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The map label for this gene is nuoE [H]

Identifier: 83592894

GI number: 83592894

Start: 1838967

End: 1839593

Strand: Direct

Name: nuoE [H]

Synonym: Rru_A1559

Alternate gene names: 83592894

Gene position: 1838967-1839593 (Clockwise)

Preceding gene: 83592893

Following gene: 83592895

Centisome position: 42.25

GC content: 65.55

Gene sequence:

>627_bases
ATGAGCGGCAACGGCGCTGCCGGCGAGCAGCCGGCGACCTTCGCGTTCACCCCCGAGAACCTGGAAAAGGCCCAGGCCAT
CTTGGCCAAATATCCCAAGGGCCGGGAAAGAAGCGGCGTTTTGCCGTTGCTCGATCTCGCCCAGCGTCAGCAGGGCTGGG
TCAGCCACGCCGCCATCGAAGAGGTCGGCCGTTTAACCGGAACGCCGCGCATGCGGGTGCTCGAGGTCGCCACCTTCTAT
ACCATGTACAAGCTGTCGCCGAAGGGCCGCCACCACATCGAGGTCTGCACCAATCTGCCGTGCTGGCTGCGCGGATCCGA
CGAGATCCTGCGCGCCGTGCGCGACGAACTGGGCATCGAGGTTGGCGGCGAGACCGATGACGGGCTGTTCTCGCTGGCCG
AGGCGGAATGCCTGGGCGCCTGCGTCAACGCTCCCATGCTCCAGATCGGCGATGATTACTATGAAGACCTGACCTATGAG
AGCGTGCGCGAACTGGTGCGCAAGCTCAAGGTCGGCGAGCCGGTGACGCCGGGCTCGCAATCGGGTCGCCAGGGGGCTTG
CCCCGAGGGTGGGCCGACGACCCTGAAAAGTTTCTGTACCGCCGATAAGGCCGGGGGGAGCGTGTGA

Upstream 100 bases:

>100_bases
TCCATCTGCAGGGTCTCGATTTGATGAGCCGGGGCCATATGCTGGCCGACGTGGTGGCCAACATCGGGTCCATCGACGTG
GTGTTTGGAGAAATCGATCG

Downstream 100 bases:

>100_bases
TGCTGAACGATAAGGACCGCATCTTCACCAACCTCTACGGCTTTCAGGACTGGCGTCTGGCCGGGGCGCGCAAGCGCGGC
GATTGGGATGGCACCGGCGC

Product: NADH dehydrogenase (ubiquinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSGNGAAGEQPATFAFTPENLEKAQAILAKYPKGRERSGVLPLLDLAQRQQGWVSHAAIEEVGRLTGTPRMRVLEVATFY
TMYKLSPKGRHHIEVCTNLPCWLRGSDEILRAVRDELGIEVGGETDDGLFSLAEAECLGACVNAPMLQIGDDYYEDLTYE
SVRELVRKLKVGEPVTPGSQSGRQGACPEGGPTTLKSFCTADKAGGSV

Sequences:

>Translated_208_residues
MSGNGAAGEQPATFAFTPENLEKAQAILAKYPKGRERSGVLPLLDLAQRQQGWVSHAAIEEVGRLTGTPRMRVLEVATFY
TMYKLSPKGRHHIEVCTNLPCWLRGSDEILRAVRDELGIEVGGETDDGLFSLAEAECLGACVNAPMLQIGDDYYEDLTYE
SVRELVRKLKVGEPVTPGSQSGRQGACPEGGPTTLKSFCTADKAGGSV
>Mature_207_residues
SGNGAAGEQPATFAFTPENLEKAQAILAKYPKGRERSGVLPLLDLAQRQQGWVSHAAIEEVGRLTGTPRMRVLEVATFYT
MYKLSPKGRHHIEVCTNLPCWLRGSDEILRAVRDELGIEVGGETDDGLFSLAEAECLGACVNAPMLQIGDDYYEDLTYES
VRELVRKLKVGEPVTPGSQSGRQGACPEGGPTTLKSFCTADKAGGSV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=182, Percent_Identity=54.3956043956044, Blast_Score=213, Evalue=9e-56,
Organism=Escherichia coli, GI1788621, Length=163, Percent_Identity=33.1288343558282, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561328, Length=183, Percent_Identity=51.3661202185792, Blast_Score=200, Evalue=4e-52,
Organism=Drosophila melanogaster, GI18859877, Length=182, Percent_Identity=51.6483516483517, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI21355353, Length=183, Percent_Identity=43.1693989071038, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22416; Mature: 22284

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNGAAGEQPATFAFTPENLEKAQAILAKYPKGRERSGVLPLLDLAQRQQGWVSHAAIE
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EVGRLTGTPRMRVLEVATFYTMYKLSPKGRHHIEVCTNLPCWLRGSDEILRAVRDELGIE
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHCCCCCCEECCCHHHHHHHHHHHCEE
VGGETDDGLFSLAEAECLGACVNAPMLQIGDDYYEDLTYESVRELVRKLKVGEPVTPGSQ
ECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
SGRQGACPEGGPTTLKSFCTADKAGGSV
CCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGNGAAGEQPATFAFTPENLEKAQAILAKYPKGRERSGVLPLLDLAQRQQGWVSHAAIE
CCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EVGRLTGTPRMRVLEVATFYTMYKLSPKGRHHIEVCTNLPCWLRGSDEILRAVRDELGIE
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHCCCCCCEECCCHHHHHHHHHHHCEE
VGGETDDGLFSLAEAECLGACVNAPMLQIGDDYYEDLTYESVRELVRKLKVGEPVTPGSQ
ECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
SGRQGACPEGGPTTLKSFCTADKAGGSV
CCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA