGFKV
PEGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVHLQGLDLMSRGHMLADVVANIGSIDVVFGEIDR
>Mature_391_residues
AQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYACPMNQEHAYV
LAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMALDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGGV
ARDVPPDLLEDILKFCDSFPKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAYA
AMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEMKSSMEALIHHFKLFTEGFKVP
EGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVHLQGLDLMSRGHMLADVVANIGSIDVVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=389, Percent_Identity=66.8380462724936, Blast_Score=550, Evalue=1e-156,
Organism=Homo sapiens, GI260898743, Length=383, Percent_Identity=66.3185378590078, Blast_Score=535, Evalue=1e-152,
Organism=Escherichia coli, GI145693162, Length=383, Percent_Identity=40.9921671018277, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1789076, Length=387, Percent_Identity=25.8397932816537, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788832, Length=381, Percent_Identity=27.0341207349081, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555284, Length=390, Percent_Identity=62.3076923076923, Blast_Score=525, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17568379, Length=390, Percent_Identity=61.7948717948718, Blast_Score=521, Evalue=1e-148,
Organism=Drosophila melanogaster, GI24638644, Length=390, Percent_Identity=65.3846153846154, Blast_Score=550, Evalue=1e-157,
Organism=Drosophila melanogaster, GI221459469, Length=387, Percent_Identity=61.4987080103359, Blast_Score=509, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_RHORT (Q2RU37)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426645.1
- HSSP:   Q56220
- ProteinModelPortal:   Q2RU37
- SMR:   Q2RU37
- STRING:   Q2RU37
- GeneID:   3834975
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1558
- NMPDR:   fig|1085.1.peg.2809
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   MADVITI
- PhylomeDB:   Q2RU37
- ProtClustDB:   PRK06075
- BioCyc:   RRUB269796:RRU_A1558-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 44279; Mature: 44148

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQ
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
ALPYFDRLDYACPMNQEHAYVLAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMA
HCCHHHHCCCCCCCCCCCHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGGVARDVPPDLLEDILKFCDSF
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
PKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCE
AAMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEM
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHH
KSSMEALIHHFKLFTEGFKVPEGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVH
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECCCCEEE
LQGLDLMSRGHMLADVVANIGSIDVVFGEIDR
EECCHHHHCCHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
AQTEIKSYTLNFGPQHPAAHGVLRLVLELSGEVIERADPHIGLLHRGTEKLIEYKTYLQ
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
ALPYFDRLDYACPMNQEHAYVLAVEKLLGITVPPRAQYLRTLFNEVTRLINHIMNTTSMA
HCCHHHHCCCCCCCCCCCHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDIGAMTPLLYGFEEREHLLEFSERASGARMHAAWFRPGGVARDVPPDLLEDILKFCDSF
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
PKYLDDVEHLLDENRIFKQRTVDIGKVTAQQALDWGFTGPVLRGCGVPWDLRKSQPYDAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCE
AAMDFDIPTGANGDCYDRYLVRMAEQRQSIRIMRQCIEKMPDGPVKAVDHKVTPPSRGEM
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHH
KSSMEALIHHFKLFTEGFKVPEGETYTAVEAATGEFGVYLVSDGTNRPYRCKIRSPGYVH
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEECCCCEEE
LQGLDLMSRGHMLADVVANIGSIDVVFGEIDR
EECCHHHHCCHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA