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The map label for this gene is galE [H]

Identifier: 83592822

GI number: 83592822

Start: 1754891

End: 1755856

Strand: Reverse

Name: galE [H]

Synonym: Rru_A1486

Alternate gene names: 83592822

Gene position: 1755856-1754891 (Counterclockwise)

Preceding gene: 83592823

Following gene: 83592821

Centisome position: 40.34

GC content: 70.7

Gene sequence:

>966_bases
ATGGATGGCTGCGTTCTGGTGACCGGCGGCGCCGGTTTCATCGGCAGTCGGGTTGTCGCCGGACTGCGGGCGGCGGGAAG
CCGCGTCGCCGTTCTTGACGACGCCTCGGCCGGCCGGCCGTTACCCGCCCGCACCGAAGGACTGGAGGTGATCGCCGGCG
ATATCCGCGACGCCGATCTTACGGGGCGGGTCGTCGCCGCCCTGCGTCCGGCCGCCATCGTCCATCTCGCCGCCCTTCAC
CACATTCCAAGCTGCACCAAAGATCCCCGCCGCGCCCTCGATATCAACGTCGTCGGCACCCAGTCGGTGCTTGACGCGGC
GGCGGCGGCGGGCGTCGCGCGGGTGGTCATCGCCTCGTCGGGGGCGGTTTATGACTGGGGCGTCGGCGCTTTGAGCGAGG
AAAGCCCGACCTCCCCCCACGATATCTACGCTCTGAGCAAACTGACCAACGAGCACCAACTGGCGCTCTGGGCGCGCCAG
CCCGGACGCTGGGCCCGGGTGGCCCGGCTGTTCAACGTCATCGGCCCAGGGGATCCGAACGGCCATCTCATCCCCGAGGT
TCTCGACCGTCTGGCCGGCGCGGCCGACACCGCGCGCGCGGCCGATCCCATTGTCCTGCGGCTTGGCCATCTTGACCACC
GCCGCGATTATATCGCCCTGGAGGATGCCGCCGAGGGGCTGATCGCCCTGCTGGGCGATGGCGATCCGGCGCCGTTTTCC
ATCGACAATCTGTGCAGCGGCCGCGAACTCGGCGTCGAGGATCTGGTCACCCGGTTGGCCGATCTGCTGGGCCTTCGCAT
CACCTGCCTGTCCGATCCGGCCCTGCGCCGCCCCAACGACCGCCCCTCGCAGCTTGGCGCGCCGGAACGGGCCTGGCGGC
GCCTGGGGTGGCGGGTGCGCCGGCCGGTGGACAGCGCCTTGGCCGAGATCGCCGCCGCCGACGGCCGCTTCGCCCTGGTA
TCATGA

Upstream 100 bases:

>100_bases
GCCGAGGAATATACCCCGGTGCAGCCGGGCGATATCGTCCGGGTGCTCGAGCGGCGCTTCTAGGACGGCGCCCGCCATGG
CCCCGCCCCTCCCCTCGCCC

Downstream 100 bases:

>100_bases
GGCTCGGCCGGCGCGCCCTGCTCGTGGCCGGTCTGGCGGGATGGCTGGGGGCCTGCGCCGGCCGGCCGGCGGCGGGCGCG
ATCGTCACCCCCCGTGACTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDGCVLVTGGAGFIGSRVVAGLRAAGSRVAVLDDASAGRPLPARTEGLEVIAGDIRDADLTGRVVAALRPAAIVHLAALH
HIPSCTKDPRRALDINVVGTQSVLDAAAAAGVARVVIASSGAVYDWGVGALSEESPTSPHDIYALSKLTNEHQLALWARQ
PGRWARVARLFNVIGPGDPNGHLIPEVLDRLAGAADTARAADPIVLRLGHLDHRRDYIALEDAAEGLIALLGDGDPAPFS
IDNLCSGRELGVEDLVTRLADLLGLRITCLSDPALRRPNDRPSQLGAPERAWRRLGWRVRRPVDSALAEIAAADGRFALV
S

