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The map label for this gene is lin [H]

Identifier: 83592310

GI number: 83592310

Start: 1159249

End: 1160091

Strand: Direct

Name: lin [H]

Synonym: Rru_A0974

Alternate gene names: 83592310

Gene position: 1159249-1160091 (Clockwise)

Preceding gene: 83592309

Following gene: 83592311

Centisome position: 26.63

GC content: 68.21

Gene sequence:

>843_bases
ATGAACGATCTGATGCGTGACTTGGCGCCGATCTCGGCCAAGGCCTGGGCGGAAATTGAAACGGAAGCGCGCGGGACCCT
GACGGTCACCCTGGCGGCGCGCAAGGTGGTGGACTTCAAGGGACCGCTGGGCTGGGACGCCTCGTCGGTGTCCTTGGGGC
GGACCGAGGCTTTGGCCGAGGAGCCCAAGGCGGCGGGAAGCGCCGCCGTGGTCACGGTGCGCAAGCGCGCCGTTCAGCCG
CTGATCGAGCTCTGCGTGCCTTTCACTTTGAAGCGCGCCGAGTTGGAGGCGATCGCCCGCGGCGCGTCGGATGCCGATCT
TGATCCGGTGATCGAGGCCGCCCGCGCCATCGCCATCGCCGAGGACCGCGCCGTGTTCCACGGCTTCGCCGCCGGCGGCA
TCACCGGCATCGGCGAAGCCTCGGCCGAGCATGCCCTGGATCTGCCCGCCGACCTCGCCGATTTCCCCGGCGTGCTGGTG
CGCGCTCTGGCGGTGCTGCGCGATCGCGGCGTCGATGGCCCTTACGCCCTGGTGCTGGGCCGCACCGTCTATCAGCAGCT
GATGGAAACCACCACGCCGGGCGGCTATCCGGTGCTTCAGCACGTGCGCCGGCTGTTCGAAGGCCCGCTGATCTGGGCCC
CGGGTGTCGATGGCGCGATGCTGATCAGCCAGCGCGGCGGCGATTTCGAACTGACCGTTGGCCGCGATTTCTCGATCGGC
TATCACGATCACGACGCCCAGTCCGTGCATCTTTATCTGCAAGAAAGCATGACCTTCCGCTGCCTTGGCCCCGAAGCCGC
CGTGCCGCTGCGTGGCCTGTCCCAGGCCGCCACCAAGGCATAA

Upstream 100 bases:

>100_bases
ACCCCGGTTGTAAGCCAGTCTGTCCATTTTTTGTGATGTCTGGCGCGGAGATGACCGCCGCCGGACTCCTCCCCCTTATA
ATGATGTGTTCGAGGATTCC

Downstream 100 bases:

>100_bases
GCATCTTCTTGAAAAAAGGTGTTGCCAGGACGGTCGGGACAGCGTAAAACCCCGCCCTCCGCAGCACCCGCGTCCCCATC
GTCTAGCGGTCCAGGACGTC

Product: Linocin_M18 bacteriocin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAEEPKAAGSAAVVTVRKRAVQP
LIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIAEDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLV
RALAVLRDRGVDGPYALVLGRTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIG
YHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA

Sequences:

>Translated_280_residues
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAEEPKAAGSAAVVTVRKRAVQP
LIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIAEDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLV
RALAVLRDRGVDGPYALVLGRTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIG
YHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA
>Mature_280_residues
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAEEPKAAGSAAVVTVRKRAVQP
LIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIAEDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLV
RALAVLRDRGVDGPYALVLGRTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIG
YHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA

Specific function: Bacteriocin that has antimicrobial activity against a wide range of Gram-positive bacteria, including L.monocytogenes, B.cereus and S.aureus. May have a protease activity [H]

COG id: COG1659

COG function: function code S; Uncharacterized protein, linocin/CFP29 homolog

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007544 [H]

Pfam domain/function: PF04454 Linocin_M18 [H]

EC number: NA

Molecular weight: Translated: 29733; Mature: 29733

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAE
CCHHHHHHCCCCHHHHHHECCCCCCEEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHH
EPKAAGSAAVVTVRKRAVQPLIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIA
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLVRALAVLRDRGVDGPYALVLG
HCCHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCEEEEECCCEECC
YHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA
CCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNDLMRDLAPISAKAWAEIETEARGTLTVTLAARKVVDFKGPLGWDASSVSLGRTEALAE
CCHHHHHHCCCCHHHHHHECCCCCCEEEEEEEEHHHHCCCCCCCCCCCCCCCCHHHHHHH
EPKAAGSAAVVTVRKRAVQPLIELCVPFTLKRAELEAIARGASDADLDPVIEAARAIAIA
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EDRAVFHGFAAGGITGIGEASAEHALDLPADLADFPGVLVRALAVLRDRGVDGPYALVLG
HCCHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RTVYQQLMETTTPGGYPVLQHVRRLFEGPLIWAPGVDGAMLISQRGGDFELTVGRDFSIG
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCEEEEECCCEECC
YHDHDAQSVHLYLQESMTFRCLGPEAAVPLRGLSQAATKA
CCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8919789 [H]