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The map label for this gene is nuoC

Identifier: 83592892

GI number: 83592892

Start: 1837151

End: 1837792

Strand: Direct

Name: nuoC

Synonym: Rru_A1557

Alternate gene names: 83592892

Gene position: 1837151-1837792 (Clockwise)

Preceding gene: 83592891

Following gene: 83592893

Centisome position: 42.21

GC content: 63.08

Gene sequence:

>642_bases
ATGACGAGTGTTTTCGAAGAACGGGTCGAGAGCCTCAAGGAACTTGGGGCCCGCATCGAAGCCGCCCTGCCGACCGACGT
GGTCCGCGTCGAGATGGCCAAGGACGAGCTTCAGGTGATCGCCCAGCGGCCATCGATCGCCAAGGTCCTGACGTTCCTGC
GCGATGACAGCGCCTGTCGCTTCAGTCAGCTGGTCGATATCGCCGGCGTCGACTACCCCAGCCGCGAAGAGCGGTTCGAG
GTGGTCTATAACATGCTGTCGATGCACCATAATCAGCGGATCCGGGTGAAGATCTCGGCAAGCGAGGACACCCCCGTTCC
GTCGGTGACCCGGGTGTTCTCCTCGGCTAATTGGTTCGAGCGCGAAGCCTGGGACATGTACGGGATCTTCTTTTCCGAGC
ATCCCGACCTGCGGCGGCTGTTGTCGGACTACGGCTTTGAGGGCCATGCCCAGCGCAAGGACTTCCCGCTGACCGGCTAT
AAAGAGGTGCGCTACGACGAGGAGCTCAAGCGGGTGGTCTACGAGCCCGTGCGCCTGAGCCAGGATTTCCGCACCTTCGA
TTTCCTCAGCCCCTGGGAGGGGATGGACCGCCAGATCCGGCGGGTGCTGCCCGGCGACGAGAAGGCCGAGGGGAACGCGT
GA

Upstream 100 bases:

>100_bases
CTGCTGTACGGGGTGTTGCAGCTGCAAAAGAAGATCAAGCGGACCGGCGCGCTTTACCGGTGACCGGTCGGCAACGCCTT
AGAGTGGGGAACGGCGCGGA

Downstream 100 bases:

>100_bases
TGGCCCAGACCGAGATCAAATCCTATACCCTGAACTTCGGCCCCCAGCATCCGGCCGCCCATGGCGTGCTGCGCCTGGTG
CTCGAGCTGTCGGGCGAGGT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACRFSQLVDIAGVDYPSREERFE
VVYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFEREAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGY
KEVRYDEELKRVVYEPVRLSQDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA

Sequences:

>Translated_213_residues
MTSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACRFSQLVDIAGVDYPSREERFE
VVYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFEREAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGY
KEVRYDEELKRVVYEPVRLSQDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA
>Mature_212_residues
TSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACRFSQLVDIAGVDYPSREERFEV
VYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFEREAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGYK
EVRYDEELKRVVYEPVRLSQDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=187, Percent_Identity=53.475935828877, Blast_Score=214, Evalue=4e-56,
Organism=Escherichia coli, GI145693162, Length=104, Percent_Identity=39.4230769230769, Blast_Score=87, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=189, Percent_Identity=49.2063492063492, Blast_Score=202, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI32563621, Length=189, Percent_Identity=49.2063492063492, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=55.7377049180328, Blast_Score=220, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_RHORT (Q2RU38)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426644.1
- ProteinModelPortal:   Q2RU38
- SMR:   Q2RU38
- STRING:   Q2RU38
- GeneID:   3834974
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1557
- NMPDR:   fig|1085.1.peg.2810
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   RRUB269796:RRU_A1557-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 24847; Mature: 24716

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACR
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
FSQLVDIAGVDYPSREERFEVVYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHH
REAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGYKEVRYDEELKRVVYEPVRLS
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
QDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA
CCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSVFEERVESLKELGARIEAALPTDVVRVEMAKDELQVIAQRPSIAKVLTFLRDDSACR
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
FSQLVDIAGVDYPSREERFEVVYNMLSMHHNQRIRVKISASEDTPVPSVTRVFSSANWFE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCHHH
REAWDMYGIFFSEHPDLRRLLSDYGFEGHAQRKDFPLTGYKEVRYDEELKRVVYEPVRLS
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
QDFRTFDFLSPWEGMDRQIRRVLPGDEKAEGNA
CCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA