Click here to switch to the map view.

The map label for this gene is yefM [H]

Identifier: 83592311

GI number: 83592311

Start: 1160356

End: 1160613

Strand: Direct

Name: yefM [H]

Synonym: Rru_A0975

Alternate gene names: 83592311

Gene position: 1160356-1160613 (Clockwise)

Preceding gene: 83592310

Following gene: 83592314

Centisome position: 26.66

GC content: 63.18

Gene sequence:

>258_bases
ATGCGTGTCGTGACGTTCTCGGAAGCTCGCAACAGCCTCAAGGCCACCCTTGACCGGGTCGTTGAGGATGCGGATTACAC
GGTTATCGCCCGCCGCGATGCGCCCGACGCCGTAGTGATGTCCCTCGACACCTTCAACAGCCTGATGGAAACGGTCCACC
TGCTGCGCTCGCCGGCCAATGCCGCCCATCTGGCCCGCTCCATCGCCCACTATCGCCAGGGCCAAGTCGCGGCGCGCGAT
CTGGTCGATAATGAATAG

Upstream 100 bases:

>100_bases
TGCAAAACCCCCGCCCTCCGTGGCGGGGGTTTTGCGTTGGAGGGCTTGTGACGGCCGGGGGCAGGGGGCAAGTTGTCCTA
TAAACAGGACAGGGGGTGCC

Downstream 100 bases:

>100_bases
GGGGCTTTCCCGCCTCGTGTGGACCGAGGCGGCTTGGGACGTAGGTCGGAGCGCGTTCGGCTACATTAATGCCGTATGTG
TGGGCTCTGCGTGATTCCGA

Product: prevent-host-death protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 85

Protein sequence:

>85_residues
MRVVTFSEARNSLKATLDRVVEDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLRSPANAAHLARSIAHYRQGQVAARD
LVDNE

Sequences:

>Translated_85_residues
MRVVTFSEARNSLKATLDRVVEDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLRSPANAAHLARSIAHYRQGQVAARD
LVDNE
>Mature_85_residues
MRVVTFSEARNSLKATLDRVVEDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLRSPANAAHLARSIAHYRQGQVAARD
LVDNE

Specific function: Part of a toxin-antitoxin (TA) module. Antitoxin that counteracts the effect of the YoeB mRNA interferase. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor [H]

COG id: COG2161

COG function: function code D; Antitoxin of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YefM antitoxin family [H]

Homologues:

Organism=Escherichia coli, GI87082026, Length=83, Percent_Identity=43.3734939759036, Blast_Score=75, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006442 [H]

Pfam domain/function: PF02604 PhdYeFM [H]

EC number: NA

Molecular weight: Translated: 9454; Mature: 9454

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVTFSEARNSLKATLDRVVEDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLRSPAN
CCEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCH
AAHLARSIAHYRQGQVAARDLVDNE
HHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MRVVTFSEARNSLKATLDRVVEDADYTVIARRDAPDAVVMSLDTFNSLMETVHLLRSPAN
CCEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCH
AAHLARSIAHYRQGQVAARDLVDNE
HHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]