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The map label for this gene is pabB [H]

Identifier: 83592468

GI number: 83592468

Start: 1333672

End: 1335096

Strand: Reverse

Name: pabB [H]

Synonym: Rru_A1132

Alternate gene names: 83592468

Gene position: 1335096-1333672 (Counterclockwise)

Preceding gene: 83592469

Following gene: 83592467

Centisome position: 30.67

GC content: 71.79

Gene sequence:

>1425_bases
TTGTCCCTTCATATCCGCCCCATCGCCTTTGCCGACCCGCTGACCCTGGTCCCGGCCTTGGCCAAGGATCCGGTCTTCGC
CTTTCTCGACAGCGCCGCCGCCGATCCCGGCGCGGGCGACGAGGATCGCGGCCGTTACAGCTATCTCTGCGCCGATCCCT
GGCGGGTGATCACCGCCGATGACACCACGGTCCGGGTCGATAGCCGGCCGGTCGCCGGCGATCCCTTCGCCGTTCTCGCC
GCCACCCTGGCCGAAATCGCCGAGGACGAGCCCGTCGCTTGCCCGGTGCCCTTCGCCACCGGCCTATGCGGTGTCCTTGG
TTACGGCCTGGGTGCTTGGCTGGAACGGCTGGCCCCCGCCCCGGCCGATCGGCTGGCCCTGCCGGCGATGACCCTGGGCG
TCTATGACTGCGTCGCCGCCTTCGACCTGCGCGCGCGCAAGGCCTGGATCGTTTCCAGCGGCCGGCCCGAACGCGATCCG
CGGCGCCGCGCCGCCCGCGCCCTGGCCCGCGCCGAAGCCCTGGAACGGCGCTTGGCCGCGGTTTCCCTTGTCCCTGACGA
GACCGCCGCCGCTTATGAAAAGACCGGGTCCTGGCGCGCCGAGCGACCGCGCGCGGCGATCTTGGCGGCGATCGGCAAGA
CCATCGACGCCATCGAAGCCGGCGAGCTGTTCCAGGCCAATATCACCCAGCGCTTCCTGGCCGACCTTCCGCCCGGCCTC
GACGACCTCACCTTGTATCGCCGCCTGCGCCGGCTGAGCCCGGCCCCCTTCGCCGCCCTGGTCGGCTGCGGCGCCGACCA
CCGCCTGATCGGCGCCTCGCCCGAACGCTTCTTGCGCCTGGGCGCCGAGGGCCGGGTCGAGACGCGGCCGATCAAGGGCA
CCCGCCGGCGCGACGCCGATCCGGCGCGCGACGCCGCCCAGGCCGCCGCTCTGGTGGCCAGCGAAAAGGACCGGGCCGAG
AACCTGATGATCGTCGATCTGATGCGCAACGACCTGGGCCGGGTCTGCGCCATCGGCAGCGTCCGTGTGCCCCGGCTGAT
CGCCCTGGAAAGCTTCGCCAGCGTCCACCATCTGGTCTCGGCGGTCGAAGGGCGGCTGCGCCCCGGCCTGGGGGCGATCG
ACCTGCTGCGCGCCTGTTTTCCCGGCGGCTCGGTCACCGGGGCGCCGAAGATCCGCGCCATGGACCTGATCACCGCCCTG
GAGCCGGCCCGGCGCGGCTGGTATTGCGGATCGGTGGCCTGGATCGGCGCCGATGGGGCGATGGATTCCAACATCGTCAT
CCGCAGCCTCACCCGGGCCGGTGCCACCCTGATCGCCCAGGCCGGCGGCGCCATCACCGCGCCCTCCGATCCGGCCGAGG
AATACGAGGAAAGCCTGATCAAAATGGCCCCCCTGCTCAGCGCCCTGGATGGGATCGAGCGATGA

Upstream 100 bases:

>100_bases
GAAGCCGCCATCCCCTTGCGCGCCGCCGTCGCCAAAGGCCGGGGGGCAGCGGCCAAGGGCCGTGGTCGCAAGGGCAAAAG
GTGAAAAGAAGCCGCAGCCC

Downstream 100 bases:

>100_bases
CCGCCCGGCGACCGGCCGTCATTTGGCTGAACGACCGGCTCGTGCCCGCCGCAAAGGCCCGCATCGATCCCGCCGATCGC
GGATTTCTGCTTGGCGATGG

Product: aminodeoxychorismate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSLHIRPIAFADPLTLVPALAKDPVFAFLDSAAADPGAGDEDRGRYSYLCADPWRVITADDTTVRVDSRPVAGDPFAVLA
ATLAEIAEDEPVACPVPFATGLCGVLGYGLGAWLERLAPAPADRLALPAMTLGVYDCVAAFDLRARKAWIVSSGRPERDP
RRRAARALARAEALERRLAAVSLVPDETAAAYEKTGSWRAERPRAAILAAIGKTIDAIEAGELFQANITQRFLADLPPGL
DDLTLYRRLRRLSPAPFAALVGCGADHRLIGASPERFLRLGAEGRVETRPIKGTRRRDADPARDAAQAAALVASEKDRAE
NLMIVDLMRNDLGRVCAIGSVRVPRLIALESFASVHHLVSAVEGRLRPGLGAIDLLRACFPGGSVTGAPKIRAMDLITAL
EPARRGWYCGSVAWIGADGAMDSNIVIRSLTRAGATLIAQAGGAITAPSDPAEEYEESLIKMAPLLSALDGIER

Sequences:

>Translated_474_residues
MSLHIRPIAFADPLTLVPALAKDPVFAFLDSAAADPGAGDEDRGRYSYLCADPWRVITADDTTVRVDSRPVAGDPFAVLA
ATLAEIAEDEPVACPVPFATGLCGVLGYGLGAWLERLAPAPADRLALPAMTLGVYDCVAAFDLRARKAWIVSSGRPERDP
RRRAARALARAEALERRLAAVSLVPDETAAAYEKTGSWRAERPRAAILAAIGKTIDAIEAGELFQANITQRFLADLPPGL
DDLTLYRRLRRLSPAPFAALVGCGADHRLIGASPERFLRLGAEGRVETRPIKGTRRRDADPARDAAQAAALVASEKDRAE
NLMIVDLMRNDLGRVCAIGSVRVPRLIALESFASVHHLVSAVEGRLRPGLGAIDLLRACFPGGSVTGAPKIRAMDLITAL
EPARRGWYCGSVAWIGADGAMDSNIVIRSLTRAGATLIAQAGGAITAPSDPAEEYEESLIKMAPLLSALDGIER
>Mature_473_residues
SLHIRPIAFADPLTLVPALAKDPVFAFLDSAAADPGAGDEDRGRYSYLCADPWRVITADDTTVRVDSRPVAGDPFAVLAA
TLAEIAEDEPVACPVPFATGLCGVLGYGLGAWLERLAPAPADRLALPAMTLGVYDCVAAFDLRARKAWIVSSGRPERDPR
RRAARALARAEALERRLAAVSLVPDETAAAYEKTGSWRAERPRAAILAAIGKTIDAIEAGELFQANITQRFLADLPPGLD
DLTLYRRLRRLSPAPFAALVGCGADHRLIGASPERFLRLGAEGRVETRPIKGTRRRDADPARDAAQAAALVASEKDRAEN
LMIVDLMRNDLGRVCAIGSVRVPRLIALESFASVHHLVSAVEGRLRPGLGAIDLLRACFPGGSVTGAPKIRAMDLITALE
PARRGWYCGSVAWIGADGAMDSNIVIRSLTRAGATLIAQAGGAITAPSDPAEEYEESLIKMAPLLSALDGIER

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=443, Percent_Identity=37.020316027088, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1787518, Length=374, Percent_Identity=32.0855614973262, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786809, Length=230, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082077, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=461, Percent_Identity=30.1518438177874, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=424, Percent_Identity=24.7641509433962, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50440; Mature: 50309

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHIRPIAFADPLTLVPALAKDPVFAFLDSAAADPGAGDEDRGRYSYLCADPWRVITAD
CCEEEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEECC
DTTVRVDSRPVAGDPFAVLAATLAEIAEDEPVACPVPFATGLCGVLGYGLGAWLERLAPA
CCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PADRLALPAMTLGVYDCVAAFDLRARKAWIVSSGRPERDPRRRAARALARAEALERRLAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSLVPDETAAAYEKTGSWRAERPRAAILAAIGKTIDAIEAGELFQANITQRFLADLPPGL
HEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
DDLTLYRRLRRLSPAPFAALVGCGADHRLIGASPERFLRLGAEGRVETRPIKGTRRRDAD
HHHHHHHHHHHCCCCCHHHHHCCCCCCCEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
PARDAAQAAALVASEKDRAENLMIVDLMRNDLGRVCAIGSVRVPRLIALESFASVHHLVS
HHHHHHHHHHHHHCCHHHHCCEEEHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHH
AVEGRLRPGLGAIDLLRACFPGGSVTGAPKIRAMDLITALEPARRGWYCGSVAWIGADGA
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCEEEECCCCC
MDSNIVIRSLTRAGATLIAQAGGAITAPSDPAEEYEESLIKMAPLLSALDGIER
CCCCHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLHIRPIAFADPLTLVPALAKDPVFAFLDSAAADPGAGDEDRGRYSYLCADPWRVITAD
CEEEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEECC
DTTVRVDSRPVAGDPFAVLAATLAEIAEDEPVACPVPFATGLCGVLGYGLGAWLERLAPA
CCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PADRLALPAMTLGVYDCVAAFDLRARKAWIVSSGRPERDPRRRAARALARAEALERRLAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSLVPDETAAAYEKTGSWRAERPRAAILAAIGKTIDAIEAGELFQANITQRFLADLPPGL
HEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
DDLTLYRRLRRLSPAPFAALVGCGADHRLIGASPERFLRLGAEGRVETRPIKGTRRRDAD
HHHHHHHHHHHCCCCCHHHHHCCCCCCCEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
PARDAAQAAALVASEKDRAENLMIVDLMRNDLGRVCAIGSVRVPRLIALESFASVHHLVS
HHHHHHHHHHHHHCCHHHHCCEEEHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHH
AVEGRLRPGLGAIDLLRACFPGGSVTGAPKIRAMDLITALEPARRGWYCGSVAWIGADGA
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCEEEECCCCC
MDSNIVIRSLTRAGATLIAQAGGAITAPSDPAEEYEESLIKMAPLLSALDGIER
CCCCHHHHHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]