Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 83592479

GI number: 83592479

Start: 1349175

End: 1350665

Strand: Reverse

Name: mocR [H]

Synonym: Rru_A1143

Alternate gene names: 83592479

Gene position: 1350665-1349175 (Counterclockwise)

Preceding gene: 83592484

Following gene: 83592478

Centisome position: 31.03

GC content: 65.46

Gene sequence:

>1491_bases
TTGTTCAAGCATTCCCAACTGGATTCCGTAAAGGCATGGATTGCCCATCCCGCCCATGCGGTGATGCCGCTTCACGCGCG
GATTCAGCGGGCCATTCGGCAATTGATCGTCGACGGCGCGCTGGGAGCGGGCAAGCCGCTGCCCGCCTCGCGCGCCCTCG
CCACATCGCTTGGGGTATCGCGCGACACGATCGAAGCGGCCTATTCCCAACTTCATGCCGAGGGGTTCATCGACCGGCGC
GTGGGAAGCGGCAGCTTCGTGGCGGAAATGACCGAGTTCATGCCCAGCCGTCCCCTTTCCCAGCGGGATGCGCTCTTGCG
CAACCAAGCTCCCACTCTCAGCACCCGGGGGGCGGCCATGTTCCGCAGTGGCGGCGTTCGCGAGATGCTCGCCCCACGGC
CTTTCGCTCATGGGGTGCCGGAAACCCGAACCTTTCCCCTCCAACTCTGGGAACGTCTGGAACGGCAGGTGCGCAAGGAG
GTCGGCGCGCAAACCCTGTTTCATGGCGACCCGCAGGGGACCGAGGCGCTTCGCCGCGCCATCGCCGACTATGTGAACCT
GGAACGCGGCGCCCGCGCCACGGCCGACCGCGTGCTGGTGCTGACCAGTTCGCAACAGGCGATGTCGCTATGCGCGACCA
TGCTGCTTGATCCCGGCGACCGGATCTTCCTTGAAGACCCCGCCTATTACGGGGCGCGCAAGGCGTTCGATGCGGCGGGG
CTGGACTGCGTTCCGATCCCTGTCGACCGGCAAGGTATCGTGGTCGATCAAATCATGGCCGAACCGCACGGGGCCAAGGC
GGTTTTCCTGACGCCATCCCACCAGTTTCCGACCGGCGCGACGCTGGCGCTGGACCGCCGTCTGGCGCTGATCGAATGGG
CGGCGCGGACTCAGGCGTGGATCATCGAAGACGATTACGACAGCGAGTTCCACTACGCGGGCAAGCCGACGGCCTGCGTG
CAAGGTCTCGATAAGCATGACCGCACCCTCTACATCGGCACCTTCACCAAATCGCTCTTTCCGGGCTTGCGGATCGGCTA
TGTCGTCTTGCCCCCGCCGCTGGTGAAGCCGATGACCGTCGCCCGCACCTTGCTTGATGGCCATACGGCCCCCATGGCGC
AACTGACGCTGGCCCGCTTTATGGAAGGGGGGCATTTCGGGGCGTATGTTCGCACCATGCGCGGCGTCTATGCCGAGCGG
CTCGCCCTCCTGGCCGGCCTTGTCAGCAAGCATCTGGCGGATTTCGTCGAGCCGCGCGTTCCCATTGGCGGGCTGCAACT
GCCCTGTCTGTTGACCCGCGACCTCTCGGAACGCACCGCCATCGACGCGGCGCGACGGGTCGGGATCGAGTTGCTCGGCT
TGTCGGCGTTGCACGCCGCCGGCGATGGCAAAGCCGGCTTCCTGATGGGCTTTGCCGCCTATACGCCCCTCGAAATCGAG
GAGGCCGTGAGGAAACTGGAAAAGGCGCTGCGGGCGGTGACAAGGCCATAG

Upstream 100 bases:

>100_bases
CCCCTGAAGGTCTGAGCCGCAATGGCAATCAGTCGGCTTGACACTTAGCCGATGAATGGCCTGATATGCCCAGCCACTTT
TTTCGAGGGGACCAGACCAT

Downstream 100 bases:

>100_bases
GATACCCCCGCACGCCAGACATCAGACTGGACAGGACCATCGGACATGGCGCGCCTGCGGCGCAAATGGTCTGAATGATT
TGCTGAAAATGGCAGGGCTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MFKHSQLDSVKAWIAHPAHAVMPLHARIQRAIRQLIVDGALGAGKPLPASRALATSLGVSRDTIEAAYSQLHAEGFIDRR
VGSGSFVAEMTEFMPSRPLSQRDALLRNQAPTLSTRGAAMFRSGGVREMLAPRPFAHGVPETRTFPLQLWERLERQVRKE
VGAQTLFHGDPQGTEALRRAIADYVNLERGARATADRVLVLTSSQQAMSLCATMLLDPGDRIFLEDPAYYGARKAFDAAG
LDCVPIPVDRQGIVVDQIMAEPHGAKAVFLTPSHQFPTGATLALDRRLALIEWAARTQAWIIEDDYDSEFHYAGKPTACV
QGLDKHDRTLYIGTFTKSLFPGLRIGYVVLPPPLVKPMTVARTLLDGHTAPMAQLTLARFMEGGHFGAYVRTMRGVYAER
LALLAGLVSKHLADFVEPRVPIGGLQLPCLLTRDLSERTAIDAARRVGIELLGLSALHAAGDGKAGFLMGFAAYTPLEIE
EAVRKLEKALRAVTRP

Sequences:

>Translated_496_residues
MFKHSQLDSVKAWIAHPAHAVMPLHARIQRAIRQLIVDGALGAGKPLPASRALATSLGVSRDTIEAAYSQLHAEGFIDRR
VGSGSFVAEMTEFMPSRPLSQRDALLRNQAPTLSTRGAAMFRSGGVREMLAPRPFAHGVPETRTFPLQLWERLERQVRKE
VGAQTLFHGDPQGTEALRRAIADYVNLERGARATADRVLVLTSSQQAMSLCATMLLDPGDRIFLEDPAYYGARKAFDAAG
LDCVPIPVDRQGIVVDQIMAEPHGAKAVFLTPSHQFPTGATLALDRRLALIEWAARTQAWIIEDDYDSEFHYAGKPTACV
QGLDKHDRTLYIGTFTKSLFPGLRIGYVVLPPPLVKPMTVARTLLDGHTAPMAQLTLARFMEGGHFGAYVRTMRGVYAER
LALLAGLVSKHLADFVEPRVPIGGLQLPCLLTRDLSERTAIDAARRVGIELLGLSALHAAGDGKAGFLMGFAAYTPLEIE
EAVRKLEKALRAVTRP
>Mature_496_residues
MFKHSQLDSVKAWIAHPAHAVMPLHARIQRAIRQLIVDGALGAGKPLPASRALATSLGVSRDTIEAAYSQLHAEGFIDRR
VGSGSFVAEMTEFMPSRPLSQRDALLRNQAPTLSTRGAAMFRSGGVREMLAPRPFAHGVPETRTFPLQLWERLERQVRKE
VGAQTLFHGDPQGTEALRRAIADYVNLERGARATADRVLVLTSSQQAMSLCATMLLDPGDRIFLEDPAYYGARKAFDAAG
LDCVPIPVDRQGIVVDQIMAEPHGAKAVFLTPSHQFPTGATLALDRRLALIEWAARTQAWIIEDDYDSEFHYAGKPTACV
QGLDKHDRTLYIGTFTKSLFPGLRIGYVVLPPPLVKPMTVARTLLDGHTAPMAQLTLARFMEGGHFGAYVRTMRGVYAER
LALLAGLVSKHLADFVEPRVPIGGLQLPCLLTRDLSERTAIDAARRVGIELLGLSALHAAGDGKAGFLMGFAAYTPLEIE
EAVRKLEKALRAVTRP

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=315, Percent_Identity=24.7619047619048, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI33469970, Length=315, Percent_Identity=24.7619047619048, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1787710, Length=382, Percent_Identity=28.0104712041885, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1790797, Length=460, Percent_Identity=25.8695652173913, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54186; Mature: 54186

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKHSQLDSVKAWIAHPAHAVMPLHARIQRAIRQLIVDGALGAGKPLPASRALATSLGVS
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDTIEAAYSQLHAEGFIDRRVGSGSFVAEMTEFMPSRPLSQRDALLRNQAPTLSTRGAAM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHH
FRSGGVREMLAPRPFAHGVPETRTFPLQLWERLERQVRKEVGAQTLFHGDPQGTEALRRA
HHCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHH
IADYVNLERGARATADRVLVLTSSQQAMSLCATMLLDPGDRIFLEDPAYYGARKAFDAAG
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCC
LDCVPIPVDRQGIVVDQIMAEPHGAKAVFLTPSHQFPTGATLALDRRLALIEWAARTQAW
CCEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
IIEDDYDSEFHYAGKPTACVQGLDKHDRTLYIGTFTKSLFPGLRIGYVVLPPPLVKPMTV
EEECCCCCCCEECCCCHHHHHCCCCCCCEEEEEECHHHHCCCCEEEEEEECCCCCCHHHH
ARTLLDGHTAPMAQLTLARFMEGGHFGAYVRTMRGVYAERLALLAGLVSKHLADFVEPRV
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIGGLQLPCLLTRDLSERTAIDAARRVGIELLGLSALHAAGDGKAGFLMGFAAYTPLEIE
CCCCCCCCHHHHCCHHHHHHHHHHHHHCHHHCCHHHHHCCCCCCCHHHHHHHHCCCHHHH
EAVRKLEKALRAVTRP
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKHSQLDSVKAWIAHPAHAVMPLHARIQRAIRQLIVDGALGAGKPLPASRALATSLGVS
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDTIEAAYSQLHAEGFIDRRVGSGSFVAEMTEFMPSRPLSQRDALLRNQAPTLSTRGAAM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHH
FRSGGVREMLAPRPFAHGVPETRTFPLQLWERLERQVRKEVGAQTLFHGDPQGTEALRRA
HHCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHH
IADYVNLERGARATADRVLVLTSSQQAMSLCATMLLDPGDRIFLEDPAYYGARKAFDAAG
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCC
LDCVPIPVDRQGIVVDQIMAEPHGAKAVFLTPSHQFPTGATLALDRRLALIEWAARTQAW
CCEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
IIEDDYDSEFHYAGKPTACVQGLDKHDRTLYIGTFTKSLFPGLRIGYVVLPPPLVKPMTV
EEECCCCCCCEECCCCHHHHHCCCCCCCEEEEEECHHHHCCCCEEEEEEECCCCCCHHHH
ARTLLDGHTAPMAQLTLARFMEGGHFGAYVRTMRGVYAERLALLAGLVSKHLADFVEPRV
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIGGLQLPCLLTRDLSERTAIDAARRVGIELLGLSALHAAGDGKAGFLMGFAAYTPLEIE
CCCCCCCCHHHHCCHHHHHHHHHHHHHCHHHCCHHHHHCCCCCCCHHHHHHHHCCCHHHH
EAVRKLEKALRAVTRP
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]