Sequences:

>Translated_321_residues
MDGCVLVTGGAGFIGSRVVAGLRAAGSRVAVLDDASAGRPLPARTEGLEVIAGDIRDADLTGRVVAALRPAAIVHLAALH
HIPSCTKDPRRALDINVVGTQSVLDAAAAAGVARVVIASSGAVYDWGVGALSEESPTSPHDIYALSKLTNEHQLALWARQ
PGRWARVARLFNVIGPGDPNGHLIPEVLDRLAGAADTARAADPIVLRLGHLDHRRDYIALEDAAEGLIALLGDGDPAPFS
IDNLCSGRELGVEDLVTRLADLLGLRITCLSDPALRRPNDRPSQLGAPERAWRRLGWRVRRPVDSALAEIAAADGRFALV
S
>Mature_321_residues
MDGCVLVTGGAGFIGSRVVAGLRAAGSRVAVLDDASAGRPLPARTEGLEVIAGDIRDADLTGRVVAALRPAAIVHLAALH
HIPSCTKDPRRALDINVVGTQSVLDAAAAAGVARVVIASSGAVYDWGVGALSEESPTSPHDIYALSKLTNEHQLALWARQ
PGRWARVARLFNVIGPGDPNGHLIPEVLDRLAGAADTARAADPIVLRLGHLDHRRDYIALEDAAEGLIALLGDGDPAPFS
IDNLCSGRELGVEDLVTRLADLLGLRITCLSDPALRRPNDRPSQLGAPERAWRRLGWRVRRPVDSALAEIAAADGRFALV
S

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=322, Percent_Identity=27.639751552795, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI56237023, Length=329, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI56118217, Length=329, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI189083684, Length=329, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=322, Percent_Identity=29.8136645962733, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI48994969, Length=282, Percent_Identity=28.0141843971631, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=27.5964391691395, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=29.3768545994065, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356223, Length=319, Percent_Identity=26.0188087774295, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33748; Mature: 33748

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGCVLVTGGAGFIGSRVVAGLRAAGSRVAVLDDASAGRPLPARTEGLEVIAGDIRDADL
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGRVVAALRPAAIVHLAALHHIPSCTKDPRRALDINVVGTQSVLDAAAAAGVARVVIASS
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHEEEEECC
GAVYDWGVGALSEESPTSPHDIYALSKLTNEHQLALWARQPGRWARVARLFNVIGPGDPN
CCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCC
GHLIPEVLDRLAGAADTARAADPIVLRLGHLDHRRDYIALEDAAEGLIALLGDGDPAPFS
CCCHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCEEEHHHHHCCEEEEECCCCCCCCC
IDNLCSGRELGVEDLVTRLADLLGLRITCLSDPALRRPNDRPSQLGAPERAWRRLGWRVR
HHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCHHCCCCCCHHHCCCHHHHHHHHCCHHC
RPVDSALAEIAAADGRFALVS
CCHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MDGCVLVTGGAGFIGSRVVAGLRAAGSRVAVLDDASAGRPLPARTEGLEVIAGDIRDADL
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGRVVAALRPAAIVHLAALHHIPSCTKDPRRALDINVVGTQSVLDAAAAAGVARVVIASS
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHEEEEECC
GAVYDWGVGALSEESPTSPHDIYALSKLTNEHQLALWARQPGRWARVARLFNVIGPGDPN
CCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCC
GHLIPEVLDRLAGAADTARAADPIVLRLGHLDHRRDYIALEDAAEGLIALLGDGDPAPFS
CCCHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCEEEHHHHHCCEEEEECCCCCCCCC
IDNLCSGRELGVEDLVTRLADLLGLRITCLSDPALRRPNDRPSQLGAPERAWRRLGWRVR
HHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCHHCCCCCCHHHCCCHHHHHHHHCCHHC
RPVDSALAEIAAADGRFALVS
CCHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]